Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Pavel Strohner"'
1
THE RECOVERY-ELISA—A NOVEL ASSAY TECHNIQUE TO MONITOR THERAPY WITH HUMANIZED ANTIBODIES: THE EXAMPLE OF OMALIZUMAB
Autor: Gunther Becher, Pavel Strohner, Stephanie Korn, Roland Buhl
Publikováno v: Journal of Immunoassay and Immunochemistry. 34:83-93
The therapeutic use of antibodies has grown exponentially, providing new treatment options for various diseases. Monitoring treatment with therapeutic antibodies is a particular challenge because often the target antigen is no longer measurable or th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8886fbb1843d3868975c9786030cdbb
https://doi.org/10.1080/15321819.2012.683501
Zobrazit plný text záznamu
2
Monitoring free serum IgE in severe asthma patients treated with omalizumab
Autor: Gunther Becher, Roland Buhl, Ina Haasler, Stephanie Korn, Florian Fliedner, Antonia Staatz, Pavel Strohner, Christian Taube
Publikováno v: Respiratory Medicine, 106(11), 1494-1500
SummaryBackgroundBenefit of treatment with the monoclonal anti-IgE-antibody omalizumab in severe IgE-dependent asthma requires a significant reduction of serum free IgE concentrations. It is unclear if monitoring free serum IgE is clinically meaningf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fcbef769a718e1ac329b0645acf462f
Zobrazit plný text záznamu
3
The recoveryELISA – a newly developed immunoassay for measurement of therapeutic antibodies and the target antigen during antibody therapy
Autor: Jens-Oliver Steiss, Gunther Becher, Pavel Strohner, Dieter Sarrach, Antonia Staatz
Publikováno v: Clinical Chemistry and Laboratory Medicine (CCLM). 50:1263-1269
Therapeutic antibodies are an important part of Biopharmaceuticals. They are highly innovative and specific drugs. Additionally, they play a challenging role in new demands in diagnostics because they disturb conventional antibody-based tests, such a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fc9029a4b51edd4e9457dbfe10b3af
https://doi.org/10.1515/cclm-2011-0644
Zobrazit plný text záznamu
6
Use of a modified binding model for the investigation of affinity dependence on antibody concentration in immunoassay systems
Autor: Pavel Strohner, Dieter Sarrach, Jens G. Reich
Publikováno v: Journal of Immunological Methods. 203:113-122
Affinity parameters obtained from standard calibration curves of radioimmunoassays (RIA) have been shown to decrease with increasing antibody concentration. A modified binding model was introduced in which not only binding capacity but also affinity
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e527ead59bf2c34c4502954a8de4a5
https://doi.org/10.1016/s0022-1759(97)00022-7
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje