Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Paulraj, Kanmani"'
Autor:
Paulraj Kanmani, Hojun Kim
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262767 (2022)
Hepatic fibrosis is caused by the increased accumulation and improper degradation of extracellular matrix (ECM) proteins in the liver. Hepatic stellate cells (HSCs) activation is a key process in initiating hepatic fibrosis and can be ameliorated by
Externí odkaz:
https://doaj.org/article/6ecfd62e56dc4a17b58cf18df9e36648
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L596-L608
Inflammasome activation is of central importance for the process of generation of overwhelming inflammatory response and the pathogenesis of sepsis. The intrinsic molecular mechanism for controlling inflammasome activation is still poorly understood.
Autor:
Paulraj Kanmani, Hojun Kim
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229647 (2020)
Probiotic bacteria have the ability to modulate host immune responses and have potent therapeutic functional effects against several diseases, including inflammatory diseases. However, beneficial effects of probiotics are strain specific and their in
Externí odkaz:
https://doaj.org/article/69a8425df6de4e5ca88376ca6142cadf
Autor:
Fernanda Raya Tonetti, Mikado Tomokiyo, Ramiro Ortiz Moyano, Sandra Quilodrán-Vega, Hikari Yamamuro, Paulraj Kanmani, Vyacheslav Melnikov, Shoichiro Kurata, Haruki Kitazawa, Julio Villena
Publikováno v:
Microorganisms, Vol 9, Iss 6, p 1324 (2021)
Previously, we demonstrated that the nasal administration of Dolosigranulum pigrum 040417 differentially modulated the respiratory innate immune response triggered by the activation of Toll-like receptor 2 in infant mice. In this work, we aimed to ev
Externí odkaz:
https://doaj.org/article/4f8d0e51c74b4d17b754748dd41a2b37
Autor:
Paulraj Kanmani, Hojun Kim
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Many studies have demonstrated that immunobiotics with immunoregulatory functions improve the outcomes of several bacterial and viral infections by modulating the mucosal immune system. However, the precise mechanisms underlying the immunoregulatory
Externí odkaz:
https://doaj.org/article/93a2f0a53f66473488810f5e0df62054
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Hepatic inflammation and injury may result from the translocation of pathological bacteria and their proinflammatory mediators. Probiotics attenuate hepatic diseases related to inflammation by exhibiting immunoregulatory effects. Therefore, this stud
Externí odkaz:
https://doaj.org/article/771f09abb87b40e7b22165e07c5da2a7
Publikováno v:
Biomedicines, Vol 8, Iss 11, p 501 (2020)
The gut–liver axis plays important roles in both the maintenance of a healthy liver and the pathogenesis of liver diseases, where the gut microbiota acts as a major determinant of this relationship. Gut bacteria-derived metabolites and cellular com
Externí odkaz:
https://doaj.org/article/1daca7b9551f406484405d853ec16525
Autor:
Ramiro Ortiz Moyano, Fernanda Raya Tonetti, Mikado Tomokiyo, Paulraj Kanmani, María Guadalupe Vizoso-Pinto, Hojun Kim, Sandra Quilodrán-Vega, Vyacheslav Melnikov, Susana Alvarez, Hideki Takahashi, Shoichiro Kurata, Haruki Kitazawa, Julio Villena
Publikováno v:
Microorganisms, Vol 8, Iss 5, p 727 (2020)
We investigated whether the ability of commensal respiratory bacteria to modulate the innate immune response against bacterial and viral pathogens was a shared or strain-specific characteristic. Bacterial strains belonging to the Corynebacterium pseu
Externí odkaz:
https://doaj.org/article/5f97cbbed58641238472b3292d763f99
Autor:
Paulraj Kanmani, Leonardo Albarracin, Hisakazu Kobayashi, Elvira Maria Hebert, Lucila Saavedra, Ryoya Komatsu, Brian Gatica, Ayako Miyazaki, Wakako Ikeda-Ohtsubo, Yoshihito Suda, Hisashi Aso, Shintaro Egusa, Takashi Mishima, Alexis Salas-Burgos, Hideki Takahashi, Julio Villena, Haruki Kitazawa
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
In lactic acid bacteria, the synthesis of exopolysaccharides (EPS) has been associated with some favorable technological properties as well as health-promoting benefits. Research works have shown the potential of EPS produced by lactobacilli to diffe
Externí odkaz:
https://doaj.org/article/8505c63785204a818e78e766ad521bfc
Autor:
Paulraj Kanmani, Hojun Kim
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The beneficial effects of probiotics in several liver diseases have been investigated in both animal and clinical models; however, the precise mechanisms responsible for their effects have not yet been elucidated. Gut transmitted endotoxins such as L
Externí odkaz:
https://doaj.org/article/b40f74ec2140416e949be6419da7112a