Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pavla Nedbalová"'
Autor:
Michalina Kazek, Lenka Chodáková, Katharina Lehr, Lukáš Strych, Pavla Nedbalová, Ellen McMullen, Adam Bajgar, Stanislav Opekar, Petr Šimek, Martin Moos, Tomáš Doležal
Publikováno v:
PLoS Biology, Vol 22, Iss 5, p e3002299 (2024)
Activation of immune cells requires the remodeling of cell metabolism in order to support immune function. We study these metabolic changes through the infection of Drosophila larvae by parasitoid wasp. The parasitoid egg is neutralized by differenti
Externí odkaz:
https://doaj.org/article/6ea8d92953f143c794e2c9f4f1eac24f
Autor:
Gabriela Krejčová, Adéla Danielová, Pavla Nedbalová, Michalina Kazek, Lukáš Strych, Geetanjali Chawla, Jason M Tennessen, Jaroslava Lieskovská, Marek Jindra, Tomáš Doležal, Adam Bajgar
Publikováno v:
eLife, Vol 8 (2019)
Macrophage-mediated phagocytosis and cytokine production represent the front lines of resistance to bacterial invaders. A key feature of this pro-inflammatory response in mammals is the complex remodeling of cellular metabolism towards aerobic glycol
Externí odkaz:
https://doaj.org/article/988c82f9ff7246d7af99d3165741a2d1
Autor:
Pavla Nedbalová, Adam Bajgar, Tomas Dolezal, Julie Kovarova, Gabriela Krejčová, Nick Kamps-Hughes, Helena Zemanova, Lukas Strych
In response to invading pathogens, macrophages metabolically polarize toward Hif1α-induced aerobic glycolysis, requiring increased supply of nutrients. Here, we show that in order to obtain sufficient resources, Drosophila macrophages release the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad533f3b1d2424bb0765d6c8231b9c18
https://doi.org/10.1101/2020.09.24.311670
https://doi.org/10.1101/2020.09.24.311670
Autor:
Jason M. Tennessen, Geetanjali Chawla, Michalina Kazek, Marek Jindra, Adéla Danielová, Adam Bajgar, Pavla Nedbalová, Gabriela Krejčová, Lukas Strych, Jaroslava Lieskovská, Tomáš Doležal
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Macrophage-mediated phagocytosis and cytokine production represent the front lines of resistance to bacterial invaders. A key feature of this pro-inflammatory response in mammals is the complex remodeling of cellular metabolism towards aerobic glycol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a80c02c52568a6bb93ad637f7f93d9
https://doi.org/10.7554/elife.50414
https://doi.org/10.7554/elife.50414
Autor:
Jason M. Tennessen, Pavla Nedbalová, Tomáš Doležal, Lukas Strych, Geetanjali Chawla, Gabriela Krejčová, Jaroslava Lieskovská, Michalina Kazek, Adam Bajgar, Marek Jindra, Adéla Danielová
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d3583b1ac2995c50bf9d1f3cea5dd1c
https://doi.org/10.7554/elife.50414.021
https://doi.org/10.7554/elife.50414.021
Autor:
Markéta Kovářová, Adéla Jačková, Petra Sváčková, Jan Kopecký, Denisa Sváčková, Julie Fáberová, Zuzana Kumžáková, Marie Horká, Pavla Nedbalová, Veronika Caisova, Jan Ženka, Eva Waldmannová, Nikol Vácová
Publikováno v:
International Immunopharmacology. 39:295-306
The idea of using killed microorganisms or their parts for a stimulation of immunity in the cancer immunotherapy is very old, but the question of interactions and binding of these preparations to tumor cells has not been addressed so far. The attachm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0510b5eba4c94f4f69be648f7fc0d98
https://doi.org/10.1016/j.intimp.2016.08.004
https://doi.org/10.1016/j.intimp.2016.08.004
Publikováno v:
Insect biochemistry and molecular biology. 109
Mounting an immune response is an energy-consuming process. Activating immune functions requires the synthesis of many new molecules and the undertaking of numerous cellular tasks and it must happen rapidly. Therefore, immune cells undergo a metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471ca4d4b0f758c209bf97ec4bb46766
https://pubmed.ncbi.nlm.nih.gov/30959109
https://pubmed.ncbi.nlm.nih.gov/30959109
Effective cancer immunotherapy based on combination of TLR agonists with stimulation of phagocytosis
Autor:
Lucie Paďouková, Veronika Caisova, Ondřej Uher, Jindřich Chmelař, Jan Kopecký, Karolina Kvardova, Kamila Masakova, Pavla Nedbalová, Ivana Jochmanova, Gabriela Krejčová, Jan Ženka
Publikováno v:
International immunopharmacology. 59
Immunotherapy emerges as a fundamental approach in cancer treatment. Up to date, the efficacy of numerous different immunotherapies has been evaluated. The use of microorganisms or their parts for immune cell activation, referred to as Pathogen-Assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca7c6cb1c87aeb87d9b539b28474f0e
https://pubmed.ncbi.nlm.nih.gov/29635103
https://pubmed.ncbi.nlm.nih.gov/29635103