Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pavel Zrazhevskiy"'
Autor:
Peter T. Nelson, Xiaohu Gao, David Wu, Jonathan R. Fromm, Konstantin Queitsch, Shreeram Akilesh, Lawrence D. True, Wanyi Tai, Pavel Zrazhevskiy, John A. Stamatoyannopoulos
Publikováno v:
Angewandte Chemie. 128:9121-9124
Integration of imaging data across different molecular target types can provide in-depth insight into cell physiology and pathology, but remains challenging owing to poor compatibility between target-type-specific labeling methods. We show that cross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b349358fd7c2c2ba5d948a62dfb6f71
https://doi.org/10.1002/ange.201603945
https://doi.org/10.1002/ange.201603945
Publikováno v:
Small. 12:1035-1043
Nanoparticle probes enable implementation of advanced on-surface assay formats, but impose often underappreciated size-associated constraints, in particular on assay kinetics and sensitivity. The present study highlights substantially slower diffusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06177ec8fa4eba739feae9e1ca008be6
https://doi.org/10.1002/smll.201503101
https://doi.org/10.1002/smll.201503101
Publikováno v:
Particle & Particle Systems Characterization. 31:1291-1299
Fluorescent semiconductor nanoparticles, or quantum dots, have become a promising platform for the engineering of biofunctional probes for a variety of biomedical applications, ranging from multicolor imaging to single-molecule tracking to traceable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae378be2444deb66f8b826608e587b2
https://doi.org/10.1002/ppsc.201400184
https://doi.org/10.1002/ppsc.201400184
Publikováno v:
Bioconjugate Chemistry
High-throughput generation of bispecific molecules promises to expedite the discovery of new molecular therapeutics and guide engineering of novel multifunctional constructs. However, high synthesis complexity and cost have hampered the discovery of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c508a9c76aa6ef0bfa26ce834fcaab
https://doi.org/10.1021/bc5002455
https://doi.org/10.1021/bc5002455
Publikováno v:
Nature Protocols. 8:1852-1869
Here we present a detailed protocol for molecular profiling of individual cultured mammalian cells using multicolor multicycle immunofluorescence with quantum dot probes. It includes instructions for cell culture growth and processing (2 h + 48-72 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70947b75b7a4dbb8593b462132bc7c96
https://doi.org/10.1038/nprot.2013.112
https://doi.org/10.1038/nprot.2013.112
Publikováno v:
Advanced Drug Delivery Reviews. 65:703-718
Nanoparticle-based drug delivery (NDD) has emerged as a promising approach to improving upon the efficacy of existing drugs and enabling the development of new therapies. Proof-of-concept studies have demonstrated the potential for NDD systems to sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df64dea9f2a3b52dcaca967aadf26ea6
https://doi.org/10.1016/j.addr.2012.09.036
https://doi.org/10.1016/j.addr.2012.09.036
Autor:
Xiaohu Gao, Pavel Zrazhevskiy
Publikováno v:
Nano Today. 4:414-428
Successes in biomedical research and state-of-the-art medicine have undoubtedly improved the quality of life. However, a number of diseases, such as cancer, immunodeficiencies, and neurological disorders, still evade conventional diagnostic and thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37de0c9ed558368e4c09e410a1105355
https://doi.org/10.1016/j.nantod.2009.07.004
https://doi.org/10.1016/j.nantod.2009.07.004
Publikováno v:
Scientific Reports
In-cell immunoassays have become a valuable tool for protein expression analysis complementary to established assay formats. However, comprehensive molecular characterization of individual specimens has proven challenging and impractical due to, in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1cab280a04889c93bb372155ac8cff
http://europepmc.org/articles/PMC4556981
http://europepmc.org/articles/PMC4556981
Autor:
Ben Zhong Tang, Pavel Zrazhevskiy, Yuan Li, Anjun Qin, Junwei Li, Carrie Yin Kwan Chan, Ryan T. K. Kwok, Hongkun Li, Xiaohu Gao, Jing Zhi Sun
Publikováno v:
Angewandte Chemie (International ed. in English). 53(49)
An in-depth understanding of dynamic interfacial self-assembly processes is essential for a wide range of topics in theoretical physics, materials design, and biomedical research. However, direct monitoring of such processes is hampered by the poor i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7e89b036be15ab69f479b376f0d649
https://pubmed.ncbi.nlm.nih.gov/25363745
https://pubmed.ncbi.nlm.nih.gov/25363745
Publikováno v:
Small. 12:1034-1034
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06723f8b9666b2526f21aac26c5ce6d8
https://doi.org/10.1002/smll.201670038
https://doi.org/10.1002/smll.201670038