Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Pavel, Lobachevsky"'
Autor:
Pavel Lobachevsky, Helen B. Forrester, Alesia Ivashkevich, Joel Mason, Andrew W. Stevenson, Chris J. Hall, Carl N. Sprung, Valentin G. Djonov, Olga A. Martin
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Synchrotron radiation, especially microbeam radiotherapy (MRT), has a great potential to improve cancer radiotherapy, but non-targeted effects of synchrotron radiation have not yet been sufficiently explored. We have previously demonstrated that scat
Externí odkaz:
https://doaj.org/article/7134005c3d1e4eff8f6c4f102083903a
Autor:
Thomas Fellowes, Colin E. Skene, Roger F. Martin, Pavel Lobachevsky, Tze Cin Owyong, Yuning Hong, Jonathan M. White
Publikováno v:
Arkivoc. 2022:80-98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c924f49ffe653a6d13f3f1f7c5e5d22
https://doi.org/10.24820/ark.5550190.p011.684
https://doi.org/10.24820/ark.5550190.p011.684
Autor:
Olga A. Martin, David Ball, Jai Smith, Nickala Best, Jessica Ventura, Richard J. Lobb, Andreas Möller, Tomas Kron, Michael P. MacManus, Pavel Lobachevsky, Shankar Siva
Mean (+/- SD) Changes in concentration of plasma cytokine levels at baseline, 1-hour, 24-hours and 4-weeks after commencement of RT stratified by use of concurrent chemotherapy. Change at 1-hour in MDC and 4 weeks in MIP-1α is marked with an asteris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f5f1a2e78f5a2bf381e4c1e4e9952d
https://doi.org/10.1158/1078-0432.22468769.v1
https://doi.org/10.1158/1078-0432.22468769.v1
Autor:
Olga A. Martin, David Ball, Jai Smith, Nickala Best, Jessica Ventura, Richard J. Lobb, Andreas Möller, Tomas Kron, Michael P. MacManus, Pavel Lobachevsky, Shankar Siva
Association between PTV volume and excess (above the baseline) average number of foci per cell (a) and excess proportion of cells with {greater than or equal to} 6 γ-H2AX foci (b) at 1-hour and 24-hours.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00a60120ecf93440a970918e059431f
https://doi.org/10.1158/1078-0432.22468772.v1
https://doi.org/10.1158/1078-0432.22468772.v1
Autor:
Olga A. Martin, David Ball, Jai Smith, Nickala Best, Jessica Ventura, Richard J. Lobb, Andreas Möller, Tomas Kron, Michael P. MacManus, Pavel Lobachevsky, Shankar Siva
Purpose: To study the response of irradiated and out-of-field normal tissues during localized curative intent radiotherapy.Experimental Design: Sixteen patients with non–small cell lung carcinoma (NSCLC) received 60 Gy in 30 fractions of definitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f06bfcb106853712a78266fdaaf3e1
https://doi.org/10.1158/1078-0432.c.6527048
https://doi.org/10.1158/1078-0432.c.6527048
Autor:
Olga A. Martin, David Ball, Jai Smith, Nickala Best, Jessica Ventura, Richard J. Lobb, Andreas Möller, Tomas Kron, Michael P. MacManus, Pavel Lobachevsky, Shankar Siva
Changes in exosome concentration in individual patients (particles per mL) over course of treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362cce4b7e8f5006fc692d0b6832fea5
https://doi.org/10.1158/1078-0432.22468766.v1
https://doi.org/10.1158/1078-0432.22468766.v1
Autor:
Andrea J. Smith, Laura Munforte, Jonathan M. White, Colin Skene, Roger F. Martin, Pavel Lobachevsky
Publikováno v:
International Journal of Radiation Biology. 99:95-102
Purpose: The interest in exploiting Auger emitters in cancer therapy stems from their high linear energy transfer (LET)-type radiation damage to DNA. However, the design of Auger-emitter labeled vehicles that target the Auger cascade specifically to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749acd6191d67979c9492679d4d59c40
https://doi.org/10.1080/09553002.2021.1976862
https://doi.org/10.1080/09553002.2021.1976862
Autor:
Jean-Yves Blay, Shivakumar Keerthikumar, Marina Pajic, Simon Junankar, Darren N. Saunders, Uyen Nguyen, Anthony T. Papenfuss, Paul Timpson, Ana Cristina Vargas, David Thomas, David R. Croucher, David L Goode, Danielle Nessem, Alvaro Gonzalez Rajal, Sean C. Warren, Min Ru Qiu, Mark J. McCabe, Georgina V. Long, Justin Bedo, Niall M. Corcoran, Max Nobis, Mark J. Cowley, Pavel Lobachevsky, Daniele Generali, Arcadi Cipponi
Publikováno v:
Science. 368:1127-1131
How cancer cells adapt to stress Bacteria adapt to harsh conditions such as antibiotic exposure by acquiring new mutations, a process called stress-induced mutagenesis. Cipponi et al. investigated whether similar programs of mutagenesis play a role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9fcede3e7a71227c2ed74c18a602b5
https://doi.org/10.1126/science.aau8768
https://doi.org/10.1126/science.aau8768
Autor:
Shankar Siva, Michael MacManus, Tomas Kron, Nickala Best, Jai Smith, Pavel Lobachevsky, David Ball, Olga Martin
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109560 (2014)
Lung inflammation leading to pulmonary toxicity after radiotherapy (RT) can occur in patients with non-small cell lung cancer (NSCLC). We investigated the kinetics of RT induced plasma inflammatory cytokines in these patients in order to identify cli
Externí odkaz:
https://doaj.org/article/7a2521258cca45d98ec9a75536801c6d
Autor:
Carl Norman Sprung, Pavel Lobachevsky, Andrew W. Stevenson, Chris Hall, Helen B. Forrester, Olga A. Martin
Publikováno v:
Radiation Research. 194
Abscopal effects are an important aspect of targeted radiation therapy due to their implication in normal tissue toxicity from chronic inflammatory responses and mutagenesis. Gene expression can be used to determine abscopal effects at the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72483d053a4e16387bd02e4f704a7d2f
https://doi.org/10.1667/rade-19-00014.1
https://doi.org/10.1667/rade-19-00014.1