Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Pavel Kramata"'
1
Why do psychiatric patients stop antipsychotic medication? A systematic review of reasons for nonadherence to medication in patients with serious mental illness
Autor: John P. Docherty, Pavel Kramata, Martha Sajatovic, Ainslie Hatch, Dawn I. Velligan
Publikováno v: Patient preference and adherence
Background Antipsychotic medication reduces the severity of serious mental illness (SMI) and improves patient outcomes only when medicines were taken as prescribed. Nonadherence to the treatment of SMI increases the risk of relapse and hospitalizatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e273f54fe6820485a5a1c9470a3b9d71
https://doi.org/10.2147/ppa.s124658
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2
Regulation of Hedgehog Signaling in Cancer by Natural and Dietary Compounds
Autor: Nanjoo Suh, Hong Jin Lee, Pavel Kramata, Cheng Bao
Publikováno v: Molecular nutritionfood research. 62(1)
The aberrant Hedgehog (Hh) signaling induced by mutations or overexpression of the signaling mediators has been implicated in cancer, associated with processes including inflammation, tumor cell growth, invasion, and metastasis, as well as cancer ste
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539a8121dcf7f9b148d541e6d787cabe
https://pubmed.ncbi.nlm.nih.gov/29164817
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4
Effect of administration of caffeine or green tea on the mutation profile in the p53 gene in early mutant p53-positive patches of epidermal cells induced by chronic UVB-irradiation of hairless SKH-1 mice
Autor: Meir Olcha, Julie L. Cohen, Pavel Kramata, Sandy Liu, Allan H. Conney, You-Rong Lou, Yao-Ping Lu
Publikováno v: Carcinogenesis. 26:1965-1974
Irradiation of SKH-1 mice with UVB light for 20 weeks resulted in a large number of patches of epidermal cells, which was visualized with an antibody that recognizes mutated p53 protein. Oral treatment of mice with caffeine (0.4 mg/ml) or green tea (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f94fd3f60e938d7086b5ca43c02746
https://doi.org/10.1093/carcin/bgi162
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5
Patches of Mutant p53-Immunoreactive Epidermal Cells Induced by Chronic UVB Irradiation Harbor the Same p53 Mutations as Squamous Cell Carcinomas in the Skin of Hairless SKH-1 Mice
Autor: Yao-Ping Lu, Sherry M. Kwon, Rayvita N. Singh, Allan H. Conney, You-Rong Lou, Pavel Kramata
Publikováno v: Cancer Research. 65:3577-3585
Treatment of SKH-1 hairless mice with UVB (30 mJ/cm2) twice a week for 20 weeks results in the formation of cellular patches, long before the appearance of tumors, that are visualized in epidermal sheets with an antibody (PAb240) recognizing mutated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90edd524ac46301e520addfa73c1d5fe
https://doi.org/10.1158/0008-5472.can-04-4537
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6
A Single Site-specific trans-Opened 7,8,9,10-Tetrahydrobenzo[a]pyrene 7,8-Diol 9,10-EpoxideN2-Deoxyguanosine Adduct Induces Mutations at Multiple Sites in DNA
Autor: Barbara Zajc, Pavel Kramata, Jane M. Sayer, Caroline S.-J. Wei, Donald M. Jerina
Publikováno v: Journal of Biological Chemistry. 278:14940-14948
Site-specific mutagenicity of trans-opened adducts at the exocyclic N(2)-amino group of guanine by the (+)-(7R,8S,9S,10R)- and (-)-(7S,8R,9R,10S)-enantiomers of a benzo[a]pyrene 7,8-diol 9,10-epoxide (7-hydroxyl and epoxide oxygen are trans, BPDE-2)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7498d6738b0bb4fbd7f148d8270b339b
https://doi.org/10.1074/jbc.m211557200
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7
Nonproteolyzed Form of DNA-Polymerase ε from T-Cell Spontaneous Lymphoma of Sprague-Dawley Inbred Rat: Isolation and Characterization
Autor: Antonín Holý, Pavel Kramata, Ivan Votruba, Otová B, Miroslav Otmar, Gabriel Birkus
Publikováno v: Collection of Czechoslovak Chemical Communications. 63:723-731
Using a simple isolation procedure and selective assay for the determination of enzyme activity the nonproteolyzed and proteolyzed form of DNA-polymerase ε (pol ε and pol ε*) from the lymphoma of Sprague-Dawley inbred rats were purified. Nonproteo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e3a94ba1f2c8ab05880adae9eb99b96
https://doi.org/10.1135/cccc19980723
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9
DNA-Polymerases α, δ and ε from T-Cell Spontaneous Lymphoblastic Leukemia of Sprague-Dawley Inbred Rat: Isolation and Characterization
Autor: Jaroslav Černý, Gabriel Birkus, Otová B, Antonín Holý, Pavel Kramata, Ivan Votruba
Publikováno v: Collection of Czechoslovak Chemical Communications. 60:1555-1572
Using a single isolation procedure and selective assays for the determination of enzyme activity, highly purified DNA-polymerases α, δ and ε were isolated from the lymphoma of Sprague-Dawley inbred rats. For pol α the subunit composition was 170,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44d3a1a786fc77ed4eb3a4287e76798b
https://doi.org/10.1135/cccc19951555
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10
ChemInform Abstract: Enzymes of Human Herpesviruses
Autor: Pavel Kramata, Ivan Votruba
Publikováno v: ChemInform. 23
The properties of human herpesvirus-encoded enzymes are reviewed and the importance of sequence analysis of viral genomes as well as the experiments on characteristics of enzymes isolated from infected cell cultures are emphasized. The following enzy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39d59833fc9491c9af247482e683aafc
https://doi.org/10.1002/chin.199252333
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