Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Pavel Mares"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1296 (2024)
The aim of the present study was to analyze the location of degenerating neurons in the dorsal (insular) claustrum (DCL, VCL) and the dorsal, intermediate and ventral endopiriform nucleus (DEn, IEn, VEn) in rat pups following lithium–pilocarpine st
Externí odkaz:
https://doaj.org/article/c60c4d2edbd746dab444b25996f4cafb
Autor:
Stéphane Auvin, Blandine Dozières‐Puyravel, Andreja Avbersek, David Sciberras, Jo Collier, Karine Leclercq, Pavel Mares, Rafal M. Kaminski, Pierandrea Muglia
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 3, Pp 343-352 (2020)
Abstract Objective Infantile spasm syndrome (ISS) is an epileptic encephalopathy without established treatment after the failure to standard of care based on steroids and vigabatrin. Converging lines of evidence indicating a role of NR2B subunits of
Externí odkaz:
https://doaj.org/article/6e28defa096e430da2342590d5729c98
Autor:
Eva Kudova, Pavel Mares, Martin Hill, Katerina Vondrakova, Grygoriy Tsenov, Hana Chodounska, Hana Kubova, Karel Vales
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 49 (2021)
Pregnanolone glutamate (PA-G) is a neuroactive steroid that has been previously demonstrated to be a potent neuroprotective compound in several biological models in vivo. Our in vitro experiments identified PA-G as an inhibitor of N-methyl-D-aspartat
Externí odkaz:
https://doaj.org/article/421a4e406dcf4dc3bc8960197d4845d4
Autor:
Petr Fabera, Martina Parizkova, Libor Uttl, Katerina Vondrakova, Hana Kubova, Grygoriy Tsenov, Pavel Mares
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Objective: The adenosinergic system may influence excitability in the brain. Endogenous and exogenous adenosine has anticonvulsant activity presumably by activating A1 receptors. Adenosine A1 receptor agonist 2-chloro-N6-cyclopentyladenosine (CCPA) m
Externí odkaz:
https://doaj.org/article/e0f5a74ca8604ea485ba9c41551d0602
Publikováno v:
Pharmaceutics, Vol 13, Iss 3, p 415 (2021)
The GluN2A subunit of N-methyl-D-aspartate (NMDA) receptors becomes dominant during postnatal development, overgrowing the originally dominant GluN2B subunit. The aim of our study was to show changes of anticonvulsant action of the GluN2A subunit-pre
Externí odkaz:
https://doaj.org/article/8d2f9ceb580045338685714987a762e9
Autor:
Pavel Mareš, Jana Veselá
Publikováno v:
Research and Review Journal of Nondestructive Testing, Vol 1, Iss 1 (2023)
Welded joints on various pipelines, especially steam pipelines of fossil power plants, are exposed to high pressure and temperature of steam during operation. The applied stress and temperature together with the chemical composition and microstructur
Externí odkaz:
https://doaj.org/article/b4dc0275aa1a4693941ea50e97351d88
Publikováno v:
Research and Review Journal of Nondestructive Testing, Vol 1, Iss 1 (2023)
Increasing requirements to minimize the frequency and duration of shutdowns of nuclear power plants have led to the need to address the implementation of ultrasonic testing of welded pipe connections at operating temperature. In practice, the pipes a
Externí odkaz:
https://doaj.org/article/e8031026ce5544cbae78c8ad7c1ea6a0
Autor:
Pavel Mares
Publikováno v:
Journal of Modern Physics. :1167-1172
Ultrasonic testing is a very important non-destructive method for testing components for safety of nuclear power plants and other security and delicate parts in other industries. Nowadays, thanks to the development of computer technology, it is possi
Publikováno v:
Epilepsia Open, Vol 8, Iss S1, Pp S90-S109 (2023)
Abstract Status epilepticus (SE) is the most common neurologic emergency in children. Both clinical and laboratory studies have demonstrated that SE in early life can cause brain damage and permanent behavioral abnormalities, trigger epileptogenesis,
Externí odkaz:
https://doaj.org/article/0df19a0c69fe450cabe69e9c30502075
Autor:
Pavel Mareš, Libor Uttl, Martina Laczó, Zina BenSalem, Kateřina Vondráková, Petr Fábera, Grygoriy Tsenov, Hana Kubová
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1733 (2023)
Background: Postictal refractoriness, i.e., the inability to elicit a new epileptic seizure immediately after the first one, is present in mature animals. Immature rats did not exhibit this refractoriness, and it is replaced by postictal potentiation
Externí odkaz:
https://doaj.org/article/4c55e2e8965b484fbeeb9dc76f834db7