Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Pavla Kadlecová"'
Autor:
Bernhard Husch, Guenter Stix, Pavla Kadlecová, Guenther Krumpl, Juri Hodisch, Hans Domanovits, Michaela Trebs, Martin Unger, Michael Wolzt
Publikováno v:
Circulation Journal. 84:33-42
BACKGROUND We investigated for the first time the suitability of landiolol, an ultra-short-acting β1-specific β-blocker, for the treatment of atrial fibrillation/atrial flutter (AF/AFL) in Caucasian patients.Methods and Results:The 20 study patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9519cce4244c3bbb0647fec50a34fe82
https://doi.org/10.1253/circj.cj-19-0661
https://doi.org/10.1253/circj.cj-19-0661
Publikováno v:
Clinical pharmacology in drug developmentReferences. 11(3)
We investigated the hemodynamic effects of 2 short-acting β1 -blockers, landiolol and esmolol, in the continuous presence of dobutamine in a prospective, single-center, randomized, crossover study in 16 healthy White volunteers. Dobutamine was infus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc00d7f73c4e1ae34970624a28c6a2b8
https://pubmed.ncbi.nlm.nih.gov/34655181
https://pubmed.ncbi.nlm.nih.gov/34655181
Publikováno v:
Cureus
Background and objective This study involved an investigation into the pharmacokinetic and pharmacodynamic behavior of esmolol in the presence of dobutamine in healthy subjects of European ancestry. Methods We conducted a single-center, prospective r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674029650d38bccf197ffb86c0a8de72
https://pubmed.ncbi.nlm.nih.gov/33500851
https://pubmed.ncbi.nlm.nih.gov/33500851
Publikováno v:
BMC Pharmacology & Toxicology
Background To study the pharmacokinetic and -dynamic behavior of landiolol in the presence of dobutamine in healthy subjects of European ancestry. Methods We conducted a single-center, prospective randomized study in 16 healthy subjects each receivin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd156473d0736cb1dee792f93abf9b0
https://doi.org/10.1186/s40360-020-00462-x
https://doi.org/10.1186/s40360-020-00462-x
Autor:
Mervyn Singer, Michael Zörer, Fabio Guarracino, Michael Joannidis, Pavel Dostál, Gianni Biancofiore, Francesca Pratesi, Sebastian Rehberg, Kurt Krejcy, Peter Radermacher, Pavla Kadlecová, Barbara Grohmann-Izay, G. Krumpl, Christian Siebers, Gottfried Heinz, Andrea Morelli, Vladimir Cerny, Olivier Bouvet, Martin Unger, Helmut Trimmel, Massimo Girardis, Christoph Klade
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-8 (2018)
Trials
Trials
Background In patients with septic shock, the presence of an elevated heart rate (HR) after fluid resuscitation marks a subgroup of patients with a particularly poor prognosis. Several studies have shown that HR control in this population is safe and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a0e36f7a8d1c52e45d570d3f6733e3
http://link.springer.com/article/10.1186/s13063-018-3024-6
http://link.springer.com/article/10.1186/s13063-018-3024-6
Autor:
Juri Hodisch, Gabriele Maurer, Michaela Trebs, G. Krumpl, Bernhard Husch, Ivan Ulč, Pavla Kadlecová
Publikováno v:
Journal of Cardiovascular Pharmacology. 70:42-51
Pharmacokinetics, pharmacodynamics, safety, and tolerability of long-term administration of landiolol, a fast-acting cardioselective β-blocker, were investigated for the first time in white subjects in a prospective clinical trial. Blood concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af430641af9c46140a7b36994a224d66
https://doi.org/10.1097/fjc.0000000000000495
https://doi.org/10.1097/fjc.0000000000000495
Autor:
Jiri Vanicek, Pavla Kadlecová, Robert Mikulik, Petra Cimflova, Petr Vanek, Bijoy K Menon, Ondrej Volny
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 26:19-24
Objectives CT angiography (CTA) is recommended as a standard of stroke imaging. We investigated accuracy and precision of standard or single-phase CTA as compared with novel technique or multiphase CTA in clot detection in the middle cerebral artery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0091edccdedbb6b1dea872e657f3c5
https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.08.023
https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.08.023
Publikováno v:
Clinical Drug Investigation
Background and Objective Once-daily oral fingolimod is approved in the EU as escalation treatment for adult patients with highly active relapsing multiple sclerosis (MS). The efficacy and safety profiles of fingolimod have been well established in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24a2e9e669a2ee162acbe0785fcdd3f
https://doi.org/10.1007/s40261-016-0471-2
https://doi.org/10.1007/s40261-016-0471-2
Publikováno v:
European Journal of Pharmaceutical Sciences. 92:64-73
Background To date, no data have been reported on the pharmacokinetic and pharmacodynamic properties of landiolol, a fast-acting cardioselective β1-adrenergic antagonist, in non-Asian subjects. The aim of this study was to compare two landiolol form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966e36a8a31807ace698249cb348cef1
https://doi.org/10.1016/j.ejps.2016.06.022
https://doi.org/10.1016/j.ejps.2016.06.022
Autor:
Robert D. Brown, Robert Mikulik, Ondrej Volny, Josef Bednarik, Pavla Kadlecová, Viktor Weiss, Tomas Bryndziar, Petra Sedova, Miroslav Zvolsky
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 24:2032-2038
Background Stroke is a common cause of mortality and morbidity in Eastern Europe. However, detailed epidemiological data are not available. The National Registry of Hospitalized Patients (NRHOSP) is a nationwide registry of prospectively collected da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9663644c2aece036e246eb56aa9bc778
https://doi.org/10.1016/j.jstrokecerebrovasdis.2015.04.019
https://doi.org/10.1016/j.jstrokecerebrovasdis.2015.04.019