Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Pavel Chrobak"'
Autor:
John Stagg, Anne-Marie Mes-Masson, Rejean Lapointe, Pamela Thebault, David Allard, Isabelle Cousineau, Yacine Bareche, Sandra Pommey, Mayra Carneiro, Laurence Buisseret, Pavel Chrobak, Laudine Communal, Simon C Robson, Diane Provencher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Hydrolysis of extracellular ATP to adenosine (eADO) is an important immune checkpoint in cancer immunology. We here investigated the impact of the eADO pathway in high-grade serous ovarian cancer (HGSC) using multiparametric platforms.Meth
Externí odkaz:
https://doaj.org/article/79a64e0d29404bbdb5f83e93f3d2960a
Autor:
Bertrand Allard, Isabelle Cousineau, David Allard, Laurence Buisseret, Sandra Pommey, Pavel Chrobak, John Stagg
Publikováno v:
OncoImmunology, Vol 8, Iss 8 (2019)
The formation of new lymphatic vessels, or lymphangiogenesis, is a critical step of the tissue repair program. In pathological conditions involving chronic inflammation or tumorigenesis, this process is often dysregulated and can contribute to diseas
Externí odkaz:
https://doaj.org/article/4c6e80ae469f464d96f594cbcfcfdc21
Autor:
Pierre-Olivier Gaudreau, Sylvie Clairefond, Caleb A. Class, Pierre-Luc Boulay, Pavel Chrobak, Bertrand Allard, Feryel Azzi, Sandra Pommey, Kim-Anh Do, Fred Saad, Dominique Trudel, Marian Young, John Stagg
Publikováno v:
OncoImmunology, Vol 8, Iss 5 (2019)
Background: WNT1-Inducible Signaling Pathway Protein 1 (WISP1) is implicated in prostate cancer growth and metastasis and the regulation of inflammation in diverse benign diseases. The objectives of this study were to assess the prognostic value of W
Externí odkaz:
https://doaj.org/article/a0c5e75d7aaa425689de853adf2bcaf5
Autor:
John Stagg, Benjamin Haibe-Kains, Simon Turcotte, Simon C. Robson, Neha Rohatgi, Christopher B. Eeles, Heewon Seo, Andrew C. Lake, Ricard Masia, Secil Koseoglu, Geneviève Soucy, Yannic McNicoll, Nouredin Messaoudi, Sandra Pommey, Bertrand Allard, Pavel Chrobak, David Allard, Yacine Bareche, Isabelle Cousineau, Célia Jacoberger-Foissac
supplementary Table S1 to S3; Supplementary Figure S1 to S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5557b4fb8e198ff63d33ef665e3fb66b
https://doi.org/10.1158/2326-6066.22546016
https://doi.org/10.1158/2326-6066.22546016
Autor:
John Stagg, Benjamin Haibe-Kains, Simon Turcotte, Simon C. Robson, Neha Rohatgi, Christopher B. Eeles, Heewon Seo, Andrew C. Lake, Ricard Masia, Secil Koseoglu, Geneviève Soucy, Yannic McNicoll, Nouredin Messaoudi, Sandra Pommey, Bertrand Allard, Pavel Chrobak, David Allard, Yacine Bareche, Isabelle Cousineau, Célia Jacoberger-Foissac
The ectonucleotidases CD39 and CD73 catalyze extracellular ATP to immunosuppressive adenosine, and as such, represent potential cancer targets. We investigated biological impacts of CD39 and CD73 in pancreatic ductal adenocarcinoma (PDAC) by studying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b4572cefcaedc2bd1e671c7a1e94c4
https://doi.org/10.1158/2326-6066.c.6551072
https://doi.org/10.1158/2326-6066.c.6551072
Autor:
John Stagg, Pavel Chrobak, Sandra Pommey, Martin Turcotte, Laurence Buisseret, David Allard, Bertrand Allard, Roxanne Charlebois
Innate and adaptive immune cells play an important role in the therapeutic activity of anti-ErbB2 mAbs, such as trastuzumab. In the clinic, breast tumors poorly infiltrated with immune cells are more resistant to trastuzumab, and patients have a wors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5d986db6450b8de68d024ea399d934
https://doi.org/10.1158/0008-5472.c.6509208
https://doi.org/10.1158/0008-5472.c.6509208
Autor:
John Stagg, Pavel Chrobak, Sandra Pommey, Martin Turcotte, Laurence Buisseret, David Allard, Bertrand Allard, Roxanne Charlebois
Data of memory response, single agent activity, tumor sizes at time of flow cytometry analysis and antibody-mediated cellular cytotoxicity of trastuzumab-treated BT-474 cells is shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c4542dc3e07f7b10a73c543dd0a2e5
https://doi.org/10.1158/0008-5472.22415235.v1
https://doi.org/10.1158/0008-5472.22415235.v1
Autor:
Chunyan Hu, Elena Priceputu, Marc Cool, Pavel Chrobak, Nathalie Bouchard, Clara Forestier, Clifford A. Lowell, Serge Bénichou, Zaher Hanna, Virginie Royal, Paul Jolicoeur
Publikováno v:
The American Journal of Pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7e3c9fd8063a1bb947c968a61f9a2f0
https://doi.org/10.1016/j.ajpath.2023.02.006
https://doi.org/10.1016/j.ajpath.2023.02.006
Autor:
Célia Jacoberger-Foissac, Isabelle Cousineau, Yacine Bareche, David Allard, Pavel Chrobak, Bertrand Allard, Sandra Pommey, Nouredin Messaoudi, Yannic McNicoll, Geneviève Soucy, Secil Koseoglu, Ricard Masia, Andrew C. Lake, Heewon Seo, Christopher B. Eeles, Neha Rohatgi, Simon C. Robson, Simon Turcotte, Benjamin Haibe-Kains, John Stagg
Publikováno v:
Cancer Immunol Res
The ectonucleotidases CD39 and CD73 catalyze extracellular ATP to immunosuppressive adenosine, and as such, represent potential cancer targets. We investigated biological impacts of CD39 and CD73 in pancreatic ductal adenocarcinoma (PDAC) by studying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0e74f195e222380e757c09392eb7c1
https://europepmc.org/articles/PMC9812927/
https://europepmc.org/articles/PMC9812927/
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191973 (2018)
Many individuals at risk of streptococcal infection respond poorly to the pneumococcal polysaccharide vaccine Pneumovax 23. Identification of actionable pathways able to enhance Pneumovax responsiveness is highly relevant. We investigated the contrib
Externí odkaz:
https://doaj.org/article/f308180108654aab869fa5f372243a00