Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Pavel A. Baranov"'
Autor:
Patrick B. F. O’Connor, Jennifer Mahony, Eoghan Casey, Pavel V. Baranov, Douwe van Sinderen, Martina M. Yordanova
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTBacteria have evolved diverse defense mechanisms to counter bacteriophage attacks. Genetic programs activated upon infection characterize phage–host molecular interactions and ultimately determine the outcome of the infection. In this study
Externí odkaz:
https://doaj.org/article/686b9e90ff334a5f9f68107dec1dc818
Autor:
Mehdi Amiri, Stephen J. Kiniry, Anthony P. Possemato, Niaz Mahmood, Tayebeh Basiri, Catherine R. Dufour, Negar Tabatabaei, Qiyun Deng, Michael A. Bellucci, Keerthana Harwalkar, Matthew P. Stokes, Vincent Giguère, Randal J. Kaufman, Yojiro Yamanaka, Pavel V. Baranov, Soroush Tahmasebi, Nahum Sonenberg
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113615- (2024)
Summary: The integrated stress response (ISR) is critical for cell survival under stress. In response to diverse environmental cues, eIF2α becomes phosphorylated, engendering a dramatic change in mRNA translation. The activation of ISR plays a pivot
Externí odkaz:
https://doaj.org/article/18af2fe7b35548578596dd8ed96f88ce
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract The synthesis of most proteins begins at AUG codons, yet a small number of non-AUG initiated proteoforms are also known. Here we analyse a large number of publicly available Ribo-seq datasets to identify novel, previously uncharacterised non
Externí odkaz:
https://doaj.org/article/14d6f587a3ea4037a0db7d86278ff798
Autor:
Samer Girgis, Zaikun Xu, Spyros Oikonomopoulos, Alla D. Fedorova, Egor P. Tchesnokov, Calvin J. Gordon, T. Martin Schmeing, Matthias Götte, Nahum Sonenberg, Pavel V. Baranov, Jiannis Ragoussis, Tom C. Hobman, Jerry Pelletier
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Genomes from defective interfering (DI) particles following serial passaging of SARS-CoV-2 reveal a fusion protein that attenuates viral replication. Synthetic, recombinant DI genomes are designed to interfere with SARS-CoV-2 replication.
Externí odkaz:
https://doaj.org/article/5e493b54c37c47c3a8ea41d5c87f53e3
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5270963e2d764e298a6b93db10594636
Autor:
Oro Uchenunu, Alexander V. Zhdanov, Phillipe Hutton, Predrag Jovanovic, Ye Wang, Dmitry E. Andreev, Laura Hulea, David J. Papadopoli, Daina Avizonis, Pavel V. Baranov, Michael N. Pollak, Dmitri B. Papkovsky, Ivan Topisirovic
Publikováno v:
FEBS Open Bio, Vol 12, Iss 5, Pp 959-982 (2022)
Mutations in genes encoding cytochrome c oxidase (mitochondrial complex IV) subunits and assembly factors [e.g., synthesis of cytochrome c oxidase 2 (SCO2)] are linked to severe metabolic syndromes. Notwithstanding that SCO2 is under transcriptional
Externí odkaz:
https://doaj.org/article/f8fde63c9e464bee9765b343a923087e
Autor:
Dmitry E. Andreev, Gary Loughran, Alla D. Fedorova, Maria S. Mikhaylova, Ivan N. Shatsky, Pavel V. Baranov
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Recent proteogenomic studies revealed extensive translation outside of annotated protein coding regions, such as non-coding RNAs and untranslated regions of mRNAs. This non-canonical translation is largely due to start codon plurality within
Externí odkaz:
https://doaj.org/article/29b0c5b7edd04b93a58129c5788f35cd
Autor:
Martina M Yordanova, Pavel V Baranov
Publikováno v:
eLife, Vol 11 (2022)
The efficiency with which ribosomes shift reading frames when decoding viral RNA may change over the course of an infection.
Externí odkaz:
https://doaj.org/article/638e0cdb45be4e22bc45081a5e7a87c4
Publikováno v:
Wellcome Open Research, Vol 5 (2022)
Abstract Background: Previously we reported the discovery of stop codon readthrough in AMD1 mRNA followed by ribosome stalling at the end of a conserved Open Reading Frame (ORF) that we termed AMD1. To explain the severe suppression of reporters fuse
Externí odkaz:
https://doaj.org/article/26be2f3e6da746988e14f013438efe8c
Publikováno v:
Materials Research Express, Vol 10, Iss 11, p 116201 (2023)
Silicon vacancies in silicon carbide (SiC) have been proposed as interesting candidates for quantum technology applications such as quantum sensing and quantum repeaters. SiC exists in many polytypes with different plane stacking sequences, and in ea
Externí odkaz:
https://doaj.org/article/1ccff658c15a446eb07a9f4216a2bec7