Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Pavla Jirsová"'
Publikováno v:
Acta Universitatis Carolinae Geographica, Vol 43, Iss 1, Pp 53-62 (2021)
During the last more than twenty years, various types of forest disturbance (i.e. insect outbreak, clearcutting) occurred in the central part of the Šumava Mountains. The bark beetle (Ips typographus [L.]) outbreak in this region resulted in regiona
Externí odkaz:
https://doaj.org/article/dbfc034e7b434f30aa3d93526cc8a5b5
Autor:
Jitka Zluvova, Eva Bártová, Michal Kozubek, Pavla Jirsová, Irena Koutná, Hana Gajová, Renata Taslerová, Stanislav Kozubek
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 129:89-99
Chromosomal aberrations and the nuclear topography of retinoblastoma tumour cells as well as lymphocytes of patients suffering from the familiar or sporadic form of retinoblastoma were studied. Fluorescence in situ hybridisation (FISH) on fresh, para
Autor:
Eva Bártová, Hana Gajová, Stanislav Kozubek, Michal Kozubek, Pavla Jirsová, Emilie Lukášová, Magdalena Skalníková, Michael Hausmann, Irena Koutná, Alena Gaňová
Publikováno v:
Journal of Structural Biology. 139:76-89
The nuclear arrangement of the ABL, c-MYC, and RB1 genes was quantitatively investigated in human undifferentiated HL-60 cells and in a terminally differentiated population of human granulocytes. The ABL gene was expressed in both cell types, the c-M
Autor:
Pavla Jirsová, Eva Bártová, Emilie Lukášová, Michal Kozubek, Magdalena Skalníková, Irena Koutná, Stanislav Kozubek, Alena Cafourková
Publikováno v:
Scopus-Elsevier
Fluorescence in situ hybridization (FISH) combined with high-resolution cytometry was used to determine the topographic characteristics of the centromeric heterochromatin (of the chromosomes 6, 8, 9, 17) and the tumor suppressor gene TP53 (which is l
Publikováno v:
Cellular and molecular life sciences : CMLS. 60(5)
The nuclear architecture of selected chromosomes in apoptotic nuclei of human leukemic cells K-562 and HL-60 was investigated. Etoposide and prolonged confluence were used for the induction of apoptosis. DAPI as well as TUNEL labeling of apoptotic nu
Autor:
Michal Kozubek, Stanislav Kozubek, Eva Bártová, Renata Taslerová, Emilie Lukášová, Pavla Jirsová
Publikováno v:
Human genetics. 112(2)
Standard and repeated fluorescence in situ hybridization and high-resolution cytometry were used to study topographical parameters of chromosome 11 and 22 territories, EWSR1 and FLI1 genes, and other genetic elements of these chromosomes in human lym
Autor:
Eva Bártová, Alena Ganová, Martin Falk, Pavla Jirsová, Emilie Lukášová, Stanislav Kozubek, Irena Koutná, Renata Paseková, Michal Kozubek
Publikováno v:
Chromosoma. 111(5)
A complex study of the spatial arrangement of different genetic elements (genes, centromeres and chromosomal domains) in the cell nucleus is presented and the principles of this arrangement are discussed. We show that the radial location of genetic e
Autor:
Magdalena Skalníková, R. D. Govorun, Alena Cafourková, Pavla Jirsová, Emilie Lukášová, Eva Bártová, Irena Koutná, R. Paseková, Stanislav Kozubek, Michal Kozubek, Evgeny Krasavin
Publikováno v:
International journal of radiation biology. 77(4)
To detect the frequencies of interchanges among 11 chromosomes in lymphocytes irradiated with gamma-rays and to find out whether these frequencies reflect the proximity of some of these chromosomes within the interphase nucleus.Exchange aberrations w
Autor:
Emilie Lukášová, Pavla Jirsová, Magdalena Skalníková, Stanislav Kozubek, Eva Bártová, Alena Cafourková, Renata Paseková, Michal Kozubek, Irena Koutná
Publikováno v:
Scopus-Elsevier
The structural organisation of chromatin in eukaryotes plays an important role in a number of biological processes. Our results provide a comprehensive insight into the nuclear topography of human peripheral blood granulocytes, mainly neutrophils. Th
Autor:
Kateřina Buchnı́čková, Eva Bártová, Michal Kozubek, Magdalena Skalníková, Stanislav Kozubek, Pavla Jirsová, Emilie Lukášová
Publikováno v:
Leukemia research. 24(3)
abl and bcr genes play an important role in the diagnostics of chronic myelogenous leukemia (CML). The translocation of these genes results in an abnormal chromosome 22 called the Philadelphia chromosome (Ph). The chimeric bcr-abl gene is a fundament