Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Pavel A. Makhnovskii"'
Autor:
Pavel A. Makhnovskii, Oleg A. Gusev, Roman O. Bokov, Guzel R. Gazizova, Tatiana F. Vepkhvadze, Evgeny A. Lysenko, Olga L. Vinogradova, Fedor A. Kolpakov, Daniil V. Popov
Publikováno v:
Human Genomics, Vol 16, Iss 1, Pp 1-13 (2022)
Abstract Background More than half of human protein-coding genes have an alternative transcription start site (TSS). We aimed to investigate the contribution of alternative TSSs to the acute-stress-induced transcriptome response in human tissue (skel
Externí odkaz:
https://doaj.org/article/90be882482be4e3da645e03593845d99
Autor:
Daniil V. Popov, Evgeny A. Lysenko, Pavel A. Makhnovskii, Nadia S. Kurochkina, Olga L. Vinogradova
Publikováno v:
Physiological Reports, Vol 5, Iss 23, Pp n/a-n/a (2017)
Abstract Promoter‐specific expression of the PPARGC1A gene in untrained and trained human skeletal muscle was investigated. Ten untrained males performed a one‐legged knee extension exercise (for 60 min) with the same relative intensity both befo
Externí odkaz:
https://doaj.org/article/5b42fde1dc064369944920ebb3751deb
Autor:
Daniil V. Popov, Pavel A. Makhnovskii, Viktor G. Zgoda, Guzel R. Gazizova, Tatiana F. Vepkhvadze, Egor M. Lednev, Evgeniia S. Motanova, Evgeny A. Lysenko, Oleg I. Orlov, Elena S. Tomilovskaya
Publikováno v:
Journal of Applied Physiology. 134:1256-1264
Three-day dry immersion (a model of physical unloading) substantially changes the transcriptomic profile in the human soleus muscle, a muscle with predominantly slow-twitch fibers and strong postural function; despite this, we found no effect on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::678ffef9570ccf13c96fdc6cf6690621
https://doi.org/10.1152/japplphysiol.00048.2023
https://doi.org/10.1152/japplphysiol.00048.2023
Publikováno v:
Biochemistry (Moscow). 87:1021-1034
Skeletal muscles mainly contribute to the emergence of insulin resistance, impaired glucose tolerance and the development of type 2 diabetes. Molecular mechanisms that regulate glucose uptake are diverse, including the insulin-dependent as most impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b214f7d26e90fa9579b2720e47fcc7d4
https://doi.org/10.1134/s0006297922090139
https://doi.org/10.1134/s0006297922090139
Autor:
L. N. Nefedova, I. V. Kuzmin, P. A. Milyaeva, Pavel A. Makhnovskii, I. V. Kukushkina, A. I. Kim, A. R. Lavrenov
Publikováno v:
Russian Journal of Genetics. 56:562-571
To study the causes of impaired control of the activity of mobile genetic elements in the strains with the flamenco phenotype SS (w, flamenco mutant) and MS (w, flamenco mutant, active copy of gypsy), sequencing of these transcriptomes was performed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0adb5c8dc3b450ec5541b3620dfe71ff
https://doi.org/10.1134/s1022795420050087
https://doi.org/10.1134/s1022795420050087
Autor:
A. I. Kim, Pavel A. Makhnovskii, I. V. Kuzmin, N. I. Romanova, I. V. Kukushkina, A. R. Lavrenov, L. N. Nefedova, E A Balakireva
Publikováno v:
Молекулярная биология. 54:412-425
The flamenco locus is one of the main components of the piRNA pathway of regulation of mobile genetic elements (MGEs) in Drosophila melanogaster. Mutations at this locus lead to an increase in the transposition activity of MGEs and, as a result, to g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fb624fe2048a348b2e3d5f943313f58
https://doi.org/10.31857/s002689842003009x
https://doi.org/10.31857/s002689842003009x
Autor:
Daniil V. Popov, G. R. Gazizova, Olga Vinogradova, Oleg Gusev, Pavel A. Makhnovskii, E. A. Lysenko, Elena Shagimardanova
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 316:E605-E614
Reduction in daily activity leads to dramatic metabolic disorders, while regular aerobic exercise training is effective for preventing this problem. The purpose of this study was to identify genes that are directly related to contractile activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541cffe2bec80563323f763b72aa994c
https://doi.org/10.1152/ajpendo.00449.2018
https://doi.org/10.1152/ajpendo.00449.2018
Autor:
O. V. Tyapkina, Oleg Gusev, S. S. Pintus, Ilya R. Akberdin, Fedor A. Kolpakov, Elena Shagimardanova, Ivan S. Yevshin, G. R. Gazizova, Islam Nigmetzyanov, Daniil V. Popov, Pavel A. Makhnovskii, Ruslan Devyatiyarov, L. F. Nurullin
Publikováno v:
Biology
Biology, Vol 10, Iss 557, p 557 (2021)
Volume 10
Issue 6
Biology, Vol 10, Iss 557, p 557 (2021)
Volume 10
Issue 6
Simple Summary The genetic process underlying the control of skeletal muscle homeostasis is a key factor in methods that develop technologies to prevent age and immobility-driven atrophy. In the current paper, using advanced methods for the whole-gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e99bc99232f81e2a7e56b65eec83a5
https://pubmed.ncbi.nlm.nih.gov/34203013
https://pubmed.ncbi.nlm.nih.gov/34203013
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 1208, p 1208 (2021)
Volume 22
Issue 3
International Journal of Molecular Sciences, Vol 22, Iss 1208, p 1208 (2021)
Volume 22
Issue 3
Inactivity is associated with the development of numerous disorders. Regular aerobic exercise is broadly used as a key intervention to prevent and treat these pathological conditions. In our meta-analysis we aimed to identify and compare (i) the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2ae33b27bb559c088ee17820f671c6
http://europepmc.org/articles/PMC7866200
http://europepmc.org/articles/PMC7866200
Autor:
Elena Shagimardanova, G. R. Gazizova, Victor G. Zgoda, Daniil V. Popov, Olga Vinogradova, Pavel A. Makhnovskii, Fedor A. Kolpakov, Oleg Gusev, E. A. Lysenko, Roman O. Bokov
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Regular low intensity aerobic exercise (aerobic training) provides effective protection against various metabolic disorders. Here, the roles played by transient transcriptome responses to acute exercise and by changes in baseline gene expression duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d78846d2ee5cd429cb2f3e39690db52
http://europepmc.org/articles/PMC7044165
http://europepmc.org/articles/PMC7044165