Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pavan Auluck"'
Autor:
Sergio Espeso-Gil, Tobias Halene, Jaroslav Bendl, Bibi Kassim, Gabriella Ben Hutta, Marina Iskhakova, Neda Shokrian, Pavan Auluck, Behnam Javidfar, Prashanth Rajarajan, Sandhya Chandrasekaran, Cyril J. Peter, Alanna Cote, Rebecca Birnbaum, Will Liao, Tyler Borrman, Jennifer Wiseman, Aaron Bell, Michael J. Bannon, Panagiotis Roussos, John F. Crary, Zhiping Weng, Stefano Marenco, Barbara Lipska, Nadejda M. Tsankova, Laura Huckins, Yan Jiang, Schahram Akbarian
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-19 (2020)
Abstract Background Midbrain dopaminergic neurons (MDN) represent 0.0005% of the brain’s neuronal population and mediate cognition, food intake, and metabolism. MDN are also posited to underlay the neurobiological dysfunction of schizophrenia (SCZ)
Externí odkaz:
https://doaj.org/article/12c3984af6c44601a2a73a399133c309
Autor:
Laramie Duncan, Hanyang Shen, Anton Schulmann, Tayden Li, Bhaskar Kolachana, Ajeet Mandal, Ningping Feng, Pavan Auluck, Stefano Marenco
Publikováno v:
Neuropsychopharmacology. 48:764-772
A new era of human postmortem tissue research has emerged thanks to the development of ‘omics technologies that measure genes, proteins, and spatial parameters in unprecedented detail. Also newly possible is the ability to construct polygenic score
Autor:
Biao Zeng, Jaroslav Bendl, Chengyu Deng, Donghoon Lee, Ruth Misir, Sarah M. Reach, Steven P. Kleopoulos, Pavan Auluck, Stefano Marenco, David A. Lewis, Vahram Haroutunian, Nadav Ahituv, John F. Fullard, Gabriel E. Hoffman, Panos Roussos
Nucleotide variants in cell type-specific gene regulatory elements in the human brain are major risk factors of human disease. We measured chromatin accessibility in sorted neurons and glia from 1,932 samples of human postmortem brain and identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77d92cb067b31030eb4fbee22de506be
https://doi.org/10.1101/2023.03.02.530826
https://doi.org/10.1101/2023.03.02.530826
Autor:
C. Harker Rhodes, Barbara K. Lipska, Sevilla D. Detera-Wadleigh, Qing Xu, Kory R. Johnson, Pavan Auluck, Bryce England, Jose A. Apud, Aparna Nathan, Brent T. Harris, Stefano Marenco, Kwangmi An, Robin Kramer, Winston Corona, Francis J. McMahon, Joanna Cross, Kevin Zhu, Anton Schulmann, Nirmala Akula, Ningping Feng, Xueying Jiang
Publikováno v:
Neuropsychopharmacology
Despite strong evidence of heritability and growing discovery of genetic markers for major mental illness, little is known about how gene expression in the brain differs across psychiatric diagnoses, or how known genetic risk factors shape these diff
Autor:
Hanyang Shen, Anton Schulmann, Tayden Li, Bhaskar Kolachana, Ajeet Mandal, Ningping Feng, Pavan Auluck, Stefano Marenco, Laramie Duncan
Publikováno v:
European Neuropsychopharmacology. 63:e301-e302
Autor:
Anton Schulmann, Stefano Marenco, Pavan Auluck, Ningping Feng, Qing Xu, Nirmala Akula, Barbara Lipska, Francis McMahon
Publikováno v:
Biological Psychiatry. 91:S282-S283
Autor:
Yan Jiang, Tyler M. Borrman, Jennifer Wiseman, Gabriella Hutta, Tobias B. Halene, Cyril J. Peter, Nadejda M. Tsankova, Pavan Auluck, John F. Crary, Sergio Espeso-Gil, Neda Shokrian, Jaroslav Bendl, Behnam Javidfar, Alanna C. Cote, Sandhya Chandrasekaran, Schahram Akbarian, Stefano Marenco, Michael J. Bannon, Panagiotis Roussos, Aaron J Bell, Rebecca Birnbaum, Bibi Kassim, Barbara K. Lipska, Prashanth Rajarajan, Laura M. Huckins, Will Liao, Marina Iskhakova, Zhiping Weng
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-19 (2020)
Genome Medicine
Genome Medicine
Background Midbrain dopaminergic neurons (MDN) represent 0.0005% of the brain’s neuronal population and mediate cognition, food intake, and metabolism. MDN are also posited to underlay the neurobiological dysfunction of schizophrenia (SCZ), a sever
Autor:
Chee W. Chia, Jennifer F. O’Connell, Pavan Auluck, Luigi Ferrucci, Qinghua Chen, Stefano Marenco, Min Zhu, Josephine M. Egan, Nicholas S. Huang, Caio Henrique Mazucanti, Pingbo Zhang, Doyle Lu Lang, Qing-Rong Liu
Publikováno v:
Diabetes
Human insulin (INS) gene diverged from the ancestral genes of invertebrate and mammalian species millions of years ago. We previously found that mouse insulin gene (Ins2) isoforms are expressed in brain choroid plexus (ChP) epithelium cells where ins
Autor:
Himanshu Naik, Lauren Stevenson, Alex Pellerin, Pavan Auluck, Victoria P. Werth, Dania Rabah, Taylor L. Reynolds, Richard Furie, Romy Christmann, Nathalie Franchimont, Agnes Gardet, Joseph F. Merola, C. Barbey, Stefan Hamann, Parul Gulati, Wenting Wang
Publikováno v:
Journal of Clinical Investigation. 129:1359-1371
BACKGROUND. Plasmacytoid DCs (pDC) produce large amounts of type I IFN (IFN-I), cytokines convincingly linked to systemic lupus erythematosus (SLE) pathogenesis. BIIB059 is a humanized mAb that binds blood DC antigen 2 (BDCA2), a pDC-specific recepto
Autor:
Pavan Auluck, Amna Zehra, David Goldman, Nora D. Volkow, Ningping Feng, Christine Muench, Gene-Jack Wang, Hui Sun, Corinde E. Wiers, Stefano Marenco, Falk W. Lohoff, Jisoo Lee, Clara Freeman, James M. Swanson, Barbara K. Lipska
Publikováno v:
European Journal of Neuroscience. 48:1884-1895
Dopamine transporters (DAT) are implicated in the pathogenesis and treatment of attention deficit hyperactivity disorder (ADHD) and are upregulated by chronic treatment with methylphenidate, commonly prescribed for ADHD. Methylation of the DAT1 gene