Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Pavel Pitule"'
Autor:
Alena Machuldova, Monika Holubova, Valentina S. Caputo, Miroslava Cedikova, Pavel Jindra, Lucie Houdova, Pavel Pitule
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer cells possess key regulatory function in various malignant diseases, including acute myeloid leukemia. NK cell activity is driven by signals received through ligands binding activating or inhibitory receptors. Their activity towards el
Externí odkaz:
https://doaj.org/article/7f5e4c10b31c466bb224c23b27d3d567
Publikováno v:
Cardiology Research and Practice, Vol 2019 (2019)
Background. Abdominal aortic aneurysms (AAA) are relatively frequent in elderly population, and their ruptures are related with high mortality rate. There are no actually used laboratory markers predicting the AAA development, course, and rupture. Mi
Externí odkaz:
https://doaj.org/article/38e22d75952e4a7eab3b8d16f40692f3
Autor:
Ondrej Fiala, Pavel Pitule, Petr Hosek, Vaclav Liska, Ondrej Sorejs, Jan Bruha, Ondrej Vycital, Tomas Buchler, Alexandr Poprach, Ondrej Topolcan, Jindrich Finek
Publikováno v:
Tumor Biology, Vol 39 (2017)
MicroRNAs regulate the expression of genes involved in several important cancer-related processes including cell adhesion, proliferation, and tumour angiogenesis. Bevacizumab is routinely used in the treatment of patients with metastatic colorectal c
Externí odkaz:
https://doaj.org/article/34c94327aacb4e9b9990be84d478dbdd
Autor:
Miroslava Cedikova, Michaela Kripnerová, Jana Dvorakova, Pavel Pitule, Martina Grundmanova, Vaclav Babuska, Dana Mullerova, Jitka Kuncova
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Mitochondria play a key role in energy metabolism in many tissues, including cardiac and skeletal muscle, brain, liver, and adipose tissue. Three types of adipose depots can be identified in mammals, commonly classified according to their colour appe
Externí odkaz:
https://doaj.org/article/7279a901db4f4454936a6173c50197ef
Autor:
Drahomír Kolenčík, Sachin Narayan, Jana-Aletta Thiele, Dillon McKinley, Anna Sandström Gerdtsson, Lisa Welter, Petr Hošek, Pavel Ostašov, Ondřej Vyčítal, Jan Brůha, Ondřej Fiala, Ondřej Šorejs, Václav Liška, Pavel Pitule, Peter Kuhn, Stephanie N. Shishido
Publikováno v:
Cancers; Volume 14; Issue 3; Pages: 642
Cancers, Vol 14, Iss 642, p 642 (2022)
Cancers, Vol 14, Iss 642, p 642 (2022)
The liquid biopsy has the potential to improve current clinical practice in oncology by providing real-time personalized information about a patient’s disease status and response to treatment. In this study, we evaluated 161 peripheral blood (PB) s
Autor:
Pavel Pitule, James W. Hicks, Stephanie N. Shishido, Peter Kuhn, Jeremy Mason, Drahomír Kolenčík
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1376, p 1376 (2020)
Cancers, Vol 12, Iss 1376, p 1376 (2020)
Colorectal carcinoma (CRC) is characterized by wide intratumor heterogeneity with general genomic instability and there is a need for improved diagnostic, prognostic, and therapeutic tools. The liquid biopsy provides a noninvasive route of sample col
Autor:
Pavel Pitule, Ursula Altanerova, Martina Zduriencikova, Vanda Repiská, Jana Jakubechova, Katarina Benejova, J Kausitz, Martin Pesta, Petra Priscakova, Cestmir Altaner, Ondrej Topolcan
Publikováno v:
International Journal of Cancer. 144:897-908
The natural behavior of mesenchymal stem cells (MSCs) and their exosomes in targeting tumors is a promising approach for curative therapy. Human tumor tropic mesenchymal stem cells (MSCs) isolated from various tissues and MSCs engineered to express t
Autor:
Jiří Polívka, Martin Pešta, Pavel Pitule, Ondřej Hes, Luboš Holubec, Tereza Kubíková, Zbyněk Tonar
Publikováno v:
Oncotarget
// Jiři Polivka Jr 1, 2, 3 , Martin Pesta 2, 4 , Pavel Pitule 1, 2 , Ondřej Hes 5 , Lubos Holubec 2 , Jiři Polivka 3 , Tereza Kubikova 1, 2 and Zbyněk Tonar 1, 2 1 Department of Histology and Embryology, Charles University, Faculty of Medicine in
Autor:
Filip Tichanek, Martina Salomova, Jan Jedlicka, Jitka Kuncova, Pavel Pitule, Tereza Macanova, Zuzana Petrankova, Zdenek Tuma, Jan Cendelin
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Spinocerebellar ataxia 1 (SCA1) is a devastating neurodegenerative disease associated with cerebellar degeneration and motor deficits. However, many patients also exhibit neuropsychiatric impairments such as depression and apathy; nevertheless, the e
Publikováno v:
Anticancer research. 39(11)
BACKGROUND/AIM Treatment of colorectal cancer (CRC) does not reflect immune interactions between tumours and macro-organisms. Serpin B9 is known as an inhibitor of Granzyme B. The aim of this study was to evaluate the impact of the expression of Serp