Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Pavel A. Levkin"'
Autor:
Joaquín E. Urrutia Gómez, Razan El Khaled El Faraj, Moritz Braun, Pavel A. Levkin, Anna A. Popova
Publikováno v:
SLAS Technology, Vol 29, Iss 1, Pp 100118- (2024)
The Droplet Microarray (DMA) has emerged as a tool for high-throughput biological and chemical applications by enabling miniaturization and parallelization of experimental processes. Due to its ability to hold hundreds of nanoliter droplets, the DMA
Externí odkaz:
https://doaj.org/article/acec8b5f7da94049ae24c4f84e91840c
Autor:
Yanchen Wu, Joaquin E. Urrutia Gomez, Hongmin Zhang, Fei Wang, Pavel A. Levkin, Anna A. Popova, Britta Nestler
Publikováno v:
Droplet, Vol 3, Iss 1, Pp n/a-n/a (2024)
Abstract Precise control of the evaporation of multiple droplets on patterned surfaces is crucial in many technological applications, such as anti‐icing, coating, and high‐throughput assays. Yet, the complex evaporation process of multiple drople
Externí odkaz:
https://doaj.org/article/4d35ce935b254c8c8435562579f31b06
Autor:
Marcel P. Schilling, Razan El Khaled El Faraj, Joaquín Eduardo Urrutia Gómez, Steffen J. Sonnentag, Fei Wang, Britta Nestler, Véronique Orian-Rousseau, Anna A. Popova, Pavel A. Levkin, Markus Reischl
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Cancer is a devastating disease and the second leading cause of death worldwide. However, the development of resistance to current therapies is making cancer treatment more difficult. Combining the multi-omics data of individual tumors with
Externí odkaz:
https://doaj.org/article/79d6fc0384074a8a821dd2ae350134cb
Autor:
Qingyu Xu, Alexander Streuer, Johann-Christoph Jann, Eva Altrock, Nanni Schmitt, Johanna Flach, Carla Sens-Albert, Felicitas Rapp, Julia Wolf, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Mariia Kuzina, Ahmed Jawhar, Ali Darwich, Cleo-Aron Weis, Alexander Marx, Patrick Wuchter, Victor Costina, Evelyn Jäger, Elena Sperk, Michael Neumaier, Alice Fabarius, Georgia Metzgeroth, Florian Nolte, Laurenz Steiner, Pavel A. Levkin, Mohamad Jawhar, Wolf-Karsten Hofmann, Vladimir Riabov, Daniel Nowak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Hypomethylating agents, such as 5-Azacytidine (5-AZA), are standard of care for patients with myelodysplastic and myeloid malignancies, however response rates are limited and risk of relapses high. Here the authors show that inhibition of lysyl oxida
Externí odkaz:
https://doaj.org/article/91b523f59ac547d99572fb13b46e1d2f
Autor:
Michelle J. Iwohn, Maximilian Seifermann, Patrick Reiser, Julius Höpfner, Razan El Khaled El Faraj, Stefan Heißler, Anna A. Popova, Pavel A. Levkin
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 21, Pp n/a-n/a (2023)
Abstract Immobilization of oligonucleotides on solid surfaces is an important step in many experimental workflows in biology, such as gene expression analysis, genotyping, and drug discoveries. Capturing oligonucleotides in a highly efficient miniatu
Externí odkaz:
https://doaj.org/article/86fd5797d1954aeda5421c27ceb8fafd
Autor:
Dmitrii D. Kartsev, Artur Y. Prilepskii, Ilia M. Lukyanov, Eduard G. Sharapenkov, Anastasiia V. Klaving, Aleksandr Goltaev, Alexey Mozharov, Liliia Dvoretckaia, Ivan Mukhin, Pavel A. Levkin
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 16, Pp n/a-n/a (2023)
Abstract Surfaces with special wettability properties, such as omniphobicity or omniphilicity, are essential for functional devices that use both aqueous and organic media. Micropatterning of omniphobic and omniphilic properties can provide a wide ra
Externí odkaz:
https://doaj.org/article/a8e07d3b7fad4d4786020f92c12c9831
Autor:
Anna A. Popova, Markus Reischl, Daniel Kazenmaier, Haijun Cui, Timo Amberger, Pavel A. Levkin
Publikováno v:
SLAS Technology, Vol 27, Iss 1, Pp 44-53 (2022)
Simple and rapid imaging and analysis of 2D and 3D cell culture compatible with miniaturized arrays of nanoliter droplets are essential for high-throughput screening and personalized medicine applications. In this study, we have developed a simple on
Externí odkaz:
https://doaj.org/article/6bd1d3dcffa44de8b690329655424b3c
Autor:
Haijun Cui, Tina Tronser, Xianxian Wang, Janine Wesslowski, Gary Davidson, Anna A. Popova, Pavel A. Levkin
Publikováno v:
Droplet, Vol 2, Iss 1, Pp n/a-n/a (2023)
Abstract Most of the biological processes, including cell signaling, cancer invasion, embryogenesis, or neural development, are dependent on and guided by the complex architecture and composition of cellular microenvironments. Mimicking such microenv
Externí odkaz:
https://doaj.org/article/744a5e59683e4135999b6aead797e608
Autor:
Zheqin Dong, Haijun Cui, Haodong Zhang, Fei Wang, Xiang Zhan, Frederik Mayer, Britta Nestler, Martin Wegener, Pavel A. Levkin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
3D printing offers flexibility in fabrication of polymer objects but fabrication of large polymer structures with micrometer-sized geometrical features are challenging. Here, the authors introduce a method combining advantages of 3D printing and poly
Externí odkaz:
https://doaj.org/article/7b4ed0b79af749ab99f1f277fd511461
Autor:
Marcel P. Schilling, Svenja Schmelzer, Joaquin Eduardo Urrutia Gomez, Anna A. Popova, Pavel A. Levkin, Markus Reischl
Publikováno v:
IEEE Access, Vol 9, Pp 166027-166038 (2021)
Grid structures are common in high-throughput assays to parallelize experiments in biochemical or biological experiments. Manual analysis of grid images is laborious, time-consuming, expensive, and critical in terms of reproducibility. However, it is
Externí odkaz:
https://doaj.org/article/eb245693f65547e5b89c85d4920f26c2