Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paulo S. A. Augusto"'
Autor:
Raissa Lima Gonçalves Pereira, Angélica Faleiros da Silva Maia, Frederico Duarte Garcia, Felipe T. Martins, Gisele Assis Castro Goulart, Adriana M. Godin, Paulo S. A. Augusto, Leonardo da Silva Neto, Rosemeire B. Alves, Ângelo de Fátima, Valbert Nascimento Cardoso, Sordaini M. Caligiorne, Simone Odília Antunes Fernandes, Maila de Castro Lourenço das Neves
Publikováno v:
Journal of Advanced Research. 38:285-298
Introduction Cocaine use disorder is a significant public health issue without a current specific approved treatment. Among different approaches to this disorder, it is possible to highlight a promising immunologic strategy in which an immunogenic ag
Autor:
Felipe F. Rodrigues, Tamires C. Matsui, Carla R.A. Batista, Márcio M. Coelho, Ivo S.F. Melo, Paulo S. A. Augusto, Renes R. Machado, Marcela M.G.B. Dutra, Alysson Vinícius Braga, Sarah O.A.M. Costa, Caryne M. Bertollo, Marcela I. Morais
Publikováno v:
Inflammopharmacology. 30:233-241
Metformin is an oral hypoglycemic drug widely used in the management of type 2 diabetes mellitus. We have recently demonstrated that metformin exhibits activity in models of nociceptive and neuropathic pain. However, little is known about its effects
Autor:
Paulo S A, Augusto, Tamires C, Matsui, Alysson V, Braga, Felipe F, Rodrigues, Marcela I, Morais, Marcela M G B, Dutra, Carla R A, Batista, Ivo S F, Melo, Sarah O A M, Costa, Caryne M, Bertollo, Márcio M, Coelho, Renes R, Machado
Publikováno v:
Inflammopharmacology. 30(1)
Metformin is an oral hypoglycemic drug widely used in the management of type 2 diabetes mellitus. We have recently demonstrated that metformin exhibits activity in models of nociceptive and neuropathic pain. However, little is known about its effects
Autor:
Maila de Castro Lourenço das Neves, Sordaini M. Caligiorne, Frederico Duarte Garcia, Brian Sabato, Karine Dias Dos Reis, Larissa Pires do Espírito Santo, Gisele Assis Castro Goulart, Raissa Lima Gonçalves Pereira, Paulo S. A. Augusto, Ângelo de Fátima, Bruna Rodrigues Dias Assis
Publikováno v:
Molecular psychiatry. 26(12)
Protecting children from prenatal cocaine exposure is a significant challenge for physicians and childbearing women with cocaine use disorder. Cocaine use is highly prevalent among reproductive-aged women and prenatal cocaine exposure produces obstet
Autor:
Fábio C. Costa, Marcela I. Morais, Ivo S.F. Melo, Paulo S. A. Augusto, Márcio M. Coelho, Ângelo de Fátima, Franciele A. Goulart, Felipe F. Rodrigues, Renes R. Machado, Marcela M.G.B. Dutra, Sarah O.A.M. Costa
Publikováno v:
European Journal of Pharmacology. 824:108-114
Recently, we demonstrated that nicorandil exhibits activities in models of inflammatory and nociceptive pain. In the present study, we extended this investigation by evaluating the effects of nicorandil in models of neuropathic pain induced by paclit
Autor:
Marcela I. Morais, Raquel R. Menezes, Felipe F. Rodrigues, Márcio M. Coelho, Sarah O.A.M. Costa, Ivo S.F. Melo, Marcela G.M.B. Dutra, Ana Mercy S. Brito, Renes R. Machado, Franciele A. Goulart, Paulo S. A. Augusto, Adriana M. Godin
Publikováno v:
European Journal of Pharmacology. 818:17-25
Leflunomide, an immunosuppressive drug approved for the treatment of patients with rheumatoid arthritis, exhibits many mechanisms which may affect the nociceptive processing. Therefore, the present study aimed to evaluate the effect induced by leflun
Autor:
Márcio M. Coelho, Paulo S. A. Augusto, Felipe F. Rodrigues, Fábio C. Costa, Marcela I. Morais, Sarah O.A.M. Costa, Renes R. Machado, Ivo S.F. Melo, Marcela M.G.B. Dutra, Alysson Vinícius Braga, Franciele A. Goulart
Publikováno v:
Inflammopharmacology. 28(2)
Clindamycin, a bacteriostatic semisynthetic lincosamide, is useful in the management of infections caused by aerobic and anaerobic Gram-positive cocci, including bacteremic pneumonia, streptococcal toxic shock syndrome and sepsis. It has been recentl
Autor:
André Klein, Isabela Costa César, Giovanna M.E. Coura, Tamires C. Matsui, Danielle G. Souza, Lucas S. Ribeiro, Renes R. Machado, Adriana M. Godin, Paulo S. A. Augusto, Ivo S.F. Melo, Débora P. Araújo, Ângelo de Fátima, Márcio M. Coelho, Carla R.A. Batista
Publikováno v:
European Journal of Pharmacology. 769:306-312
Nicorandil is a drug characterized by the coupling of a nitric oxide (NO) donor to nicotinamide. We have previously demonstrated that nicotinamide exhibits activity in different models of pain and inflammation. Now, we investigated the effects induce
Autor:
Paulo S. A. Augusto, Alysson Vinícius Braga, Sarah O.A.M. Costa, Marcela I. Morais, Renes R. Machado, Márcio M. Coelho, Marcela M.G.B. Dutra, Ivo S.F. Melo, Franciele A. Goulart, Felipe F. Rodrigues, Carla R.A. Batista
Publikováno v:
European Journal of Pharmacology. 858:172497
Metformin, an AMP-activated protein kinase (AMPK) activator, is an oral hypoglycemic drug widely used to treat patients with type 2 diabetes. As AMPK plays a role in the nociceptive processing, investigating the effects induced by metformin in experi
Autor:
Paulo S. A. Augusto, de Fátima Â, Márcio M. Coelho, Nascimento Júnior Eb, Ana Mercy S. Brito, Adriana M. Godin, Felipe F. Rodrigues, Débora P. Araújo, Renes R. Machado, Ivo S.F. Melo, Dutra Mm
Publikováno v:
European journal of pharmacology. 768
We have previously demonstrated that nicorandil inhibits the second phase of the nociceptive response induced by formaldehyde. In the present study, we evaluated the effects induced by nicorandil in other models of nociceptive and inflammatory pain i