Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Pavel I, Kitov"'
Autor:
Duong T. Bui, Zhixiong Li, Pavel I. Kitov, Ling Han, Elena N. Kitova, Marlène Fortier, Camille Fuselier, Philippine Granger Joly de Boissel, David Chatenet, Nicolas Doucet, Stephen M. Tompkins, Yves St-Pierre, Lara K. Mahal, John S. Klassen
Publikováno v:
ACS Central Science. 8:963-974
Electrospray ionization mass spectrometry (ESI-MS) is a powerful label-free assay for detecting noncovalent biomolecular complexes
Autor:
Duong T Bui, John S. Klassen, Elena N. Kitova, Pavel I. Kitov, Kelley W. Moremen, Matthew S. Macauley, Zhixiong Li, Lara K. Mahal, Warren W. Wakarchuk
Publikováno v:
Anal Chem
Carbohydrate-active enzymes (CAZymes) play critical roles in diverse physiological and pathophysiological processes and are important for a wide range of biotechnology applications. Kinetic measurements offer insight into the activity and substrate s
Autor:
Digantkumar Chapla, Elena N. Kitova, Pavel I. Kitov, John S. Klassen, Emily Rodrigues, Zhixiong Li, Kelley W. Moremen, Fahima Mozenah, Matthew S. Macauley
Publikováno v:
Anal Chem
Carbohydrate-Active enZymes (CAZymes) are involved in the synthesis, degradation, and modification of carbohydrates. They play critical roles in diverse physiological and pathophysiological processes, have important industrial and biotechnological ap
Autor:
Glen D. Armstrong, George L. Mulvey, Thomas P. Griener, Ravin Narain, Zhicheng Deng, Marya Ahmed, Joanna M. Sadowska, Eugenia Paszkiewicz, Pavel I. Kitov, David R. Bundle
Publikováno v:
Toxins, Vol 3, Iss 9, Pp 1065-1088 (2011)
Inhibition of AB5-type bacterial toxins can be achieved by heterobifunctional ligands (BAITs) that mediate assembly of supramolecular complexes involving the toxin’s pentameric cell membrane-binding subunit and an endogenous protein, serum amyloid
Externí odkaz:
https://doaj.org/article/94a8a4f28d5f47108e25639e91613b18
Autor:
Ratmir Derda, Elena N. Kitova, Pavel I. Kitov, John S. Klassen, Daniel Ferrer Vinals, Ling Han
Publikováno v:
Glycobiology. 30:49-57
Glycan interactions with glycan-binding proteins (GBPs) play essential roles in a wide variety of cellular processes. Currently, the glycan specificities of GBPs are most often inferred from binding data generated using glycan arrays, wherein the GBP
Autor:
Carmanah D. Hunter, Christopher W. Cairo, Elena N. Kitova, Jaesoo Jung, Pavel I. Kitov, Matthew S. Macauley, John S. Klassen, Zhixiong Li, Ling Han, Emily Rodrigues
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-7 (2019)
Communications Biology
Communications Biology
Glycan binding by glycan-binding proteins and processing by carbohydrate-active enzymes is implicated in physiological and pathophysiological processes. Comprehensive mapping of glycan interactions is essential to understanding of glycan-mediated bio
Publikováno v:
Analytical chemistry. 92(5)
Interactions between glycosphingolipids (GSLs) on the surfaces of cells and glycan-binding proteins (GBPs) mediate a wide variety of essential and pathological processes. Despite the biological importance of these interactions, the GSL ligands of mos
Autor:
Pavel I. Kitov, Joanna M. Sadowska, Qifang Wang, David R. Bundle, Chang-Chun Ling, Ping Zhang, Eugenia Paszkiewicz
Publikováno v:
Chemical Communications. 53:10528-10531
Using amphiphilic cyclodextrin as a scaffold, the first class of PK-glycoconjugates capable of high avidity binding to both Stx1 and Stx2 toxins in solid-phase assay formats is reported. The generated glycomicroarray effectively mimics the plasma mem
Autor:
John J. Dwyer, S. Kalhor-Monfared, J. T. Patterson, Pavel I. Kitov, Mohammad R. Jafari, Ratmir Derda, J. M. Nuss
Publikováno v:
Chemical Science
In this manuscript, we describe modification of Cys-residues in peptides and proteins in aqueous solvents via aromatic nucleophilic substitution (SNAr) with perfluoroarenes (fAr).
In this manuscript, we describe modification of Cys-residues in p
In this manuscript, we describe modification of Cys-residues in p
Autor:
Ping, Zhang, Eugenia, Paszkiewicz, Qifang, Wang, Joanna M, Sadowska, Pavel I, Kitov, David R, Bundle, Chang-Chun, Ling
Publikováno v:
Chemical communications (Cambridge, England). 53(76)
Using amphiphilic cyclodextrin as a scaffold, the first class of P