Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pavel Nedvetsky"'
Autor:
Simona Mareike Lüttgenau, Christin Emming, Thomas Wagner, Julia Harms, Justine Guske, Katrin Weber, Ute Neugebauer, Rita Schröter, Olga Panichkina, Zoltán Pethő, Florian Weber, Albrecht Schwab, Anja Kathrin Wege, Pavel Nedvetsky, Michael P. Krahn
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-7 (2021)
Abstract Loss of apical-basal polarity and downregulation of cell-cell contacts is a critical step during the pathogenesis of cancer. Both processes are regulated by the scaffolding protein Pals1, however, it is unclear whether the expression of Pals
Externí odkaz:
https://doaj.org/article/2474a5be80114ad884671a3f42dd5a01
Autor:
Sarah Borkowsky, Maximilian Gass, Azadeh Alavizargar, Johannes Hanewinkel, Ina Hallstein, Pavel Nedvetsky, Andreas Heuer, Michael P. Krahn
Publikováno v:
Cells, Vol 12, Iss 5, p 812 (2023)
The master kinase LKB1 is a key regulator of se veral cellular processes, including cell proliferation, cell polarity and cellular metabolism. It phosphorylates and activates several downstream kinases, including AMP-dependent kinase, AMPK. Activatio
Externí odkaz:
https://doaj.org/article/8fe14c4979fd486bb1938d6bb8414c84
Autor:
Xiaocheng Zhao, Pavel Nedvetsky, Fabio Stanchi, Anne-Clemence Vion, Oliver Popp, Kerstin Zühlke, Gunnar Dittmar, Enno Klussmann, Holger Gerhardt
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/f50788c63ebb4063b63669ca3c6bad5e
Autor:
Xiaocheng Zhao, Pavel Nedvetsky, Fabio Stanchi, Anne-Clemence Vion, Oliver Popp, Kerstin Zühlke, Gunnar Dittmar, Enno Klussmann, Holger Gerhardt
Publikováno v:
eLife, Vol 8 (2019)
The cAMP-dependent protein kinase A (PKA) regulates various cellular functions in health and disease. In endothelial cells PKA activity promotes vessel maturation and limits tip cell formation. Here, we used a chemical genetic screen to identify endo
Externí odkaz:
https://doaj.org/article/d866cab8e84a4592975aa952d912b1a6
Autor:
Ann-Christin Groh, Simon Kleimann, Pavel Nedvetsky, Malina Behrens, Annika Möller-Kerutt, Verena Höffken, Sujasha Ghosh, Uwe Hansen, Michael P. Krahn, Alexander Ludwig, Klaus Ebnet, Hermann Pavenstädt, Thomas Weide
The evolutionarily conserved Crumbs (CRB) polarity complex, which consists of the core components CRB3a, PALS1 and PATJ, plays a key role in epithelial cell-cell contact formation and cell polarization. Recently we observed that deletion of onePals1a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8566079ab0b706ec0f1fff8dc50ee6c4
https://doi.org/10.1101/2023.04.27.538411
https://doi.org/10.1101/2023.04.27.538411
Autor:
Julia Harms, Simona Mareike Lüttgenau, Christin Emming, Justine Guske, Katrin Weber, Thomas Wagner, Larissa Schowe, Pavel Nedvetsky, Michael P. Krahn
Publikováno v:
Cancer gene therapy.
Downregulation of cell–cell adhesion and increased motility are prerequisites for the metastasis of cancer cells. We have recently shown that downregulation of the tight junction adapter protein Pals1 in colorectal cancer cells results in an increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd801fc5f780c2efb2fae21d99bf6ec
https://pubmed.ncbi.nlm.nih.gov/36494580
https://pubmed.ncbi.nlm.nih.gov/36494580
Autor:
Maximilian M. Gass, Sarah Borkowsky, Marie-Luise Lotz, Rebecca Siwek, Rita Schröter, Pavel Nedvetsky, Stefan Luschnig, Astrid Rohlmann, Markus Missler, Michael P. Krahn
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(5)
Drosophila nephrocytes are an emerging model system for mammalian podocytes and proximal tubules as well as for the investigation of kidney diseases. Like podocytes, nephrocytes exhibit characteristics of epithelial cells, but the role of phospholipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee8e397139a9c58b2136bca0b3ec383
https://pubmed.ncbi.nlm.nih.gov/35437696
https://pubmed.ncbi.nlm.nih.gov/35437696
Autor:
Xiaocheng Zhao, Pavel Nedvetsky, Fabio Stanchi, Anne-Clemence Vion, Oliver Popp, Kerstin Zühlke, Gunnar Dittmar, Enno Klussmann, Holger Gerhardt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0c1e77c1b4e2e04f8a17fb597bed25
https://doi.org/10.7554/elife.46380.022
https://doi.org/10.7554/elife.46380.022