Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Pavel Damborsky"'
1
Full-length antibodies versus single-chain antibody fragments for a selective impedimetric lectin-based glycoprofiling of prostate specific antigen
Autor: Julia Zapatero-Rodríguez, Pavel Damborsky, Jan Tkac, Stefan Belicky, Richard O'Kennedy
Publikováno v: Electrochimica Acta. 246:399-405
The main aim of the research was to design a functional impedimetric biosensor able to glycoprofile prostate specific antigen (PSA), a biomarker for prostate cancer (PCa), with high specificity using lectins as glycan recognising proteins. Traditiona
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d06dde953a54a6ce4b17024233896b
https://doi.org/10.1016/j.electacta.2017.06.065
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2
Optimization of the Small Glycan Presentation for Binding a Tumor-Associated Antibody: Application to the Construction of an Ultrasensitive Glycan Biosensor
Autor: Jan Tkac, Anna Blsakova, Ola Blixt, Pavel Damborsky, Andras Hushegyi, Bo Jansson, Filip Kveton
Publikováno v: Langmuir. 33:2709-2716
The main aim of the study was to optimize the interfacial presentation of a small antigen - a Tn antigen (N-acetylgalactosamine) - for binding to its analyte anti-Tn antibody. Three different methods for the interfacial display of a small glycan are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad9d605481cd4b7c136db0863f21527
https://doi.org/10.1021/acs.langmuir.6b04021
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3
DNA aptamer-based sandwich microfluidic assays for dual quantification and multi-glycan profiling of cancer biomarkers
Autor: Narayanan Madaboosi, Jaroslav Katrlík, V. Chu, João Pedro Conde, Ruben R. G. Soares, Pavel Damborsky, Pedro Estrela, Pawan Jolly
Publikováno v: Jolly, P, Damborsky, P, Madaboosi, N, Soares, R R G, Chu, V, Conde, J P, Katrlik, J & Estrela, P 2016, ' DNA aptamer-based sandwich microfluidic assays for dual quantification and multi-glycan profiling of cancer biomarkers ', Biosensors and Bioelectronics, vol. 79, pp. 313-319 . https://doi.org/10.1016/j.bios.2015.12.058
Two novel sandwich-based immunoassays for prostate cancer (PCa) diagnosis are reported, in which the primary antibody for capture is replaced by a DNA aptamer. The assays, which can be performed in parallel, were developed in a microfluidic device an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af06e1942a8d2fbde1ab9f2e9000dcb9
https://doi.org/10.1016/j.bios.2015.12.058
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4
Akademický článek
Universal protocol for the wafer-scale manufacturing of 2D carbon-based transducer layers for versatile biosensor applications
Autor: Xiaoling Lu, Walid-Madhat Munief, Pavel Damborský, Alice Kasjanow, Jaroslav Katrlík, Vivek Pachauri, Sven Ingebrandt
Publikováno v: MethodsX, Vol 11, Iss , Pp 102402- (2023)
In this manuscript, we present a comprehensive fabrication protocol for high-performance graphene oxide (GO) sensor concepts. It is suitable for a variety of biosensing applications and contains the essential process steps, starting with vapor phase
Externí odkaz: https://doaj.org/article/d466bc7d3bd64dc98918fe0837d8ba5f
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5
Structure and Morphology of Microbial Degraded Poly(ε-caprolactone)/Graphite Oxide Composite
Autor: Sona Hermanova, Radka Balkova, Jirina Omelkova, Lukas Richtera, Stanislava Voberkova, Josef Jancar, Pavel Damborsky
Publikováno v: Journal of Polymers and the Environment. 22:190-199
Biodegradation of poly(e-caprolactone) composite with graphite oxide (GO) by the action of Bacillus subtilis (BS) was studied in this work. Nanocomposite produced in a form of thin film was exposed to nutrient cultivation medium with BS as well as to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6ce3947940b2ce59df5d2385e736cf5
https://doi.org/10.1007/s10924-013-0630-y
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6
An ultrasensitive impedimetric glycan biosensor with controlled glycan density for detection of lectins and influenza hemagglutinins
Autor: Pavel Damborsky, Tomas Bertok, Andras Hushegyi, Jaroslav Katrlík, Jan Tkac
Publikováno v: Chemical communications (Cambridge, England). 51(35)
Ultrasensitive impedimetric analysis of lectins and viral agglutinins was achieved by a glycan biosensor built on a mixed SAM (left) with controlled glycan density (right).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80186d65a77dad157fb775cbbfd97718
https://pubmed.ncbi.nlm.nih.gov/25828081
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8
Akademický článek
Electrical SPR biosensor with thermal annealed graphene oxide: Concept of highly sensitive biomolecule detection
Autor: Xiaoling Lu, Pavel Damborský, Walid-Madhat Munief, Jessica Ka-Yan Law, Xianping Chen, Jaroslav Katrlík, Vivek Pachauri, Sven Ingebrandt
Publikováno v: Biosensors and Bioelectronics: X, Vol 11, Iss , Pp 100152- (2022)
(Reduced) graphene oxides as promising 2D materials have been explored extensively to improve the performance characteristics of SPR sensors. Herein, we demonstrate the tuning optical properties of SPR biochips by the combination of two strategies: (
Externí odkaz: https://doaj.org/article/d41d6c33089e4005b02d59355111c34d
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