Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Pavel A Brodskiy"'
Autor:
Ali Nematbakhsh, Wenzhao Sun, Pavel A Brodskiy, Aboutaleb Amiri, Cody Narciso, Zhiliang Xu, Jeremiah J Zartman, Mark Alber
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 5, p e1005533 (2017)
Mitotic rounding during cell division is critical for preventing daughter cells from inheriting an abnormal number of chromosomes, a condition that occurs frequently in cancer cells. Cells must significantly expand their apical area and transition fr
Externí odkaz:
https://doaj.org/article/7a4c4dd1e791492c969ba4a8ae4a52dc
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 12, p e1004679 (2015)
Embryogenesis is an extraordinarily robust process, exhibiting the ability to control tissue size and repair patterning defects in the face of environmental and genetic perturbations. The size and shape of a developing tissue is a function of the num
Externí odkaz:
https://doaj.org/article/01ae5eef01db4482a9e0ddf43154a441
Autor:
Staci L Solin, Ying Wang, Joshua Mauldin, Laura E Schultz, Deborah E Lincow, Pavel A Brodskiy, Crystal A Jones, Judith Syrkin-Nikolau, Jasmine M Linn, Jeffrey J Essner, Jesse M Hostetter, Elizabeth M Whitley, J Douglas Cameron, Hui-Hsien Chou, Andrew J Severin, Donald S Sakaguchi, Maura McGrail
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114888 (2014)
In this study we describe the molecular and cellular characterization of a zebrafish mutant that develops tumors in the optic pathway. Heterozygous Tg(flk1:RFP)is18 transgenic adults develop tumors of the retina, optic nerve and optic tract. Molecula
Externí odkaz:
https://doaj.org/article/717a136c648241dfbc1ea4db0391295c
G protein-coupled Receptor Contributions to Wing Growth and Morphogenesis in Drosophila melanogaster
Autor:
Francisco J. Huizar, Nilay Kumar, Maria Unger, Vijay Velagala, Qinfeng Wu, Pavel A. Brodskiy, Jeremiah J. Zartman
The development of multicellular organisms relies on a symphony of spatiotemporally coordinated signals that regulate gene expression. G protein-coupled receptors (GPCRs) are the largest group of transmembrane receptors that play a pivotal role in tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34881df8ba841e0ceb074c657bde4af6
https://doi.org/10.1101/2022.09.09.506847
https://doi.org/10.1101/2022.09.09.506847
Autor:
Nilay Kumar, Francisco J. Huizar, Keity J. Farfán-Pira, Pavel A. Brodskiy, Dharsan K. Soundarrajan, Marcos Nahmad, Jeremiah J. Zartman
Publikováno v:
Frontiers in Genetics. 13
Phenomics requires quantification of large volumes of image data, necessitating high throughput image processing approaches. Existing image processing pipelines for Drosophila wings, a powerful genetic model for studying the underlying genetics for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d6a1b4ac96ee342441c140df7629669
https://doi.org/10.3389/fgene.2022.869719
https://doi.org/10.3389/fgene.2022.869719
Autor:
Cody Narciso, Pavel A. Brodskiy, Jianxu Chen, Dharsan Soundarrajan, Megan Levis, Qinfeng Wu, Peixian Liang, Jeremiah J. Zartman, Ninfamaria Arredondo-Walsh, Danny Z. Chen, Francisco J. Huizar
Publikováno v:
Biophysical Journal. 116:725-740
The robust specification of organ development depends on coordinated cell-cell communication. This process requires signal integration among multiple pathways, relying on second messengers such as calcium ions. Calcium signaling encodes a significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b27b79df60396d6e670345702a66e2
https://doi.org/10.1016/j.bpj.2019.01.007
https://doi.org/10.1016/j.bpj.2019.01.007
Autor:
Francisco J. Huizar, Pavel A. Brodskiy, Maria F. Unger, Keity J. Farfan-Pira, Trent Robinett, Marcos Nahmad, Dharsan J Soundarrajan, Nilay Kumar, Jeremiah J. Zartman
SummaryPhenomics requires quantification of large volumes of image data, necessitating high throughput image processing approaches. Existing image processing pipelines forDrosophilawings, a powerful model for studying morphogenesis, are limited in sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::045fdd6c25f0dc027aa1a0b7827e3625
https://doi.org/10.1101/2020.12.16.422888
https://doi.org/10.1101/2020.12.16.422888
Autor:
Pavel A. Brodskiy, Jeremiah J. Zartman
Publikováno v:
Physical biology. 15(5)
Decoding how tissue properties emerge across multiple spatial and temporal scales from the integration of local signals is a grand challenge in quantitative biology. For example, the collective behavior of epithelial cells is critical for shaping dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157fe3d113b8184e4883d7106a37b2f0
https://pubmed.ncbi.nlm.nih.gov/29611534
https://pubmed.ncbi.nlm.nih.gov/29611534
Autor:
Qinfeng Wu, Pavel A. Brodskiy, Lin Yang, Yejia Zhang, Yizhe Zhang, Peixian Liang, Danny Z. Chen, Jianxu Chen, Jeremiah J. Zartman
Publikováno v:
Proc IEEE Int Symp Biomed Imaging
ISBI
ISBI
Wing disc pouches of fruit flies are a powerful genetic model for studying physiological intercellular calcium ($Ca^{2+}$) signals for dynamic analysis of cell signaling in organ development and disease studies. A key to analyzing spatial-temporal pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ac757ec31e71e4ded9b42b704493a9