Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pavel V. Khodakovskiy"'
Autor:
Pavel K. Mykhailiuk, Andrey A. Tolmachev, Pavel V. Khodakovskiy, Oleksandr V. Geraschenko, Oleg V. Shishkin
Publikováno v:
Synthesis. 46:1487-1492
Ethyl 2-azolylglyoxylates react smoothly with o-phenylenediamines and 1,2-diaminocyclohexane in acetonitrile at room temperature to give the corresponding 3-azolylquinoxalin-2(1H)-ones and their saturated analogues in good to excellent yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e1576276ceb62a5ece4265561f6ff97
https://doi.org/10.1055/s-0033-1340983
https://doi.org/10.1055/s-0033-1340983
Autor:
Pavel K. Mykhailiuk, Oleksandr N. Shivanyuk, Pavel V. Khodakovskiy, Oleg V. Shishkin, Andrey A. Tolmachev, Oleksandr V. Geraschenko
Publikováno v:
Synthesis. 44:1263-1267
4-Azolylpyridazin-3-ones Ol ksandr V. Geraschenko,*a,b Pavel V. Khodakovskiy,a Oleksandr N. Shivanyuk,b Oleg V. Shishkin,c Pavel K. Mykhailiuk,*a,b Andrey A. Tolmacheva,b a Enamine Ltd., Aleksandra Matrosova Street 23, Kyiv 01103, Ukraine b Departmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80c9b2ab0dfb78d9a29689447210cd8c
https://doi.org/10.1055/s-0031-1290808
https://doi.org/10.1055/s-0031-1290808
Autor:
Olga A. Zaporozhets, Andrey A. Tolmachev, Oleksandr V. Geraschenko, Pavel K. Mykhailiuk, Pavel V. Khodakovskiy, Oleg V. Shishkin
Publikováno v:
Synthesis. 2011:1633-1637
C-Acylation of N-substituted imidazoles with ethyl oxalyl chloride in the presence of N,N-diisopropylethylamine as a base afforded 2-(2-ethoxy-1,2-dioxoethyl)imidazoles in 83―95% yield. Application of this synthetic protocol to thiazoles and triazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b71925453329ef22f6173cceb717f73
https://doi.org/10.1055/s-0030-1260003
https://doi.org/10.1055/s-0030-1260003
Publikováno v:
Synthesis. 2010:1633-1638
Trifluoroacetyl-1,3-benzothiazole reacts with anilines to form the corresponding trifluoromethyl-substituted alcohols. The reaction regioselectivity (ortho/para) was shown to depend strong- ly on the structure of the aniline. meta-Substituted aniline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae713e481da6f445d18b43c40977559e
https://doi.org/10.1055/s-0029-1218712
https://doi.org/10.1055/s-0029-1218712
Publikováno v:
Synthesis. 2010:1195-1199
2-(Trifluoroacetyl)-1,3-azoles reacted with 3-aminopyrazoles to give the corresponding trifluoromethyl-substituted alcohols. The conditions required for the reaction and the yields of the products were highly dependent on the electronic nature of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0b1fdef0a7a660b647ae98325b3723
https://doi.org/10.1055/s-0029-1218657
https://doi.org/10.1055/s-0029-1218657
Publikováno v:
Synthesis. 2010:967-970
A set of highly electrophilic 2-trifluoroacetyl-1,3-heterazoles demonstrated excellent activity in the C-hydroxyalkylation of 1H-indole. The reaction conditions and yields of the corresponding trifluoromethyl-substituted alcohols depend strongly on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c58662362b0137b240a1c997fb5fce7
https://doi.org/10.1055/s-0029-1219219
https://doi.org/10.1055/s-0029-1219219
Publikováno v:
Synthesis. 2010:979-984
A set of electrophilic 2-(trifluoroacetyl)-1,3-azoles demonstrated excellent activity in the C-oxyalkylation of pyrrole, furan, thiophene, 1,3-thiazole, and 1,2-oxazole derivatives. The re- action conditions and the yields of the corresponding triflu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9de0ced166456e291b8aa1e1f0246fd
https://doi.org/10.1055/s-0029-1218633
https://doi.org/10.1055/s-0029-1218633
Publikováno v:
Synthesis. 2009:1099-1104
The highly electrophilic ketones 2-(trifluoroacetyl)-1,3-diazoles easily undergo a decarboxylative aldol-type reaction with activated acetic acids to afford heterocyclic trifluoromethyl-substituted alcohols bearing various functionalities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66a28b5585a22b5253c283c34a70d431
https://doi.org/10.1055/s-0028-1087985
https://doi.org/10.1055/s-0028-1087985
Autor:
Oleg V. Shishkin, Dmitriy M. Volochnyuk, Pavel V. Khodakovskiy, Alexander Shivanyuk, Andrey A. Tolmachev
Publikováno v:
Synthesis. 2008:3245-3252
2-(Trifluoroacetyl)-1,3-azoles readily react with methyl acrylate and acrylonitrile under Baylis-Hillman reaction conditions to afford heterocyclic trifluoromethyl-containing allylic alcohols in 36-97% yields. The thus obtained Baylis-Hillman adducts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591aa7c4ae4168ce7f35ce2a88b8d021
https://doi.org/10.1055/s-0028-1083150
https://doi.org/10.1055/s-0028-1083150
Autor:
Andrey A. Tolmachev, Pavel V. Khodakovskiy, Sergey V. Ryabukhin, Alexander N. Shivanyuk, Dmitry S. Granat
Publikováno v:
Tetrahedron Letters. 49:3997-4002
New efficient one-pot methodology for the preparative synthesis of β-imidazolylpropionamides was elaborated. It is based on the addition of imidazole to the activated double bond of the intermediate acrylimidazolide in the reaction between diverse a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7165a0e2f4d84ac4c170e28462ea3ca3
https://doi.org/10.1016/j.tetlet.2008.04.096
https://doi.org/10.1016/j.tetlet.2008.04.096