Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pavel Kuneš"'
Autor:
Jan Krejsek, Martina Koláčková, Jiří Manďák, Pavel Kuneš, Zdeňka Holubcová, Drahomíra Holmannová, Mouhammed AbuAttieh, Ctirad Andrýs
Publikováno v:
Acta Medica, Vol 56, Iss 2, Pp 57-66 (2013)
Cardiac surgery is inseparably linked to the activation of innate immunity cells recognizing danger signals of both endogenous and exogenous origin via pattern recognition receptors such as TLR receptors. Therefore, we followed by flow cytometry TLR2
Externí odkaz:
https://doaj.org/article/7023b19cf0a04502b39cbe1bdac11135
Autor:
Drahomíra Holmannová, Martina Koláčková, Kateřina Kondělková, Pavel Kuneš, Jan Krejsek, Ctirad Andrýs
Publikováno v:
Acta Medica, Vol 55, Iss 2, Pp 59-65 (2012)
CD200 and its receptor were recognized as having the multiple immunoregulatory functions. Their immunoregulatory, suppressive, and tolerogenic potentials could be very effectively exploited in the treatment of many diseases, e.g. Alzheimer disease, r
Externí odkaz:
https://doaj.org/article/5466d6d5ba47428695d8f90e4954f2c4
Autor:
Drahomíra Holmannová, Martina Koláčková, Kateřina Kondělková, Pavel Kuneš, Jan Krejsek, Ctirad Andrýs
Publikováno v:
Acta Medica, Vol 55, Iss 1, Pp 12-17 (2012)
CD200/CD200R are highly conserved type I paired membrane glycoproteins that belong to the Ig superfamily containing a two immunoglobulin‑like domain (V, C). CD200 is broadly distributed in a variety of cell types, whereas CD200R is primarily expres
Externí odkaz:
https://doaj.org/article/4d3071d89a9a415ea6ddfd96aa47496d
Publikováno v:
Acta Medica, Vol 53, Iss 3, Pp 125-129 (2010)
The recently recognized cytokine interleukin-33 and its receptor ST2 play a favorable role during atherogenesis by inducing a Th1→Th2 shift of the immune response. IL-33 also protects the failing human heart from harmful biomechanical forces which
Externí odkaz:
https://doaj.org/article/07fedbba628b47f48936de66b106a0c2
Autor:
Jan Krejsek, Martina Koláčková, Vladimír Lonský, Manuela Trojáčková Kudlová, Jiří Manďák, Pavel Kuneš, Karolína Jankovičová, Dana Vlášková, Ctirad Andrýs
Publikováno v:
Acta Medica, Vol 52, Iss 4, Pp 149-153 (2009)
Background: Cardiac surgery provokes a systemic inflammatory response in any patient. This complex body reaction involves also RANK/RANKL molecules which have been recently identified as principal regulators of bone metabolism. Aims: To follow the ch
Externí odkaz:
https://doaj.org/article/25800246dabd45cdaba429f4b0d82603
Publikováno v:
Acta Medica, Vol 52, Iss 4, Pp 135-139 (2009)
Practically all mammalian cells including human can switch, according to micro- or macroenvironmental conditions, from states of cellular quiescence to inflammatory activation and vice versa. Along with recent knowledge, cellular quiescence is not a
Externí odkaz:
https://doaj.org/article/983624f4d04d4631aa9d474e2afad45e
Autor:
Karolína Jankovičová, Manuela Trojáčková Kudlová, Martina Koláčková, Pavel Kuneš, Jiří Manďák, Vladimír Lonský, Dana Vlášková, Ctirad Andrýs, Jan Krejsek
Publikováno v:
Acta Medica, Vol 51, Iss 1, Pp 25-29 (2008)
Background: Cardiac surgery using cardiopulmonary bypass (CPB) is associated with some adverse postoperative complications caused by an altered immune response. An alternative approach to cardiac surgery, operating without the use of CPB (i.e. off-pu
Externí odkaz:
https://doaj.org/article/387a21938c574a748998385ffc5ed4e0
Autor:
Martina Koláčková, Manuela Trojáčková Kudlová, Vladimír Lonský, Jiří Manďák, Pavel Kuneš, Karolína Jankovičová, Dana Vlášková, Ctirad Andrýs, Jan Krejsek
Publikováno v:
Acta Medica, Vol 51, Iss 1, Pp 31-35 (2008)
Background: This study was aimed at following the changes in the expression of CD38 ADP-ribosyl cyclase ectoenzyme on peripheral blood immune cells of patients undergoing cardiac surgical operations. Patients and Methods: The expression of CD38 on ly
Externí odkaz:
https://doaj.org/article/1cb97cbe31cf47a2b92a1755b6e22756
Autor:
Manuela Kudlová, Martina Koláčková, Pavel Kuneš, Vladimír Lonský, Jiří Manďák, Ctirad Andrýs, Jan Krejsek
Publikováno v:
Acta Medica, Vol 50, Iss 3, Pp 187-193 (2007)
Background: Myeloid cells are extensively activated in patients undergoing cardiosurgical operations. It is supposed that this activation is more profound in patients operated with cardiopulmonary bypass (CPB) („on-pump“) in comparison with patie
Externí odkaz:
https://doaj.org/article/91c3e08f40b0413580f4ffcd1e4609f4
Autor:
Pavel Kuneš, Vladimír Lonský, Jiří Manďák, Miroslav Brtko, Martina Koláčková, Ctirad Andrýs, Manuela Kudlová, Jan Krejsek
Publikováno v:
Acta Medica, Vol 50, Iss 2, Pp 93-99 (2007)
Cardiac surgical operations are associated with the development of a systemic inflammatory response syndrome (SIRS). In most cases, the inflammatory response is apparent only in its subclinical form. In some cases, however, it can become clinically m
Externí odkaz:
https://doaj.org/article/0c12d6bf0e124fddbc0225e291a75e9a