Switching the Chemoselectivity in the Preparation of [¹⁸F]FNA‑N‑CooP, a Free Thiol-Containing Peptide for Targeted Positron Emission Tomography Imaging of Fatty Acid Binding Protein 3.

Autor: Dillemuth, Pyry, Lövdahl, Petter, Karskela, Tuomas, Ayo, Abiodun, Ponkamo, Jesse, Liljenbäck, Heidi, Paunonen, Sami, Kunnas, Jonne, Rajander, Johan, Tynninen, Olli, Rosenholm, Jessica M., Roivainen, Anne, Laakkonen, Pirjo, Airaksinen, Anu J., Li, Xiang-Guo

Publikováno v: Molecular Pharmaceutics; 8/5/2024, Vol. 21 Issue 8, p4147-4156, 10p

Switching the Chemoselectivity in the Preparation of [ ¹⁸ F]FNA- N -CooP, a Free Thiol-Containing Peptide for Targeted Positron Emission Tomography Imaging of Fatty Acid Binding Protein 3.

Autor: Dillemuth P; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Department of Chemistry, University of Turku, Henrikinkatu 2, Turku FI-20500, Finland., Lövdahl P; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Tykistökatu 6, Turku FI-20520, Finland., Karskela T; Turku Centre for Chemical and Molecular Analytics, Åbo Akademi University and University of Turku, Henrikinkatu 2, Turku FI-20500, Finland., Ayo A; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Haartmaninkatu 4, Helsinki FI-00290, Finland., Ponkamo J; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Department of Chemistry, University of Turku, Henrikinkatu 2, Turku FI-20500, Finland., Liljenbäck H; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Turku Center for Disease Modeling, University of Turku, Kiinamyllynkatu 10, Turku FI-20520, Finland., Paunonen S; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Department of Chemistry, University of Turku, Henrikinkatu 2, Turku FI-20500, Finland., Kunnas J; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Tykistökatu 6, Turku FI-20520, Finland., Rajander J; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Accelerator Laboratory, Åbo Akademi University, Kiinamyllynkatu 4-8, Turku FI-20520, Finland., Tynninen O; Department of Pathology, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4, Helsinki FI-00290, Finland., Rosenholm JM; Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Tykistökatu 6, Turku FI-20520, Finland., Roivainen A; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Turku Center for Disease Modeling, University of Turku, Kiinamyllynkatu 10, Turku FI-20520, Finland.; InFLAMES Research Flagship, University of Turku, Tykistökatu 6, Turku FI-20520, Finland., Laakkonen P; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Haartmaninkatu 4, Helsinki FI-00290, Finland.; Laboratory Animal Centre, HiLIFE University of Helsinki, Haartmaninkatu 4, Helsinki FI-00290, Finland.; iCAN Flagship Program, University of Helsinki, Haartmaninkatu 4, Helsinki FI-00290, Finland., Airaksinen AJ; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Department of Chemistry, University of Turku, Henrikinkatu 2, Turku FI-20500, Finland., Li XG; Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.; Department of Chemistry, University of Turku, Henrikinkatu 2, Turku FI-20500, Finland.; InFLAMES Research Flagship, University of Turku, Tykistökatu 6, Turku FI-20520, Finland.; Turku PET Centre, Turku University Hospital, Kiinamyllynkatu 4-8, Turku FI-20520, Finland.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2024 Aug 05; Vol. 21 (8), pp. 4147-4156. Date of Electronic Publication: 2024 Jul 15.