Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Pavan K. Tandra"'
Autor:
Jairam Krishnamurthy, Jingqin Luo, Rama Suresh, Foluso Ademuyiwa, Caron Rigden, Timothy Rearden, Katherine Clifton, Katherine Weilbaecher, Ashley Frith, Anna Roshal, Pavan K. Tandra, Mathew Cherian, Tracy Summa, Brittney Haas, Shana Thomas, Leonel Hernandez-Aya, Mattias Bergqvist, Lindsey Peterson, Cynthia X. Ma
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract Palbociclib 3-weeks-on/1-week-off, combined with hormonal therapy, is approved for hormone receptor positive (HR+)/HER2-negative (HER2−) advanced/metastatic breast cancer (MBC). Neutropenia is the most frequent adverse event (AE). We aim t
Externí odkaz:
https://doaj.org/article/66f1f8841c624feda0766f004e302bc2
Autor:
Andrew A. Davis, Jingqin Luo, Tiantian Zheng, Chao Dai, Xiaoxi Dong, Lu Tan, Rama Suresh, Foluso O. Ademuyiwa, Caron Rigden, Timothy P. Rearden, Katherine Clifton, Katherine Weilbaecher, Ashley Frith, Pavan K. Tandra, Tracy Summa, Brittney Haas, Shana Thomas, Leonel F. Hernandez-Aya, Lindsay L. Peterson, Xiaohong Wang, Shujun J. Luo, Kemin Zhou, Pan Du, Shidong Jia, Bonnie L. King, Jairam Krishnamurthy, Cynthia X. Ma
Publikováno v:
Clinical Cancer Research. 29:1719-1729
Purpose: Clinical biomarkers to identify patients unlikely to benefit from CDK4/6 inhibition (CDK4/6i) in combination with endocrine therapy (ET) are lacking. We implemented a comprehensive circulating tumor DNA (ctDNA) analysis to identify genomic f
Autor:
Cynthia X. Ma, Jairam Krishnamurthy, Bonnie L. King, Shidong Jia, Pan Du, Kemin Zhou, Shujun J. Luo, Xiaohong Wang, Lindsay L. Peterson, Leonel F. Hernandez-Aya, Shana Thomas, Brittney Haas, Tracy Summa, Pavan K. Tandra, Ashley Frith, Katherine Weilbaecher, Katherine Clifton, Timothy P. Rearden, Caron Rigden, Foluso O. Ademuyiwa, Rama Suresh, Lu Tan, Xiaoxi Dong, Chao Dai, Tiantian Zheng, Jingqin Luo, Andrew A. Davis
Patient demographics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d075bb2d1011b3300fbce290859c63
https://doi.org/10.1158/1078-0432.22725390
https://doi.org/10.1158/1078-0432.22725390
Autor:
Cynthia X. Ma, Jairam Krishnamurthy, Bonnie L. King, Shidong Jia, Pan Du, Kemin Zhou, Shujun J. Luo, Xiaohong Wang, Lindsay L. Peterson, Leonel F. Hernandez-Aya, Shana Thomas, Brittney Haas, Tracy Summa, Pavan K. Tandra, Ashley Frith, Katherine Weilbaecher, Katherine Clifton, Timothy P. Rearden, Caron Rigden, Foluso O. Ademuyiwa, Rama Suresh, Lu Tan, Xiaoxi Dong, Chao Dai, Tiantian Zheng, Jingqin Luo, Andrew A. Davis
Purpose:Clinical biomarkers to identify patients unlikely to benefit from CDK4/6 inhibition (CDK4/6i) in combination with endocrine therapy (ET) are lacking. We implemented a comprehensive circulating tumor DNA (ctDNA) analysis to identify genomic fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0df02d6c6f5748a028ebd817b89c67
https://doi.org/10.1158/1078-0432.c.6533108.v2
https://doi.org/10.1158/1078-0432.c.6533108.v2
Autor:
Cynthia X. Ma, Jairam Krishnamurthy, Bonnie L. King, Shidong Jia, Pan Du, Kemin Zhou, Shujun J. Luo, Xiaohong Wang, Lindsay L. Peterson, Leonel F. Hernandez-Aya, Shana Thomas, Brittney Haas, Tracy Summa, Pavan K. Tandra, Ashley Frith, Katherine Weilbaecher, Katherine Clifton, Timothy P. Rearden, Caron Rigden, Foluso O. Ademuyiwa, Rama Suresh, Lu Tan, Xiaoxi Dong, Chao Dai, Tiantian Zheng, Jingqin Luo, Andrew A. Davis
Gene alterations associated with shorter PFS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc23f4d8d91f1f72b4fad240d1c2b57
https://doi.org/10.1158/1078-0432.22725387.v1
https://doi.org/10.1158/1078-0432.22725387.v1
Autor:
Cynthia X. Ma, Jairam Krishnamurthy, Bonnie L. King, Shidong Jia, Pan Du, Kemin Zhou, Shujun J. Luo, Xiaohong Wang, Lindsay L. Peterson, Leonel F. Hernandez-Aya, Shana Thomas, Brittney Haas, Tracy Summa, Pavan K. Tandra, Ashley Frith, Katherine Weilbaecher, Katherine Clifton, Timothy P. Rearden, Caron Rigden, Foluso O. Ademuyiwa, Rama Suresh, Lu Tan, Xiaoxi Dong, Chao Dai, Tiantian Zheng, Jingqin Luo, Andrew A. Davis
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b074cbc8439407308a3e371e914069e
https://doi.org/10.1158/1078-0432.22725396
https://doi.org/10.1158/1078-0432.22725396
Autor:
Cynthia X. Ma, Jairam Krishnamurthy, Bonnie L. King, Shidong Jia, Pan Du, Kemin Zhou, Shujun J. Luo, Xiaohong Wang, Lindsay L. Peterson, Leonel F. Hernandez-Aya, Shana Thomas, Brittney Haas, Tracy Summa, Pavan K. Tandra, Ashley Frith, Katherine Weilbaecher, Katherine Clifton, Timothy P. Rearden, Caron Rigden, Foluso O. Ademuyiwa, Rama Suresh, Lu Tan, Xiaoxi Dong, Chao Dai, Tiantian Zheng, Jingqin Luo, Andrew A. Davis
PredicineATLAS gene panel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849325c89841e498f7fca70b24fe842f
https://doi.org/10.1158/1078-0432.22725393
https://doi.org/10.1158/1078-0432.22725393
Autor:
Cynthia X. Ma, Jairam Krishnamurthy, Bonnie L. King, Shidong Jia, Pan Du, Kemin Zhou, Shujun J. Luo, Xiaohong Wang, Lindsay L. Peterson, Leonel F. Hernandez-Aya, Shana Thomas, Brittney Haas, Tracy Summa, Pavan K. Tandra, Ashley Frith, Katherine Weilbaecher, Katherine Clifton, Timothy P. Rearden, Caron Rigden, Foluso O. Ademuyiwa, Rama Suresh, Lu Tan, Xiaoxi Dong, Chao Dai, Tiantian Zheng, Jingqin Luo, Andrew A. Davis
DNA sequencing data summary.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff0f5c7818830922bbf428ce4cc483c
https://doi.org/10.1158/1078-0432.22725402
https://doi.org/10.1158/1078-0432.22725402
Autor:
Cynthia X. Ma, Jairam Krishnamurthy, Bonnie L. King, Shidong Jia, Pan Du, Kemin Zhou, Shujun J. Luo, Xiaohong Wang, Lindsay L. Peterson, Leonel F. Hernandez-Aya, Shana Thomas, Brittney Haas, Tracy Summa, Pavan K. Tandra, Ashley Frith, Katherine Weilbaecher, Katherine Clifton, Timothy P. Rearden, Caron Rigden, Foluso O. Ademuyiwa, Rama Suresh, Lu Tan, Xiaoxi Dong, Chao Dai, Tiantian Zheng, Jingqin Luo, Andrew A. Davis
Supplementary Figure S1. High bTMB is associated with the presence of specific mutations. Supplementary Figure S2. ROC analysis to determine optimal bTMB cutoff. Supplementary Figure S3. High correlation between bTMB determined from WES and a 152- ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c78cf09e009ff3d9f7257cff997cf67
https://doi.org/10.1158/1078-0432.22490189.v1
https://doi.org/10.1158/1078-0432.22490189.v1
Autor:
Andrew Davis, Jingqin Luo, Tiantian Zheng, Lu Tan, Amy Wang, Rama Suresh, Foluso Ademuyiwa, Caron Rigden, Timothy Rearden, Katherine Clifton, Katherine Weilbaecher, Ashley Frith, Pavan K Tandra, Tracy Summa, Brittney Haas, Shana Thomas, Leonel Hernandez-Aya, Lindsay Peterson, Shujun Luo, Bonnie L King, Shidong Jia, Jianjun Yu, Pan Du, Jairam Krishnamurthy, Cynthia X Ma, C Dai
Publikováno v:
Cancer Research. 82:P2-07
Background: CDK4/6i combined with ET improves survival for pts with HR+, HER2- MBC. However, biomarkers to predict efficacy and resistance are needed. We hypothesized that a comprehensive next-generation sequencing (NGS)-based liquid biopsy assessmen