Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Pavia-Jimenez A"'
Autor:
Elias, Roy, Tcheuyap, Vanina T., Kaushik, Akash K., Singla, Nirmish, Gao, Ming, Reig Torras, Oscar, Christie, Alana, Mulgaonkar, Aditi, Woolford, Layton, Stevens, Christina, Kettimuthu, Kavitha Priya, Pavia-Jimenez, Andrea, Boroughs, Lindsey K., Joyce, Allison, Dakanali, Marianna, Notgrass, Hollis, Margulis, Vitaly, Cadeddu, Jeffrey A., Pedrosa, Ivan, Williams, Noelle S., Sun, Xiankai, DeBerardinis, Ralph J., Öz, Orhan K., Zhong, Hua, Seshagiri, Somasekar, Modrusan, Zora, Cantarel, Brandi L., Kapur, Payal, Brugarolas, James
Publikováno v:
In Cell Reports 23 November 2021 37(8)
Autor:
James Brugarolas, W. Marston Linehan, Charis Eng, Patricia L.M. Dahia, Xian-Jin Xie, Chao Xing, Adam R. Metwalli, Maria J. Merino, Nick Grishin, Lisa Kinch, Lindsay Middelton, James Peterson, Christopher J. Ricketts, Cathy D. Vocke, Alana Christie, Andrea Pavia-Jimenez, Samuel Peña-Llopis, Jessica L. Mester, Laura S. Schmidt, Megan N. Farley
PDF file - 233K, VHL mutation status in some but not all tumors from Family NCI-1326.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1a107592d76de15555689e3e2f1575
https://doi.org/10.1158/1541-7786.22509765
https://doi.org/10.1158/1541-7786.22509765
Autor:
James Brugarolas, W. Marston Linehan, Charis Eng, Patricia L.M. Dahia, Xian-Jin Xie, Chao Xing, Adam R. Metwalli, Maria J. Merino, Nick Grishin, Lisa Kinch, Lindsay Middelton, James Peterson, Christopher J. Ricketts, Cathy D. Vocke, Alana Christie, Andrea Pavia-Jimenez, Samuel Peña-Llopis, Jessica L. Mester, Laura S. Schmidt, Megan N. Farley
PDF file - 104K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813587ebb55f45d8b3e66d7e687a35f3
https://doi.org/10.1158/1541-7786.22509762
https://doi.org/10.1158/1541-7786.22509762
Autor:
Kapur, Payal, Peña-Llopis, Samuel, Christie, Alana, Zhrebker, Leah, Pavía-Jiménez, Andrea, Rathmell, W Kimryn, Xie, Xian-Jin, Brugarolas, James
Publikováno v:
In Lancet Oncology February 2013 14(2):159-167
Autor:
Bray Denard, Andrea Pavia-Jimenez, Weina Chen, Noelle S Williams, Harris Naina, Robert Collins, James Brugarolas, Jin Ye
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129233 (2015)
Doxorubicin has been shown to inhibit proliferation of cancer cells through proteolytic activation of CREB3L1 (cAMP response element binding protein 3-like 1), a transcription factor synthesized as a membrane-bound precursor. Upon doxorubicin treatme
Externí odkaz:
https://doaj.org/article/13d1229d141540a5b643ffc9d0a2992d
Autor:
Hollis Notgrass, Hua Zhong, Andrea Pavia-Jimenez, Vanina Tcheuyap, Ming Gao, Vitaly Margulis, Roy Elias, Ivan Pedrosa, Aditi Mulgaonkar, Oscar Reig Torras, Nirmish Singla, Christina Stevens, Zora Modrusan, Layton Woolford, Brandi L. Cantarel, Xiankai Sun, Marianna Dakanali, Ralph J. DeBerardinis, Somasekar Seshagiri, Kavitha Priya Kettimuthu, Allison Joyce, Jeffrey A. Cadeddu, Noelle S. Williams, Akash K. Kaushik, Orhan K. Öz, Payal Kapur, Alana Christie, Lindsey K. Boroughs, James Brugarolas
Publikováno v:
Cell reports
SUMMARY Renal cell carcinoma (RCC) encompasses a heterogenous group of tumors, but representative preclinical models are lacking. We previously showed that patient-derived tumorgraft (TG) models recapitulate the biology and treatment responsiveness.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0aed6967cf60b9ef3fc21badc5d602
https://doi.org/10.1016/j.celrep.2021.110055
https://doi.org/10.1016/j.celrep.2021.110055
Autor:
Paul Yell, Farrah Homayoun, Xiankai Sun, Ivan Pedrosa, Naseem J. Zojwalla, Tae Hyun Hwang, Andrea Pavia-Jimenez, Wallace Eli M, Tai Wong, Wenfang Chen, Allison Joyce, Nirav V. Patel, Renée M. McKay, Xian Jin Xie, James Brugarolas, Kevin D. Courtney, James P. Rizzi, Payal Kapur, Kevin H. Gardner, Eboni Holloman, Haley Hill, Min Kim, Richard K. Bruick, John A. Josey, Alana Christie, Jenny Chang, He Zhang, Eugene P. Frenkel, Yuanqing Ma, Heather Geiger, Guiyang Hao, Yang Xie, Qurratulain Yousuf, Catherine Reeves
Publikováno v:
Nature. 539:112-117
Clear cell renal cell carcinoma (ccRCC) is characterized by inactivation of the von Hippel-Lindau tumour suppressor gene (VHL). Because no other gene is mutated as frequently in ccRCC and VHL mutations are truncal, VHL inactivation is regarded as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323b60296507f0be5c9fc30b0ac74a79
https://doi.org/10.1038/nature19796
https://doi.org/10.1038/nature19796
Autor:
Andrea Pavia-Jimenez, Payal Kapur, Nicholas C. Wolff, James Brugarolas, Mridula Vishwanath, Bruce A. Posner, Xian Jin Xie, Alana Christie, Renée M. McKay, Shane Alexander, Vanina Tcheuyap, Noelle S. Williams
Publikováno v:
Oncotarget
Renal cell carcinoma (RCC) accounts for 85% of primary renal neoplasms, and is rarely curable when metastatic. Approximately 70% of RCCs are clear-cell type (ccRCC), and in >80% the von Hippel-Lindau (VHL) gene is mutated or silenced. We developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af5f9dfda7ca91187ee57cdba93aa44
https://doi.org/10.18632/oncotarget.4773
https://doi.org/10.18632/oncotarget.4773
Autor:
Durga Udayakumar, Alberto Diaz de Leon, Ananth J. Madhuranthakam, Yin Xi, DK Dwivedi, James Brugarolas, Payal Kapur, Ling Cai, Yue Zhang, Ralph J. DeBerardinis, Jeffrey G. McDonald, Zeping Hu, Hyeonwoo Kim, Michael Fulkerson, Jin Ye, Ivan Pedrosa, Takeshi Yokoo, Andrea Pavia-Jimenez, Eun Young Kho, Jeffrey A. Cadeddu, Matthew A. Mitsche, Qing Yuan, Ivan E. Dimitrov, Vitaly Margulis, Robert E. Lenkinski
Publikováno v:
JCI Insight. 2
BACKGROUND Dysregulated lipid and glucose metabolism in clear cell renal cell carcinoma (ccRCC) has been implicated in disease progression, and whole tumor tissue-based assessment of these changes is challenged by the tumor heterogeneity. We studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed07090ae7b98621bde0a55b70cd6225
https://doi.org/10.1172/jci.insight.94278
https://doi.org/10.1172/jci.insight.94278
Publikováno v:
Nature Protocols. 9:1848-1859
Traditionally, xenograft models have been used to study tumors in vivo. However, their utility is reduced by the use of tumor cell lines for implantation. Tumorgrafts (TGs; also known as patient-derived xenografts (PDXs)), which involve patient-deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc05dae4d05eb4ffb85087907290f96a
https://doi.org/10.1038/nprot.2014.108
https://doi.org/10.1038/nprot.2014.108