Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Paulo R. L. Machado"'
Improved Treatment Outcome Following the Use of a Wound Dressings in Cutaneous Leishmaniasis Lesions
Autor:
Pedro B. Borba, Jamile Lago, Tainã Lago, Mariana Araújo-Pereira, Artur T. L. Queiroz, Hernane S. Barud, Lucas P. Carvalho, Paulo R. L. Machado, Edgar M. Carvalho, Camila I. de Oliveira
Publikováno v:
Pathogens, Vol 13, Iss 5, p 416 (2024)
Leishmaniasis, caused by Leishmania parasites, is a neglected tropical disease and Cutaneous Leishmaniasis (CL) is the most common form. Despite the associated toxicity and adverse effects, Meglumine antimoniate (MA) remains the first-choice treatmen
Externí odkaz:
https://doaj.org/article/5ae325d1c88b4d71a59bd80e470a47ae
Publikováno v:
Pathogens, Vol 13, Iss 4, p 301 (2024)
Cutaneous leishmaniasis (CL), caused by Leishmania braziliensis, in recent decades has shown decreasing cure rates after treatment with meglumine antimoniate (MA). Granulocyte colony-stimulating factor (G-CSF) is a cytokine associated with epithelial
Externí odkaz:
https://doaj.org/article/512c1caef4604c8f85ac945c3f819227
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Chronic recalcitrant erythema nodosum leprosum (ENL) or type 2 reaction (T2R) is a severe condition found in approximately 50% of multibacillary leprosy subjects. T2R is associated with important morbidities and may lead to several disabilities, not
Externí odkaz:
https://doaj.org/article/5b048dffd6f145869d09b56773c1c1a0
Autor:
Walker N. Oliveira, Andreza S. Dórea, Pedro P. Carneiro, Maurício T. Nascimento, Lucas P. Carvalho, Paulo R. L. Machado, Albert Schriefer, Olívia Bacellar, Edgar M. Carvalho
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Disseminated Leishmaniasis (DL) is an emerging and severe form of Leishmania (Viannia) braziliensis infection defined by the presence of 10 and up to more than 1,000 skin lesions. The mechanisms underlying parasite dissemination remain unknown. Genot
Externí odkaz:
https://doaj.org/article/273ece04941c49208708abd53a47ede8
Autor:
Clara Mônica F. de Lima, Andrea S. Magalhães, Rúbia Costa, Carolina C. Barreto, Paulo R. L. Machado, Edgar M. Carvalho, Marcus M. Lessa, Lucas P. Carvalho
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
BackgroundMucosal leishmaniasis (ML), the most inflammatory form of tegumentary leishmaniasis, is predominantly caused by Leishmania braziliensis. The disease is characterized by the development of lesions, mainly in the nasal mucosa. An exacerbated
Externí odkaz:
https://doaj.org/article/4545aa4fa3934eb79c1cf46576ed31e8
Autor:
Mariana C. Costa, Camilla S. Paixão, Débora L. Viana, Bruno de O. Rocha, Maíra Saldanha, Lícia M. H. da Mota, Paulo R. L. Machado, Carla Pagliari, Maria de Fátima de Oliveira, Sergio Arruda, Edgar M. Carvalho, Lucas P. Carvalho
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Psoriasis is a chronic, inflammatory disease affecting the skin and joints. The pathogenesis of this disease is associated with genetic, environmental and immunological factors, especially unbalanced T cell activation and improper keratinocyte differ
Externí odkaz:
https://doaj.org/article/03bd0fc4fb2f4162b24ffe27361cd8f4
Autor:
Fábio Peixoto, Maurício T. Nascimento, Rúbia Costa, Juliana Silva, Gaby Renard, Luiz Henrique Guimarães, Gerson Penna, Manoel Barral-Netto, Lucas P. Carvalho, Paulo R. L. Machado, Edgar M. Carvalho
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Cutaneous leishmaniasis (CL) due to L. braziliensis is associated with an exaggerated inflammatory response and tissue damage. Miltefosine is more effective than pentavalent antimony (Sbv) in the treatment of CL, and here, we evaluate the ability of
Externí odkaz:
https://doaj.org/article/1feab120833a4b5daa91f61f171185da
Autor:
Ludmila P. Polari, Pedro Paulo Carneiro, Michael Macedo, Paulo R. L. Machado, Phillip Scott, Edgar M. Carvalho, Olívia Bacellar
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Cutaneous leishmaniasis (CL) caused by infection with Leishmania braziliensis is characterized by an exaggerated inflammatory response that controls the parasite burden, but also contributes to pathology. While myeloid cells are required to eliminate
Externí odkaz:
https://doaj.org/article/6b1d7cae9093420aa9406205153908a0
Autor:
Rosana Sousa, Viviane M. Andrade, Thomas Bair, Nicholas A. Ettinger, Luana Guimarães, Laura Andrade, Luiz H. Guimarães, Paulo R. L. Machado, Edgar M. Carvalho, Mary E. Wilson, Albert Schriefer
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Leishmania braziliensis is an intracellular parasite that resides mostly in macrophages. Both the parasite genome and the clinical disease manifestations show considerable polymorphism. Clinical syndromes caused by L. braziliensis include localized c
Externí odkaz:
https://doaj.org/article/9e487c1ea0e047a9b9755eb451a1b101
Publikováno v:
Anais Brasileiros de Dermatologia, Vol 79, Iss 6, Pp 647-662 (2004)
O conhecimento dos principais mecanismos de defesa imune contra os diversos agentes infecciosos permite a compreensão da patogênese das doenças infectoparasitárias e das várias estratégias do hospedeiro e do parasita. O sistema imunológico atu
Externí odkaz:
https://doaj.org/article/b5e4cb5ec3064181a893331682e7bcba