Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Pavel M, Vassiliev"'
Autor:
Olga N. Zhukovskaya, Natalya V. Eliseeva, Pavel M. Vassiliev, Gleb V. Pridvorov, Olesya Yu. Grechko, Anatoly S. Morkovnik, Alexander A. Spasov
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 2, Pp 119-133 (2024)
Introduction: The creation of new opioid analgesics that are devoid of the main undesirable effects – euphoria, respiratory depression, tolerance – is an important task for the treatment of pain syndrome. Eighteen salts of 9-pyrrolidinoethyl-(1a)
Externí odkaz:
https://doaj.org/article/16cc6b6bf0cf4b1b9e72fe962ebf69f9
Autor:
Dmitry S. Yakovlev, Pavel M. Vassiliev, Yana V. Agatsarskaya, Anastasia A. Brigadirova, Kira T. Sultanova, Maria O. Skripka, Alexander A. Spasov, Konstantin V. Savateev, Vladimir L. Rusinov, Dmitriy V. Maltsev
Publikováno v:
Research Results in Pharmacology, Vol 8, Iss 2, Pp 69-75 (2022)
Introduction: Ligands of adenosine A1Rs are potential candidates for the development of drugs for the treatment of paroxysmal supraventricular tachycardia, angina pectoris, hypertriglyceridemia, type 2 diabetes mellitus, neuropathic pain, and heart f
Externí odkaz:
https://doaj.org/article/7924b960ea9043d3a35444ae2f8b4398
Autor:
Tatyana A. Stroganova, Vladimir K. Vasilin, Victor V. Dotsenko, Nicolai A. Aksenov, Pavel G. Morozov, Pavel M. Vassiliev, Vitaly A. Volynkin, Gennady D. Krapivin
Publikováno v:
ACS Omega, Vol 6, Iss 22, Pp 14030-14048 (2021)
Externí odkaz:
https://doaj.org/article/b8d106e742c54336b3fb5949d230a0dc
Autor:
Pavel M. Vassiliev, Dmitriy V. Maltsev, Alexander A. Spasov, Maxim A. Perfilev, Maria O. Skripka, Andrey N. Kochetkov
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 731 (2023)
A classification consensus ensemble multitarget neural network model of the dependence of the anxiolytic activity of chemical compounds on the energy of their docking in 17 biotargets was developed. The training set included compounds thathadalready
Externí odkaz:
https://doaj.org/article/f287a3a0ed3440419cce0948df39e7b2
Autor:
Dmitriy V. Maltsev, Alexander A. Spasov, Pavel M. Vassiliev, Maria O. Skripka, Mikhail V. Miroshnikov, Andrey N. Kochetkov, Nataliya V. Eliseeva, Yuliya V. Lifanova, Tatyana A. Kuzmenko, Lyudmila N. Divaeva, Anatolii S. Morkovnik
Publikováno v:
Molecules, Vol 26, Iss 19, p 6049 (2021)
A number of novel 2,3,4,5-tetrahydro[1,3]diazepino[1,2-a]benzimidazole derivatives 2 were obtained by alkylation mainly in the 1H-tautomeric form of 2,3,4,5-tetrahydro[1,3]diazepino[1,2-a]benzimidazole or its 8,9-dimethyl-substituted analog 4-chlorob
Externí odkaz:
https://doaj.org/article/b5318cd03f504802b4cf0d7fdff8c827
Autor:
Dmitriy V, Maltsev, Maria O, Skripka, Alexander A, Spasov, Pavel M, Vassiliev, Maxim A, Perfiliev, Lyudmila N, Divaeva, Alexander A, Zubenko, Anatolii S, Morkovnik, Alexander I, Klimenko, Mikhail V, Miroshnikov, Vladlen G, Klochkov, Laura R, Ianalieva
Publikováno v:
International journal of molecular sciences. 23(22)
A new series of quinoxaline derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41824aa67e6a31d1626ba0d752e020e6
https://pubmed.ncbi.nlm.nih.gov/36430878
https://pubmed.ncbi.nlm.nih.gov/36430878
Autor:
Victor V. Dotsenko, Pavel M. Vassiliev, P. G. Morozov, Vladimir K. Vasilin, Gennady D. Krapivin, V. A. Volynkin, Nicolai A. Aksenov, Tatyana A. Stroganova
Publikováno v:
ACS Omega, Vol 6, Iss 22, Pp 14030-14048 (2021)
ACS Omega
ACS Omega
Noncatalyzed, regio- and stereoselective hypochlorite oxidation of 3-aminothieno[2,3-b]pyridine-2-carboxamides is presented. Unexpectedly, the oxidation proceeded by different mechanistic pathways, and different products were formed, depending on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13b224d030feba57b3faa5fe00cd964
https://doaj.org/article/b8d106e742c54336b3fb5949d230a0dc
https://doaj.org/article/b8d106e742c54336b3fb5949d230a0dc
Publikováno v:
Russian Chemical Bulletin. 70:562-566
Five scaffolds (phenoxybenzene, benzofuran, azolobenzimidazole, oxoindole, and uracil), which are promising as sources of compounds with high RAGE inhibitory activity, were found in silico among ten structurally different classes of the synthesized s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b86df5d7ffc8e583acf352533ac92cc
https://doi.org/10.1007/s11172-021-3125-3
https://doi.org/10.1007/s11172-021-3125-3
Autor:
Gennady D. Krapivin, Pavel M. Vassiliev, Tat’yana А. Stroganova, Eugeniya A. Kanishcheva, Vladimir K. Vasilin, Anzhelika V. Gizhinskaya, Vitaly А. Volynkin
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:1078-1091
3-Azido-4,6-diarylthienopyridines obtained from the corresponding 3-amino derivatives are convenient precursors in the synthesis of the peri-annulated heterocyclic system, benzo(furo,thieno)[c]thieno[2,3,4-i,j]-2,7-naphthyridines. The spectral charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63dcc081bd416f173fd2ae274d3c8685
https://doi.org/10.1007/s10593-020-02777-3
https://doi.org/10.1007/s10593-020-02777-3
Autor:
S. G. Tolschina, A. F. Kucheryavenko, Rashida I. Ishmetova, V. A. Babkova, Pavel M. Vassiliev, N. K. Ignatenko, Alexander A. Spasov, Denis A. Babkov, G. L. Rusinov, V. S. Sirotenko
Publikováno v:
Russian Chemical Bulletin. 69:768-773
According to the in silico consensus activity prediction, a series of 3,6-disubstituted 1,2,4,5-tetrazines were synthesized as promising inhibitors of the Maillard reaction. In addition to the studies of antiglycation activity, a comparative in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0138320c146648c15f1983fb7fa6ec17
https://doi.org/10.1007/s11172-020-2831-6
https://doi.org/10.1007/s11172-020-2831-6