Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pavel O. Vorobyev"'
Autor:
Olga N. Ivanova, Anna V. Gavlina, Inna L. Karpenko, Martin A. Zenov, Svetlana S. Antseva, Natalia F. Zakirova, Vladimir T. Valuev-Elliston, George S. Krasnov, Irina T. Fedyakina, Pavel O. Vorobyev, Birke Bartosch, Sergey N. Kochetkov, Anastasiya V. Lipatova, Dmitry V. Yanvarev, Alexander V. Ivanov
Publikováno v:
Cells, Vol 13, Iss 13, p 1134 (2024)
Biogenic polyamines are ubiquitous compounds. Dysregulation of their metabolism is associated with the development of various pathologies, including cancer, hyperproliferative diseases, and infections. The canonical pathway of polyamine catabolism in
Externí odkaz:
https://doaj.org/article/e2310228fff64a8eabd12fc2d6a9d26e
Autor:
Yasmin Shakiba, Pavel O. Vorobyev, Gaukhar M. Yusubalieva, Dmitry V. Kochetkov, Ksenia V. Zajtseva, Marat P. Valikhov, Vladimir A. Kalsin, Fedor G. Zabozlaev, Alevtina S. Semkina, Alexander V. Troitskiy, Vladimir P. Baklaushev, Peter M. Chumakov, Anastasia V. Lipatova
Publikováno v:
Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 158-168 (2023)
We developed recombinant variants of oncolytic vaccinia virus LIVP strain expressing interleukin-15 (IL-15) or its receptor subunit alpha (IL-15Rα) to stimulate IL-15-dependent immune cells. We evaluated their oncolytic activity either alone or in c
Externí odkaz:
https://doaj.org/article/73285d776e75402d96cc8f488cd8119f
Autor:
Yasmin Shakiba, Pavel O. Vorobyev, Victor A. Naumenko, Dmitry V. Kochetkov, Ksenia V. Zajtseva, Marat P. Valikhov, Gaukhar M. Yusubalieva, Yana D. Gumennaya, Egor A. Emelyanov, Alevtina S. Semkina, Vladimir P. Baklaushev, Peter M. Chumakov, Anastasia V. Lipatova
Publikováno v:
Viruses, Vol 15, Iss 4, p 828 (2023)
Oncolytic viral therapy is a promising novel approach to cancer treatment. Oncolytic viruses cause tumor regression through direct cytolysis on the one hand and recruiting and activating immune cells on the other. In this study, to enhance the antitu
Externí odkaz:
https://doaj.org/article/2d5b951c014846d197ddcf88c5251610
Autor:
Olga A. Smirnova, Olga N. Ivanova, Irina T. Fedyakina, Gaukhar M. Yusubalieva, Vladimir P. Baklaushev, Dmitry V. Yanvarev, Olga I. Kechko, Vladimir A. Mitkevich, Pavel O. Vorobyev, Vyacheslav S. Fedorov, Birke Bartosch, Vladimir T. Valuev-Elliston, Anastasiya L. Lipatova, Alexander V. Ivanov
Publikováno v:
Cancers, Vol 15, Iss 3, p 632 (2023)
Severe acute respiratory syndrome associated coronavirus 2 (SARS-CoV-2) emerged at the end of 2019 and rapidly caused a pandemic that led to the death of >6 million people due to hypercoagulation and cytokine storm. In addition, SARS-CoV-2 triggers a
Externí odkaz:
https://doaj.org/article/dd8e3192b6ac4ad2b3f77a5faabdbc2e
Autor:
Pavel O. Vorobyev, Dmitry V. Kochetkov, Peter M. Chumakov, Natalia F. Zakirova, Sofia I. Zotova-Nefedorova, Konstantin V. Vasilenko, Olga N. Alekseeva, Sergey N. Kochetkov, Birke Bartosch, Anastasiya V. Lipatova, Alexander V. Ivanov
Publikováno v:
Cancers, Vol 14, Iss 22, p 5611 (2022)
Glioblastoma multiforme (GBM) is one of the most common types of brain tumor. Despite intensive research, patients with GBM have a poor prognosis due to a very high rate of relapse and significant side effects of the treatment, with a median survival
Externí odkaz:
https://doaj.org/article/0e9a2224bf2648ad972f6b5d3ee43697
Autor:
Anastasia S. Nikitina, Anastasia V. Lipatova, Anton O. Goncharov, Anna A. Kliuchnikova, Mikhail A. Pyatnitskiy, Ksenia G. Kuznetsova, Azzam Hamad, Pavel O. Vorobyev, Olga N. Alekseeva, Marah Mahmoud, Yasmin Shakiba, Ksenia S. Anufrieva, Georgy P. Arapidi, Mark V. Ivanov, Irina A. Tarasova, Mikhail V. Gorshkov, Peter M. Chumakov, Sergei A. Moshkovskii
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5244 (2022)
Cancer cell lines responded differentially to type I interferon treatment in models of oncolytic therapy using vesicular stomatitis virus (VSV). Two opposite cases were considered in this study, glioblastoma DBTRG-05MG and osteosarcoma HOS cell lines
Externí odkaz:
https://doaj.org/article/c684fc2217df4b81b868e2f7b8b6f803
Autor:
Anastasiya V. Lipatova, Alesya V. Soboleva, Vladimir A. Gorshkov, Julia A. Bubis, Elizaveta M. Solovyeva, George S. Krasnov, Dmitry V. Kochetkov, Pavel O. Vorobyev, Irina Y. Ilina, Sergei A. Moshkovskii, Frank Kjeldsen, Mikhail V. Gorshkov, Peter M. Chumakov, Irina A. Tarasova
Publikováno v:
Cancers, Vol 13, Iss 21, p 5268 (2021)
Oncolytic viruses have gained momentum in the last decades as a promising tool for cancer treatment. Despite the progress, only a fraction of patients show a positive response to viral therapy. One of the key variable factors contributing to therapy
Externí odkaz:
https://doaj.org/article/97c40ff905664ac59bc9aa6d36901984