Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pavlína Kellerová"'
Autor:
Diana Dimunová, Martina Navrátilová, Pavlína Kellerová, Martin Ambrož, Lenka Skálová, Petra Matoušková
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 19, Iss , Pp 56-64 (2022)
Albendazole (ABZ) is an anthelmintic frequently used to treat haemonchosis, a common parasitosis of ruminants caused by the gastrointestinal nematode Haemonchus contortus. This parasite is able to protect itself against ABZ via the formation of inact
Externí odkaz:
https://doaj.org/article/c645fcaf340349f6b61b66e8c3e43697
Autor:
Pavlína Kellerová, Lucie Raisová Stuchlíková, Petra Matoušková, Karolína Štěrbová, Jiří Lamka, Martina Navrátilová, Ivan Vokřál, Barbora Szotáková, Lenka Skálová
Publikováno v:
Veterinary Research, Vol 51, Iss 1, Pp 1-17 (2020)
Abstract The efficacy of anthelmintic therapy of farm animals rapidly decreases due to drug resistance development in helminths. In resistant isolates, the increased expression and activity of drug-metabolizing enzymes (DMEs), e.g. cytochromes P450 (
Externí odkaz:
https://doaj.org/article/fcef1c6e6dee49ce88c29696feba82c4
Autor:
Petra Matoušková, Lenka Lecová, Roz Laing, Diana Dimunová, Heiko Vogel, Lucie Raisová Stuchlíková, Linh Thuy Nguyen, Pavlína Kellerová, Ivan Vokřál, Jiří Lamka, Barbora Szotáková, Marián Várady, Lenka Skálová
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 3, Pp 420-429 (2018)
UDP-glycosyltransferases (UGT), catalysing conjugation of UDP-activated sugar donors to small lipophilic chemicals, are widespread in living organisms from bacteria to fungi, plant, or animals. The progress of genome sequencing has enabled an assessm
Externí odkaz:
https://doaj.org/article/91d5de2796d44a0da5a5dadbc53bc0ed
Autor:
Pavlína Kellerová, Martina Navrátilová, Linh Thuy Nguyen, Diana Dimunová, Lucie Raisová Stuchlíková, Karolína Štěrbová, Lenka Skálová, Petra Matoušková
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The nematode Haemonchus contortus, a gastrointestinal parasite of ruminants, can severely burden livestock production. Although anthelmintics are the mainstay in the treatment of haemonchosis, their efficacy diminishes due to drug-resistance developm
Externí odkaz:
https://doaj.org/article/d09461ddfdaa48478f87939a33797250
Publikováno v:
Journal of Eukaryotic Microbiology. 66:899-910
The enzymes pyruvate ferredoxin oxidoreductase (PFO), malic enzyme (ME), and the α- and β-subunits of succinyl-CoA synthetase (SCS) catalyze key steps of energy metabolism in Trichomonas vaginalis hydrogenosomes. These proteins have also been chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6be3815294d400aa8bfa2d813fc105
https://doi.org/10.1111/jeu.12741
https://doi.org/10.1111/jeu.12741
Autor:
Petra Matoušková, Pavlína Kellerová, Jiří Lamka, Ivan Vokřál, Michael Pasák, Barbora Szotáková, Lenka Skálová, Markéta Zajíčková
Publikováno v:
Veterinary parasitology. 273
Haemonchus contortus, one of the most pathogenic of all small ruminant parasites, have developed resistance to all used anthelmintics. Detoxification enzymes, e.g. cytochromes P450 (CYPs) and efflux transporters P-glycoproteins (P-gps), which represe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e23fd50dafc283129b9a21a5cf45bf
https://pubmed.ncbi.nlm.nih.gov/31442889
https://pubmed.ncbi.nlm.nih.gov/31442889
Autor:
Pavlína Kellerová, Jan Tachezy
Publikováno v:
International journal for parasitology. 47(5)
Trichomonads are known to inhabit the oral cavities of various mammals, including dogs, cats and horses. However, little attention has been paid to species identification, prevalence and zoonotic potential of these parasites, although their hosts liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314ae66c7723533ef51728b71905c1ba
https://pubmed.ncbi.nlm.nih.gov/28238869
https://pubmed.ncbi.nlm.nih.gov/28238869