Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pavel, Yanev"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 1804-1810 (2023)
β-Keto amides were used as convenient precursors to both 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides. The utility of this approach is demonstrated with the synthesis of fourteen novel and four known quinolone derivatives, including n
Externí odkaz:
https://doaj.org/article/1da3f456ce55435eb846651c1d54984e
Autor:
Plamen Angelov, Pavel Yanev
Publikováno v:
Molbank, Vol 2024, Iss 1, p M1778 (2024)
2-Methyl-4-oxo-4,5-dihydro-1H-pyrrole-3-carboxylic acid phenylamide was obtained as a single product in an experiment on the cyclization modes of a glycine-derived enamino amide. High yield and operational simplicity are the main features of the pres
Externí odkaz:
https://doaj.org/article/63eb3b4a3f7f41cfb1d246ec716910b7
Publikováno v:
Molbank, Vol 2022, Iss 1, p M1324 (2022)
3-Carbamoylmethyl-Indole-1-Carboxylic Acid Ethyl Ester (an ethoxycarbonyl derivative of indole-3-acetamide) is obtained by Friedel–Crafts type cyclocondensation of γ-functionalized acetoacetamide in neat polyphosphoric acid.
Externí odkaz:
https://doaj.org/article/8413755d5ae44db79613eb3a063a6b01
Publikováno v:
Acta Chimica Slovenica, Vol 67, Iss 2, Pp 594-601 (2020)
The complex formation between the anionic chelate of molybdenum(VI) with the bidentate ligand of 3,5-dinitrocatechol (3,5-DNC) and its ion-association with the cation of 2,3,5-triphenyl-2Н-tetrazolium chloride (TTC) in the liquid-liquid extraction s
Externí odkaz:
https://doaj.org/article/438a3c47fd4447839c9723178e243351
Publikováno v:
Molbank, Vol 2021, Iss 3, p M1266 (2021)
In a high-yielding and solvent-free procedure N-ethoxycarbonyl protected ω-amino-β-keto anilides undergo Knorr cyclisation in neat polyphosphoric acid to provide straightforward route to 4-aminoalkyl quinolin-2-one derivatives with variable length
Externí odkaz:
https://doaj.org/article/6ce8cfa2587242e9accb3dcbbff3ec31
Synthesis of functionalised β-keto amides by aminoacylation/domino fragmentation of β-enamino amides
Autor:
Pavel Yanev, Plamen Angelov
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2602-2606 (2018)
Ethylenediamine-derived β-enamino amides are used as equivalents of amide enolate synthons in C-acylation reactions with N-protected amino acids. Domino fragmentation of the obtained intermediates leads to functionalised β-keto amides, bearing a pr
Externí odkaz:
https://doaj.org/article/608bd4afa5e84a53956700c9238fcbfc
Publikováno v:
Molbank, Vol 2021, Iss 1, p M1188 (2021)
A new approach for the synthesis of Santacruzamate A analogues is demonstrated. The method allows functionalization at position 3 of the gamma-aminobutyric fragment and carbon chain variation.
Externí odkaz:
https://doaj.org/article/32c5c0eafd4c45f3b611fec382d2fb4e
Autor:
Pavel Yanev, Geralda AF van Tilborg, Annette van der Toorn, Xiangmei Kong, Ann M Stowe, Rick M Dijkhuizen
Publikováno v:
J Cereb Blood Flow Metab
Injectable hydrogels can generate and support pro-repair environments in injured tissue. Here we used a slow-releasing drug carrying in situ-forming hydrogel to promote post-stroke recovery in a rat model. Release kinetics were measured in vitro and
Publikováno v:
Acta Chimica Slovenica, Vol 67, Iss 2, Pp 594-601 (2020)
The complex formation between the anionic chelate of molybdenum(VI) with the bidentate ligand of 3,5-dinitrocatechol (3,5-DNC) and its ion-association with the cation of 2,3,5-triphenyl-2 Н -tetrazolium chloride (TTC) in the liquid-liquid extraction
Publikováno v:
Molbank, Vol 2021, Iss M1266, p M1266 (2021)
In a high-yielding and solvent-free procedure N-ethoxycarbonyl protected ω-amino-β-keto anilides undergo Knorr cyclisation in neat polyphosphoric acid to provide straightforward route to 4-aminoalkyl quinolin-2-one derivatives with variable length