Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Pavel Ostasov"'
1
Akademický článek
The Expression Profile of MicroRNAs in Small and Large Abdominal Aortic Aneurysms
Autor: Václava Černá, Pavel Ostašov, Pavel Pitule, Jiří Moláček, Vladislav Třeška, Martin Pešta
Publikováno v: Cardiology Research and Practice, Vol 2019 (2019)
Background. Abdominal aortic aneurysms (AAA) are relatively frequent in elderly population, and their ruptures are related with high mortality rate. There are no actually used laboratory markers predicting the AAA development, course, and rupture. Mi
Externí odkaz: https://doaj.org/article/38e22d75952e4a7eab3b8d16f40692f3
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2
Akademický článek
Evolution of Advanced Chronic Lymphoid Leukemia Unveiled by Single-Cell Transcriptomics: A Case Report
Autor: Pavel Ostasov, Henry Robertson, Paolo Piazza, Avik Datta, Jane Apperley, Lucie Houdova, Daniel Lysak, Monika Holubova, Katerina Tesarova, Valentina S. Caputo, Iros Barozzi
Publikováno v: Frontiers in Oncology, Vol 10 (2020)
Genetic and transcriptional heterogeneity of Chronic lymphocytic leukaemia (CLL) limits prevention of disease progression. Longitudinal single-cell transcriptomics represents the state-of-the-art method to profile the disease heterogeneity at diagnos
Externí odkaz: https://doaj.org/article/aa9fd42a7eec4cb5bc9c63eda042ba23
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4
Impact of Concomitant Cardiovascular Medication on Survival of Metastatic Renal Cell Carcinoma Patients Treated with Sunitinib or Pazopanib in the First Line
Autor: Milan Hora, Tomas Buchler, Jan Filipovský, Pavel Ostasov, Ivan Trávníček, Barbora Bendová, Jan Šustr, Jindřich Fínek, Aneta Rozsypalova, Ondřej Šorejs, Ondřej Fiala
Publikováno v: Targeted Oncology. 16:643-652
Patients with metastatic renal cell carcinoma (mRCC) are often elderly and have various comorbidities, including cardiovascular diseases. Although these patients have extensive co-exposure to targeted therapy and cardiovascular drugs, the impact of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1e87e7cdac15521ef4cd8a1faf683d
https://doi.org/10.1007/s11523-021-00829-y
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5
Single-Nucleotide Polymorphisms in MICA and MICB Genes Could Play a Role in the Outcome in AML Patients after HSCT
Autor: Pavel Ostasov, Diana Maceckova, Hana Gmucova, Katerina Kratochvilova, Jiri Sramek, Alena Machuldova, Robin Klieber, Monika Holubova, Pavel Jindra, Martin Leba, Lucie Houdová
Publikováno v: Journal of Clinical Medicine, Vol 10, Iss 4636, p 4636 (2021)
Journal of Clinical Medicine
Volume 10
Issue 20
NKG2D and its ligands, MICA and MICB, are known as the key regulators of NK cells. NK cells are the first reconstituted cells after the allogeneic hematopoietic stem cell transplantation (HSCT)
therefore, it is crucial to understand their role i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416d6cc481560aa16fac9164ac4827f0
https://www.mdpi.com/2077-0383/10/20/4636
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6
Spatial expression pattern of serine proteases in the blood fluke Schistosoma mansoni determined by fluorescence RNA in situ hybridization
Autor: Pavel Ostasov, Jan Dvořák, Michael Mareš, Martin Horn, Lenka Ulrychová, Marta Chanová
Publikováno v: Parasites & Vectors
Parasites & Vectors, Vol 14, Iss 1, Pp 1-14 (2021)
Background The blood flukes of genus Schistosoma are the causative agent of schistosomiasis, a parasitic disease that infects more than 200 million people worldwide. Proteases of schistosomes are involved in critical steps of host–parasite interact
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb1d29e58241b33482341b49d251039
https://pubmed.ncbi.nlm.nih.gov/34022917
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7
Role of genetic variation in cytochromes P450 in breast cancer prognosis and therapy response
Autor: Pavel Soucek, Viktor Hlavac, Katerina Kopeckova, Pavel Ostasov, Radka Vaclavikova, Jiří Gatěk, Renata Koževnikovová, Veronika Brynychova, David Vrána
Publikováno v: International journal of molecular sciences
International Journal of Molecular Sciences
Volume 22
Issue 6
International Journal of Molecular Sciences, Vol 22, Iss 2826, p 2826 (2021)
Breast cancer is the most frequent cancer in the female population worldwide. The role of germline genetic variability in cytochromes P450 (CYP) in breast cancer prognosis and individualized therapy awaits detailed elucidation. In the present study,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07b7ea89be65dd1ce98291e56c40ee7
http://publikace.k.utb.cz/handle/10563/1010294
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8
Incidental Use of Beta-Blockers Is Associated with Outcome of Metastatic Colorectal Cancer Patients Treated with Bevacizumab-Based Therapy: A Single-Institution Retrospective Analysis of 514 Patients
Autor: Ondrej, Fiala, Pavel, Ostasov, Ondrej, Sorejs, Vaclav, Liska, Tomas, Buchler, Alexandr, Poprach, Jindrich, Finek
Publikováno v: Cancers
Background: Beta-adrenergic signalling plays an important role in several cancer-related processes, including angiogenesis. The impact of beta-blocker use on prognosis of cancer patients treated with antiangiogenic agents is unclear. The aim of this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b284ea40f28bfdfe6c3d290f51dd81b
https://pubmed.ncbi.nlm.nih.gov/31769417
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9
The Predictive Role of Primary Tumour Sidedness in Metastatic Colorectal Cancer Treated With Targeted Agents
Autor: Ondrej Sorejs, Petr Hosek, Jan Šustr, Ondrej Topolcan, Jindrich Finek, Radek Kucera, Pavel Ostasov, Vaclav Liska, Ondrej Fiala, Tomas Buchler, Monika Sedivcova, Alexandr Poprach
Publikováno v: Anticancer research. 39(10)
BACKGROUND/AIM The aim of our study was to assess the predictive role of primary tumour sidedness (PTS) in patients with metastatic colorectal cancer (mCRC) harbouring wild-type RAS and treated with targeted agents. PATIENTS AND METHODS The cohort in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787ecd3d8ff496a8be23b9842de0ded0
https://pubmed.ncbi.nlm.nih.gov/31570462
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10
lncRNAs in Non-Malignant Tissue Have Prognostic Value in Colorectal Cancer
Autor: Jana-Aletta Thiele, Petr Hosek, Eva Kralovcova, Pavel Ostasov, Vaclav Liska, Jan Bruha, Ondrej Vycital, Jachym Rosendorf, Alena Opattova, Josef Horak, Milena Kralickova, Pavel Vodicka, Pavel Pitule
Publikováno v: International Journal of Molecular Sciences
Volume 19
Issue 9
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2672 (2018)
Although colorectal cancer (CRC) is the third most frequent cause of cancer related death in Europe, clinically relevant biomarkers for therapy guidance and prognosis are insufficiently reliable. Long non-coding RNAs (lncRNAs) are RNAs over 200 nucle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9c1b4c44c628de240028ac2280578d87
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