Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pavla Bouchalova"'
Autor:
Petr Lapcik, Klara Synkova, Lucia Janacova, Pavla Bouchalova, David Potesil, Rudolf Nenutil, Pavel Bouchal
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-7 (2024)
Abstract Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, and deeper proteome coverage is needed for its molecular characterization. We present comprehensive library of targeted mass spectrometry assays specific f
Externí odkaz:
https://doaj.org/article/2d12a41b2f2b49e78e7f63f0d2362dd3
Autor:
Petr Lapcik, Petr Sulc, Lucia Janacova, Katerina Jilkova, David Potesil, Pavla Bouchalova, Petr Müller, Pavel Bouchal
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-25 (2023)
Abstract Background Desmocollin-1 (DSC1) is a desmosomal transmembrane glycoprotein that maintains cell-to-cell adhesion. DSC1 was previously associated with lymph node metastasis of luminal A breast tumors and was found to increase migration and inv
Externí odkaz:
https://doaj.org/article/fbfd7723f58e4e80a6b4c70304ccc736
Autor:
Lucia Janacova, Michaela Stenckova, Petr Lapcik, Sarka Hrachovinova, Pavla Bouchalova, David Potesil, Roman Hrstka, Petr Müller, Pavel Bouchal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Catechol-O-methyl transferase (COMT) is involved in detoxification of catechol estrogens, playing cancer-protective role in cells producing or utilizing estrogen. Moreover, COMT suppressed migration potential of breast cancer (BC) cells. To
Externí odkaz:
https://doaj.org/article/b1c0c33a529140bdaa207c91df10f273
Autor:
Pavla Bouchalova, Pavel Bouchal
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-22 (2022)
Abstract Cell migration and invasiveness significantly contribute to desirable physiological processes, such as wound healing or embryogenesis, as well as to serious pathological processes such as the spread of cancer cells to form tumor metastasis.
Externí odkaz:
https://doaj.org/article/b33e83fc96d3482ba356bdc0c48d8630
Autor:
Pavla Bouchalova, Jindrich Beranek, Petr Lapcik, David Potesil, Jan Podhorec, Alexandr Poprach, Pavel Bouchal
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1145 (2021)
Renal cell carcinoma (RCC) represents about 2–3% of all cancers with over 400,000 new cases per year. Sunitinib, a vascular endothelial growth factor tyrosine kinase receptor inhibitor, has been used mainly for first-line treatment of metastatic cl
Externí odkaz:
https://doaj.org/article/5f4a174c514e4526ab6fe5e567ad82ae
Autor:
Pavla Bouchalova, Lucia Sommerova, David Potesil, Andrea Martisova, Petr Lapcik, Veronika Koci, Alex Scherl, Petr Vonka, Joan Planas-Iglesias, Eric Chevet, Pavel Bouchal, Roman Hrstka
Publikováno v:
Molecular and Cellular Proteomics
Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2022, pp.100188. ⟨10.1016/j.mcpro.2021.100188⟩
Molecular and Cellular Proteomics, 2022, 21 (2), pp.100188. ⟨10.1016/j.mcpro.2021.100188⟩
Molecular and Cellular Proteomics, American Society for Biochemistry and Molecular Biology, 2022, pp.100188. ⟨10.1016/j.mcpro.2021.100188⟩
Molecular and Cellular Proteomics, 2022, 21 (2), pp.100188. ⟨10.1016/j.mcpro.2021.100188⟩
International audience; Anterior gradient 2 (AGR2) is an endoplasmic reticulum (ER)-resident protein disulfide isomerase (PDI) known to be overexpressed in many human epithelial cancers and is involved in cell migration, cellular transformation, angi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8dbf616412ec0a44b1289051ae2773
https://hal.archives-ouvertes.fr/hal-03514541
https://hal.archives-ouvertes.fr/hal-03514541
Autor:
Pavla, Bouchalova, Rudolf, Nenutil, Petr, Muller, Roman, Hrstka, M Virginia, Appleyard, Karen, Murray, Lee B, Jordan, Colin A, Purdie, Philip, Quinlan, Alastair M, Thompson, Borivoj, Vojtesek, Philip J, Coates
Publikováno v:
The Journal of pathology. 233(3)
Many human cancers contain missense TP53 mutations that result in p53 protein accumulation. Although generally considered as a single class of mutations that abrogate wild-type function, individual TP53 mutations may have specific properties and prog