Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Pavel KOVALENKO"'
Autor:
Mohamed A. Kamal, John D. Davis, Pavel Kovalenko, Kamal Srinivasan, Eric L. Simpson, Takeshi Nakahara, Makoto Sugaya, Atsuyuki Igarashi, Marius Ardeleanu, Christine Xu, Kazuhiko Arima
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 10, Pp 2342-2354 (2022)
Abstract The pharmacokinetics (PKs) and exposure–efficacy of dupilumab have not been fully described for adults with atopic dermatitis (AD). Our objectives were to analyze the PKs and exposure–efficacy of dupilumab in adults with AD and compare t
Externí odkaz:
https://doaj.org/article/b9fa205e771d434aa40f75c1b135e648
Autor:
Pavel Kovalenko, Anne Paccaly, Anita Boyapati, Christine Xu, Gregory St John, Michael C. Nivens, John D. Davis, Ronda Rippley, A. Thomas DiCioccio
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 7, Pp 405-414 (2020)
Evidence suggests that effects of interleukin‐6 pathway inhibitors sarilumab, tocilizumab, and sirukumab on absolute neutrophil count (ANC) are due to margination of circulating neutrophils into rapidly mobilizable noncirculating pools. We develope
Externí odkaz:
https://doaj.org/article/67c9b10110704a98b5052e51a5d05f23
Publikováno v:
Proceedings on Engineering Sciences, Vol 1, Iss 1, Pp 365-369 (2019)
In this paper, a model for calculation of the temperature distribution in the metal tribopair bar - plane in the conditions of dry friction is developed. A model for solving of the problem of thermoelasticity for a metal bar under uniaxial tension-co
Externí odkaz:
https://doaj.org/article/ca04f14c7ca24c4492fb36793d479cad
Autor:
Pavel KOVALENKO, Svetlana PEREPELKINA
Publikováno v:
Proceedings on Engineering Sciences, Vol 1, Iss 1, Pp 330-334 (2019)
In this paper, the research of friction coefficient changes in the tribopairs carbon-fiber-reinforced silicon carbide (C/SiC) – steel 37Cr4 and C/SiC – steel C22 used in cars brake systems was carried out for the selection of suitable materials a
Externí odkaz:
https://doaj.org/article/500842c253af46b299bce585d74b449c
Autor:
Gavin Thurston, Nicholas Papadopoulos, Jessica R. Kirshner, Julian Andreev, Jeanette Fairhurst, Eric Smith, Irene Noguera-Troise, Pavel Kovalenko, Jing Shan, Carlos Hickey, Nithya Thambi, Sandra Coetzee, Guoying Chen, Frank Kuhnert
Supplementary Table S1: Dll4 Ab REGN421 binds human and monkey Dll4 with high affinity Supplementary Table S2: Combined blockade of Dll4 and VEGF signaling results in enhanced inhibition of A2780 ovarian tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8196565dfcf9d301cb85a669e8bdab
https://doi.org/10.1158/0008-5472.22405593.v1
https://doi.org/10.1158/0008-5472.22405593.v1
Autor:
Gavin Thurston, Nicholas Papadopoulos, Jessica R. Kirshner, Julian Andreev, Jeanette Fairhurst, Eric Smith, Irene Noguera-Troise, Pavel Kovalenko, Jing Shan, Carlos Hickey, Nithya Thambi, Sandra Coetzee, Guoying Chen, Frank Kuhnert
Legends for Supplementary Figures S1-S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43577273ca4f415803c778975e9363ce
https://doi.org/10.1158/0008-5472.22405605.v1
https://doi.org/10.1158/0008-5472.22405605.v1
Autor:
Gavin Thurston, Nicholas Papadopoulos, Jessica R. Kirshner, Julian Andreev, Jeanette Fairhurst, Eric Smith, Irene Noguera-Troise, Pavel Kovalenko, Jing Shan, Carlos Hickey, Nithya Thambi, Sandra Coetzee, Guoying Chen, Frank Kuhnert
Legends for Supplementary Tables S1 and S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3287fc796b7cc38293148da5f833f165
https://doi.org/10.1158/0008-5472.22405602
https://doi.org/10.1158/0008-5472.22405602
Autor:
Gavin Thurston, Nicholas Papadopoulos, Jessica R. Kirshner, Julian Andreev, Jeanette Fairhurst, Eric Smith, Irene Noguera-Troise, Pavel Kovalenko, Jing Shan, Carlos Hickey, Nithya Thambi, Sandra Coetzee, Guoying Chen, Frank Kuhnert
Supplementary Figure S1: Correlation of REGN421 serum concentrations and anti-HT1080 tumor activity Supplementary Figure S2: The potent anti-tumor activity of targeting Dll4 in ovarian xenograft models is dependent on blocking stromal Dll4 Supplement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2dc5e21bb66fbd1d5c2e06bddcedc1
https://doi.org/10.1158/0008-5472.22405596
https://doi.org/10.1158/0008-5472.22405596
Autor:
Pavel Kovalenko, Christine Xu, Brad Shumel, John D. Davis, Nidal Huniti, Ashish Bansal, Mohamed A. Kamal, A. Thomas DiCioccio
Publikováno v:
Clinical Pharmacology in Drug Development
Population pharmacokinetic (PK) base and covariate analyses were conducted using data from adolescents with moderate‐to‐severe atopic dermatitis (AD) and children ≥6 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20f5716d0c0cbbaafff62d6f690bc08
https://doi.org/10.1002/cpdd.986
https://doi.org/10.1002/cpdd.986
Autor:
Victor Musalimov, Jaroslav Hlava, Irina Rubinshtein, Ivan Ovchinnikov, David Krcmarik, Vu Trieu Minh, Reza Moezzi, Mart Tamre, Pavel Kovalenko
Publikováno v:
Journal Européen des Systèmes Automatisés. 53:589-600
Human muscles and the central nervous system (CNS) play the key role to control the human movements and activities. The human CNS determines each human motion following three steps: estimation of the movement trajectory; calculation of required energ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20f97c925f2d338e7ffd38f2fa085463
https://doi.org/10.18280/jesa.530501
https://doi.org/10.18280/jesa.530501