Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Pavel V, Bondarenko"'
Autor:
Daniel W. Woodall, Thomas M. Dillon, Kevin Kalenian, Rupa Padaki, Scott Kuhns, David J. Semin, Pavel V. Bondarenko
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Antibodies facilitate targeted cell killing by engaging with immune cells such as natural killer cells through weak binding interactions with Fcγ receptors on the cell surface. Here, we evaluate the binding affinity of the receptor FcγRIIIa V158 (C
Externí odkaz:
https://doaj.org/article/3d80519d7d5a4b369155036a9e5272d1
Autor:
Pavel V. Bondarenko, Andrew C. Nichols, Gang Xiao, Rachel Liuqing Shi, Pik Kay Chan, Thomas M Dillon, Fernando Garces, David J. Semin, Margaret S. Ricci
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Therapeutic proteins including antibodies and Fc-fusion proteins undergo a large number of chemical modifications during cell culture, purification, storage and in human circulation. They are also exposed to harsh conditions during stress studies, in
Externí odkaz:
https://doaj.org/article/0330ec830a86486d90f0c24ba833c6c6
Autor:
Rachel Liuqing Shi, Gang Xiao, Thomas M. Dillon, Arnold McAuley, Margaret S. Ricci, Pavel V. Bondarenko
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Chemical modifications (attributes) in the binding regions of stressed therapeutic proteins may affect binding to target and efficacy of therapeutic proteins. The method presented here describes the criticality assessment of therapeutic antibody modi
Externí odkaz:
https://doaj.org/article/78a167f61e154861acb1caacdd4ef313
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Recently, cation exchange chromatography (CEX) using aqueous volatile buffers was directly coupled with mass spectrometry (MS) and applied for intact analysis of therapeutic proteins and antibodies. In our study, chemical modifications responsible fo
Externí odkaz:
https://doaj.org/article/9c99e54a1a314a89a461b32fdff38509
Autor:
Chao-Hsiang Wu, Izydor Apostol, Chetan T. Goudar, Pavel V. Bondarenko, Da Ren, Zhongqi Zhang, David J. Semin
Publikováno v:
Current Opinion in Biotechnology. 71:206-215
Rapid technological advances have significantly improved the capability, versatility, and robustness of mass spectrometers which has led to them playing a central role in the development, characterization, and regulatory filings of biopharmaceuticals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85ff12bfaf6d7003c6b7628cc6aac21
https://doi.org/10.1016/j.copbio.2021.08.001
https://doi.org/10.1016/j.copbio.2021.08.001
Publikováno v:
Collection of Scientific Publications NUS. :40-44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab06aea11811de43d1b0d1b85a6972a5
https://doi.org/10.15589/znp2021.4(487).7
https://doi.org/10.15589/znp2021.4(487).7
Autor:
Roman A. Zubarev, Yury O. Tsybin, Catherine E. Costello, Viatcheslav B. Artaev, Pavel V. Bondarenko
Publikováno v:
Journal of the American Society for Mass Spectrometry. 30:2178-2182
The Russian Mass Spectrometry Interest Group (RMSIG) emerged in 1998 during the annual ASMS meeting in Orlando, FL. The original goal of the group was to help assimilating mass spectrometrists from the former Soviet Union countries into the West. Fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d3f824a768322385e707fd0c91d888
https://doi.org/10.1007/s13361-019-02281-9
https://doi.org/10.1007/s13361-019-02281-9
Autor:
Pavel V. Bondarenko, Steven L. Cockrill, Layle K. Watkins, Ingrid D. Cruzado, Ronald D. Macfarlane
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 3, Pp 543-555 (1999)
New isoforms of apolipoprotein (apo)C-I and apoC-III have been detected in delipidated fractions from very low density lipoprotein (VLDL) using matrix-assisted laser desorption (MALDI) and electrospray ionization (ESI) mass spectrometry (MS). The cle
Externí odkaz:
https://doaj.org/article/b8a5616a57ed4f60b68062af82587030
Autor:
Fernando Garces, Thomas M. Dillon, Margaret Speed Ricci, Pik Kay Chan, Andrew C. Nichols, David J. Semin, Rachel Liuqing Shi, Gang Xiao, Pavel V. Bondarenko
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Therapeutic proteins including antibodies and Fc-fusion proteins undergo a large number of chemical modifications during cell culture, purification, storage and in human circulation. They are also exposed to harsh conditions during stress studies, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b989d81194377f71032e9152e19c10
https://doi.org/10.1080/19420862.2021.1887629
https://doi.org/10.1080/19420862.2021.1887629
Publikováno v:
mAbs
Recently, cation exchange chromatography (CEX) using aqueous volatile buffers was directly coupled with mass spectrometry (MS) and applied for intact analysis of therapeutic proteins and antibodies. In our study, chemical modifications responsible fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155aa99f04d97daeaea1216bbb2c10be
http://europepmc.org/articles/PMC7188404
http://europepmc.org/articles/PMC7188404