Výsledky vyhledávání - "Paulo S L Oliveira"

Akademický článek

Structural insights into human peroxisome proliferator activated receptor delta (PPAR-delta) selective ligand binding.

Autor: Fernanda A H Batista, Daniela B B Trivella, Amanda Bernardes, Joyce Gratieri, Paulo S L Oliveira, Ana Carolina M Figueira, Paul Webb, Igor Polikarpov

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e33643 (2012)

Peroxisome proliferator activated receptors (PPARs δ, α and γ) are closely related transcription factors that exert distinct effects on fatty acid and glucose metabolism, cardiac disease, inflammatory response and other processes. Several groups d

Externí odkaz: https://doaj.org/article/06b81dbcc279432f99c6d5ec69050fc7

Zobrazit plný text záznamu

Akademický článek

Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds

Publikováno v: Virulence, Vol 13, Iss 1, Pp 1031-1048 (2022)

The ongoing COVID-19 pandemic caused a significant loss of human lives and a worldwide decline in quality of life. Treatment of COVID-19 patients is challenging, and specific treatments to reduce COVID-19 aggravation and mortality are still necessary

Externí odkaz: https://doaj.org/article/72c2c6f47ab64b468b8394b05cb4b8c0

Zobrazit plný text záznamu

Akademický článek

Identification of Compounds With Antiviral Activity Against SARS-CoV-2 in the MMV Pathogen Box Using a Phenotypic High-Throughput Screening Assay

Autor: Laís D. Coimbra, Alexandre Borin, Marina Fontoura, Humberto D. Gravina, Alice Nagai, Jacqueline Farinha Shimizu, Karina Bispo-dos-Santos, Fabiana Granja, Paulo S. L. Oliveira, Kleber G. Franchini, Kirandeep Samby, Marjorie Bruder, José Luiz Proença-Módena, Daniela B. B. Trivella, Juliana H. C. Smetana, Artur T. Cordeiro, Rafael Elias Marques

Publikováno v: Frontiers in Virology, Vol 2 (2022)

Until December 2021, the COVID-19 pandemic has caused more than 5.5 million deaths. Vaccines are being deployed worldwide to mitigate severe disease and death, but continued transmission and the emergence of SARS-CoV-2 variants indicate that specific

Externí odkaz: https://doaj.org/article/a5ef3494e053423bab15254c1229c102

Zobrazit plný text záznamu

Effect of Sex on Vascular Adaptations to Isometric Handgrip Training in Elderly Patients with Peripheral Artery Disease: A Randomized Controlled Trial

Autor: Marilia de Almeida Correia, Gabriel Grizzo Cucato, Nelson Wolosker, Raphael Mendes Ritti-Dias, Paulo S. L. Oliveira, Lauro C. Vianna

Publikováno v: Journal of Vascular Research. 58:388-391

Background: Isometric handgrip training (IHT) promotes vascular adaptations in different populations. Aims: We assessed the sex differences in vascular adaptations of IHT in a sample of older adults with symptomatic peripheral artery disease (PAD). M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa6d7b198fc3a71bdeac4f8fdb1e37aa
https://doi.org/10.1159/000516499

Zobrazit plný text záznamu

Effects of Isometric Handgrip Training in Patients With Peripheral Artery Disease: A Randomized Controlled Trial

Autor: Marilia de Almeida Correia, Gabriel Grizzo Cucato, Raphael Mendes Ritti-Dias, Paulo S. L. Oliveira, Daniel J. Green, Breno Quintella Farah, Lauro C. Vianna, Pedro Puech-Leao, Nelson Wolosker

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Background Meta‐analyses have shown that isometric handgrip training ( IHT ) can reduce brachial systolic and diastolic blood pressure ( BP ) by >6/4 mm Hg, respectively. However, whether IHT promotes these effects among patients with peripheral ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324c76134f48c8aa43ed12ff03ad6d00
http://europepmc.org/articles/PMC7070219

Zobrazit plný text záznamu

Long-range correlation studies in deep earthquakes global series

Autor: Andrés R. R. Papa, Renato Pereira de Freitas, Douglas S. R. Ferreira, Jennifer Ribeiro, André Rocha Pimenta, Paulo S. L. Oliveira

Publikováno v: Physica A: Statistical Mechanics and its Applications. 560:125146

In the present paper we have conducted studies on seismological properties using worldwide data of deep earthquakes (depth larger than 70 km), considering events with magnitude greater than or equal to 4.5. This work is an extension of a previous stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2182e49aa60164fb4dc75cff23cabb22
https://doi.org/10.1016/j.physa.2020.125146

Zobrazit plný text záznamu

Generating Conformation-Specific Polyclonal and Monoclonal Anti-Protein Kinase C Antibodies and Anti-Active State Specific PKC Antibodies

Autor: Darlene A, Pena, Denise M V, Pacheco, Paulo S L, Oliveira, Maria J M, Alves, Deborah, Schechtman

Publikováno v: Current protocols in chemical biology. 10(2)

The protein kinase C (PKC) family of serine/ threonine kinases has been shown to play active roles as either suppressors or promoters of carcinogenesis in different types of tumors. Using antibodies that preferentially recognize the active conformati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4edf552d41cc94097a0545c3cd1f1b27
https://pubmed.ncbi.nlm.nih.gov/29927112

Zobrazit plný text záznamu

Molecular Mechanisms Associated with Xylan Degradation by Xanthomonas Plant Pathogens

Autor: Leandro H.P. Assis, Letícia Maria Zanphorlin, Roberto Ruller, Rodrigo V. Honorato, Mário T. Murakami, Vanesa Peixoto de Matos Martins, Paulo S. L. Oliveira, Camila R. Santos, Zaira B. Hoffmam

Publikováno v: Journal of Biological Chemistry. 289:32186-32200

Xanthomonas pathogens attack a variety of economically relevant plants, and their xylan CUT system (carbohydrate utilization with TonB-dependent outer membrane transporter system) contains two major xylanase-related genes, xynA and xynB, which influe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d193f2e0ff82a3dbd1b3e288b6a9a41a
https://doi.org/10.1074/jbc.m114.605105

Zobrazit plný text záznamu

Revisiting protein kinase–substrate interactions: toward therapeutic development

Autor: Paulo S. L. Oliveira, Felipe Augusto Nunes Ferraz, Darlene Aparecida Pena, Dimitrius T. Pramio, Felipe Alves Morais, Deborah Schechtman

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Despite the efforts of pharmaceutical companies to develop specific kinase modulators, few drugs targeting kinases have been completely successful in the clinic. This is primarily due to the conserved nature of kinases, especially in the catalytic do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bb9357dc497fbaf3a1a34f164e0b48

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání