Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Pavak K. Shah"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 12, p e1011733 (2023)
High throughput experimental approaches are increasingly allowing for the quantitative description of cellular and organismal phenotypes. Distilling these large volumes of complex data into meaningful measures that can drive biological insight remain
Externí odkaz:
https://doaj.org/article/9ea2a6711c0f49cd985cafa177998254
Autor:
Daan Vorselen, Yifan Wang, Miguel M. de Jesus, Pavak K. Shah, Matthew J. Footer, Morgan Huse, Wei Cai, Julie A. Theriot
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Traction force microscopy is an effective method for measuring cellular forces but it is limited by planar geometry. Here the authors develop a facile method to produce deformable hydrogel particles and a reference-free computational method to resolv
Externí odkaz:
https://doaj.org/article/fbc3f6afb17f46f49e6de46d02f86e78
Autor:
Pavak K. Shah, Alina Rashid, Yun Lu, Shai Shaham, Anupriya Singhal, Zhirong Bao, Meera Trivedi, Peter Insley, Piya Ghose
Publikováno v:
Nature Cell Biology. 20:393-399
Phagocytosis of dying cells is critical in development and immunity1-3. Although proteins for recognition and engulfment of cellular debris following cell death are known4,5, proteins that directly mediate phagosome sealing are uncharacterized. Furth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d0f807ab7e15b8463136b9f7a90dc0
https://doi.org/10.1038/s41556-018-0068-5
https://doi.org/10.1038/s41556-018-0068-5
Autor:
Julie A. Theriot, de Jesus Mm, Yuebing Wang, Morgan Huse, Wei Cai, Pavak K. Shah, Daan Vorselen, Matthew J. Footer
Force exertion is an integral part of cellular behavior. Traction force microscopy (TFM) has been instrumental for studying such forces, providing both spatial and directional force measurements at subcellular resolution. However, the applications of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5125c793c906fb1161fb516834e1fab
https://doi.org/10.1101/431221
https://doi.org/10.1101/431221
Autor:
Pavak K. Shah, Nancy L. Allbritton, Jen Jen Yeh, Silvia Gabriela Herrera-Loeza, Christopher E. Sims
Publikováno v:
Cytometry Part A. 85:642-649
Primary patient samples are the gold standard for molecular investigations of tumor biology yet are difficult to acquire, heterogeneous in nature and variable in size. Patient-derived xenografts (PDXs) comprised of primary tumor tissue cultured in ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abc796c65bafbc410d707eb08047dd14
https://doi.org/10.1002/cyto.a.22480
https://doi.org/10.1002/cyto.a.22480
Publikováno v:
Integr. Biol.. 6:673-684
Wnt/β-catenin signaling is of significant interest due to the roles it plays in regulating development, tissue regeneration and disease. Transcriptional reporters have been widely employed to study Wnt/β-catenin signal transduction in live cells an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c142f905fc3dbe4c4519c70efe7068b4
https://doi.org/10.1039/c4ib00050a
https://doi.org/10.1039/c4ib00050a
Publikováno v:
Analytical Chemistry. 85:4991-4997
Microfluidic systems show great promise for single-cell analysis; however, as these technologies mature, their utility must be validated by studies of biologically relevant processes. An important biomedical application of these systems is characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc55499276325f4b6e89ac22fa9b648
https://doi.org/10.1021/ac4002029
https://doi.org/10.1021/ac4002029
Autor:
Yuli Wang, Adam T. Melvin, Michelle L. Kovarik, Alexandra J. Dickinson, Philip C. Gach, Douglas M. Ornoff, Nancy L. Allbritton, Nicholas C. Dobes, Pavak K. Shah
Publikováno v:
Analytical Chemistry. 85:451-472
Applications of micro total analysis systems (μTAS) span basic-science research, clinical medicine, and field work. Assay devices designed for these applications offer improvements to existing methods or provide fundamentally new strategies. Both ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f687e67a7d316f9f7ad7dc1a7a3245
https://doi.org/10.1021/ac3031543
https://doi.org/10.1021/ac3031543
Publikováno v:
Analytical and Bioanalytical Chemistry. 402:1065-1072
There is a need for a technology that can be incorporated into routine laboratory procedures to obtain a continuous, quantitative, fluorescence-based measurement of the dynamic behaviors of numerous individual living cells in parallel, while allowing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6971dec2976133d607e87ee12280c955
https://doi.org/10.1007/s00216-011-5535-9
https://doi.org/10.1007/s00216-011-5535-9
Autor:
Zhirong Bao, Ismar Kovacevic, Daniel A. Colón-Ramos, Abhishek Kumar, Raúl Catena, Yicong Wu, Javier Marquina-Solis, Pavak K. Shah, Zidong Yu, James C. Schaff, William A. Mohler, Hari Shroff, Anthony Santella
Publikováno v:
BMC Bioinformatics
Background Imaging and image analysis advances are yielding increasingly complete and complicated records of cellular events in tissues and whole embryos. The ability to follow hundreds to thousands of cells at the individual level demands a spatio-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d585f5eb13357f7b07ffe44f668421
https://pubmed.ncbi.nlm.nih.gov/26051157
https://pubmed.ncbi.nlm.nih.gov/26051157