Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Pavel Mazanek"'
Autor:
Kristyna Polaskova, Tomas Merta, Alexandra Martincekova, Danica Zapletalova, Michal Kyr, Pavel Mazanek, Zdenka Krenova, Peter Mudry, Marta Jezova, Jiri Tuma, Jarmila Skotakova, Ivana Cervinkova, Dalibor Valik, Lenka Zdrazilova-Dubska, Hana Noskova, Karol Pal, Ondrej Slaby, Pavel Fabian, Sarka Kozakova, Jakub Neradil, Renata Veselska, Veronika Kanderova, Ondrej Hrusak, Tomas Freiberger, Giannoula Lakka Klement, Jaroslav Sterba
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
In order to identify reasons for treatment failures when using targeted therapies, we have analyzed the comprehensive molecular profiles of three relapsed, poor-prognosis Burkitt lymphoma cases. All three cases had resembling clinical presentation an
Externí odkaz:
https://doaj.org/article/5c281799cb3e41e29ab698bc35a5380e
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract For decades, retinoids and their synthetic derivatives have been well established anticancer treatments due to their ability to regulate cell growth and induce cell differentiation and apoptosis. Many studies have reported the promising role
Externí odkaz:
https://doaj.org/article/2079bfc87e0544c68564cd815a548ef1
Autor:
Renata Veselska, Marta Jezova, Michal Kyr, Pavel Mazanek, Petr Chlapek, Viera Dobrotkova, Jaroslav Sterba
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The survival rate for patients with high-risk neuroblastomas remains poor despite new improvements in available therapeutic modalities. A detailed understanding of the mechanisms underlying clinical responses to multimodal treatment is one of the imp
Externí odkaz:
https://doaj.org/article/cc77f362613344c78f1a26281eb21144
Autor:
Lenka Fedorova, Peter Mudry, Katerina Pilatova, Iveta Selingerova, Jana Merhautova, Zdenek Rehak, Dalibor Valik, Eva Hlavackova, Dasa Cerna, Lucie Faberova, Pavel Mazanek, Zdenek Pavelka, Regina Demlova, Jaroslav Sterba, Lenka Zdrazilova-Dubska
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Monocyte-derived dendritic cell (DC)-based vaccines loaded with tumor self-antigens represent a novel approach in anticancer therapy. We evaluated DC-based anticancer immunotherapy (ITx) in an academic Phase I/II clinical trial for children, adolesce
Externí odkaz:
https://doaj.org/article/c3ae2baabd0d44bdbcc5b4dc91aed1c5
Autor:
Eva Hlavackova, Katerina Pilatova, Dasa Cerna, Iveta Selingerova, Peter Mudry, Pavel Mazanek, Lenka Fedorova, Jana Merhautova, Lucie Jureckova, Lukas Semerad, Rita Pacasova, Lucie Flajsarova, Lenka Souckova, Regina Demlova, Jaroslav Sterba, Dalibor Valik, Lenka Zdrazilova-Dubska
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Despite efforts to develop novel treatment strategies, refractory and relapsing sarcoma, and high-risk neuroblastoma continue to have poor prognoses and limited overall survival. Monocyte-derived dendritic cell (DC)-based anti-cancer immunotherapy re
Externí odkaz:
https://doaj.org/article/b8aa3e5810634c64ad140ad8ad5c431a
Autor:
Viera Dobrotkova, Petr Chlapek, Marta Jezova, Katerina Adamkova, Pavel Mazanek, Jaroslav Sterba, Renata Veselska
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218269 (2019)
Although the administration of retinoids represents an important part of treatment for children suffering from high-risk neuroblastomas, approximately 50% of these patients do not respond to this therapy or develop resistance to retinoids during trea
Externí odkaz:
https://doaj.org/article/19d36be6682b4ff194fe653d7664d815
Publikováno v:
BMC Cancer, Vol 6, Iss 1, p 177 (2006)
BMC Cancer
BMC Cancer
Background Neuroblastoma is a frequently lethal pediatric cancer in which MYCN genomic amplification is highly correlated with aggressive disease. Deregulated MYC genes require co-operative lesions to foster tumourigenesis and both direct and indirec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bb8a4b2bb4df34699b8445499c9b36
http://www.biomedcentral.com/1471-2407/6/177
http://www.biomedcentral.com/1471-2407/6/177