DEGRADADORES DE HISTONA DEACETILASE PARA INDUÇÃO DE HEMOGLOBINA FETAL

Autor: Pavan, AR, Pastre, VGF, Lanaro, C, Albuquerque, DM, Smalley, JP, Patel, U, Schwabe, JWR, Cowley, SM, Hodgkinson, JT, Santos, JLD, Costa, FF

Publikováno v: In Hematology, Transfusion and Cell Therapy October 2024 46 Supplement 4:S40-S41

Clinical Pharmacology: Epigenetic Drugs at a Glance

Autor: Dos Santos Fernandes Gf, Pavan Ar, Dos Santos Jl

Publikováno v: Biochemistry & Pharmacology: Open Access.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50a715e716234d9da0ba3a3439fa6410
https://doi.org/10.4172/2167-0501.1000e186

Cereblon-recruiting proteolysis targeting chimeras (PROTACs) can determine the selective degradation of HDAC1 over HDAC3.

Autor: Pavan AR; Leicester Institute of Structural and Chemical Biology and School of Chemistry, University of Leicester, University Road, Leicester, LE1 7RH, UK. JTHodgkinson@le.ac.uk., Smalley JP; Leicester Institute of Structural and Chemical Biology and School of Chemistry, University of Leicester, University Road, Leicester, LE1 7RH, UK. JTHodgkinson@le.ac.uk., Patel U; Leicester Institute of Structural and Chemical Biology and School of Chemistry, University of Leicester, University Road, Leicester, LE1 7RH, UK. JTHodgkinson@le.ac.uk., Pytel WA; Leicester Institute of Structural and Chemical Biology and School of Chemistry, University of Leicester, University Road, Leicester, LE1 7RH, UK. JTHodgkinson@le.ac.uk., Dos Santos JL; São Paulo State University (UNESP), School of Pharmaceutical Sciences, Araraquara, Brazil. jean.santos@unesp.br., Cowley SM; A Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 9HN, UK. smc57@leicester.ac.uk., Schwabe JWR; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 9HN, UK. john.schwabe@le.ac.uk., Hodgkinson JT; Leicester Institute of Structural and Chemical Biology and School of Chemistry, University of Leicester, University Road, Leicester, LE1 7RH, UK. JTHodgkinson@le.ac.uk.

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Nov 05. Date of Electronic Publication: 2024 Nov 05.

In vitro and In vivo Activity of a New N-Oxide Derivative for Acne Vulgaris Treatment.

Autor: Delgado ILL; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil., Scarim CB; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil., Fernandes FHA; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil., Barbieri KP; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil., Polesi MC; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil., Pavan AR; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil.; Institute of Chemistry, São Paulo State University (UNESP), Francisco Degni 55, Araraquara, 14800060, Brazil., Chiba DE; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil., Salgado HRN; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil., Carlos IZ; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil., Corrêa MA; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil., de Andrade CR; School of Dentistry, São Paulo State University (UNESP), R. Humaitá 1680, Araraquara, 14801-385, Brazil., Dos Santos JL; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Rod. Araraquara-Jaú, Araraquara, 14800-903, Brazil.

Publikováno v: Medicinal chemistry (Shariqah (United Arab Emirates)) [Med Chem] 2024 Jul 30. Date of Electronic Publication: 2024 Jul 30.

BacPROTACs targeting Clp protease: a promising strategy for anti-mycobacterial drug discovery.

Autor: Bonjorno AF; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil., Pavan AR; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.; Institute of Chemistry, São Paulo State University (UNESP), Araraquara, Brazil., Fernandes GFS; Department of Chemistry, University College London, London, United Kingdom., Scarim CB; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil., Castagnolo D; Department of Chemistry, University College London, London, United Kingdom., Dos Santos JL; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.

Publikováno v: Frontiers in chemistry [Front Chem] 2024 Jan 31; Vol. 12, pp. 1358539. Date of Electronic Publication: 2024 Jan 31 (Print Publication: 2024).