Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Paulo R L Machado"'
Autor:
Maria Del Mar Castro, Joelle Rode, Paulo R L Machado, Alejandro Llanos-Cuentas, Marcia Hueb, Gláucia Cota, Isis Valentina Rojas, Yenifer Orobio, Oscar Oviedo Sarmiento, Ernesto Rojas, Juliana Quintero, Maria Inês Fernandes Pimentel, Jaime Soto, Carvel Suprien, Fiorela Alvarez, Ana Pilar Ramos, Rayssa Basílio Dos Santos Arantes, Rosiana Estéfane da Silva, Claudia Marcela Arenas, Ivan Darío Vélez, Marcelo Rosandiski Lyra, Nancy Gore Saravia, Byron Arana, Neal Alexander
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 1, p e0011029 (2023)
BackgroundTreatment guidance for children and older adult patients affected by cutaneous leishmaniasis (CL) is unclear due to limited representation of these groups in clinical trials.MethodsWe conducted a collaborative retrospective study to describ
Externí odkaz:
https://doaj.org/article/02a878a290dc45fb8bbfcef2c402dcf8
Autor:
Jacob M Bezemer, Kevin Meesters, Cristhian L Naveda, Paulo R L Machado, Manuel Calvopiña, Mariska M G Leeflang, Henk D F H Schallig, Henry J C de Vries
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 8, p e0010621 (2022)
BackgroundMucosal Leishmaniasis (ML), a neglected tropical disease caused by Leishmania parasites, impairs the quality of life of under-resourced populations in South America. If not treated promptly, this disease progresses to facial deformities and
Externí odkaz:
https://doaj.org/article/ac266226ff8c423daafaca198191a6ed
Autor:
Paulo R L Machado, Lídia M Machado, Mayume Shibuya, Jamile Rego, Warren D Johnson, Marshall J Glesby
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 8, p e0003865 (2015)
BACKGROUND:The role of the host immunity in determining leprosy clinical forms and complications is well recognized, implying that changes in the immune status may interfere with several aspects of the disease. Therefore, we hypothesized that the pre
Externí odkaz:
https://doaj.org/article/ecc1a1518ef141ee9add5d53dece3158
Improved Treatment Outcome Following the Use of a Wound Dressings in Cutaneous Leishmaniasis Lesions
Autor:
Pedro B. Borba, Jamile Lago, Tainã Lago, Mariana Araújo-Pereira, Artur T. L. Queiroz, Hernane S. Barud, Lucas P. Carvalho, Paulo R. L. Machado, Edgar M. Carvalho, Camila I. de Oliveira
Publikováno v:
Pathogens, Vol 13, Iss 5, p 416 (2024)
Leishmaniasis, caused by Leishmania parasites, is a neglected tropical disease and Cutaneous Leishmaniasis (CL) is the most common form. Despite the associated toxicity and adverse effects, Meglumine antimoniate (MA) remains the first-choice treatmen
Externí odkaz:
https://doaj.org/article/5ae325d1c88b4d71a59bd80e470a47ae
Publikováno v:
Pathogens, Vol 13, Iss 4, p 301 (2024)
Cutaneous leishmaniasis (CL), caused by Leishmania braziliensis, in recent decades has shown decreasing cure rates after treatment with meglumine antimoniate (MA). Granulocyte colony-stimulating factor (G-CSF) is a cytokine associated with epithelial
Externí odkaz:
https://doaj.org/article/512c1caef4604c8f85ac945c3f819227
Autor:
Walker N. Oliveira, Andreza S. Dórea, Pedro P. Carneiro, Maurício T. Nascimento, Lucas P. Carvalho, Paulo R. L. Machado, Albert Schriefer, Olívia Bacellar, Edgar M. Carvalho
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Disseminated Leishmaniasis (DL) is an emerging and severe form ofLeishmania (Viannia) braziliensisinfection defined by the presence of 10 and up to more than 1,000 skin lesions. The mechanisms underlying parasite dissemination remain unknown. Genotyp
Autor:
Clara Mônica F. de Lima, Andrea S. Magalhães, Rúbia Costa, Carolina C. Barreto, Paulo R. L. Machado, Edgar M. Carvalho, Marcus M. Lessa, Lucas P. Carvalho
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
BackgroundMucosal leishmaniasis (ML), the most inflammatory form of tegumentary leishmaniasis, is predominantly caused by Leishmania braziliensis. The disease is characterized by the development of lesions, mainly in the nasal mucosa. An exacerbated
Autor:
Clara Mônica F, de Lima, Andrea S, Magalhães, Rúbia, Costa, Carolina C, Barreto, Paulo R L, Machado, Edgar M, Carvalho, Marcus M, Lessa, Lucas P, Carvalho
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Background Mucosal leishmaniasis (ML), the most inflammatory form of tegumentary leishmaniasis, is predominantly caused by Leishmania braziliensis. The disease is characterized by the development of lesions, mainly in the nasal mucosa. An exacerbated
Autor:
Mariana C. Costa, Camilla S. Paixão, Débora L. Viana, Bruno de O. Rocha, Maíra Saldanha, Lícia M. H. da Mota, Paulo R. L. Machado, Carla Pagliari, Maria de Fátima de Oliveira, Sergio Arruda, Edgar M. Carvalho, Lucas P. Carvalho
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Psoriasis is a chronic, inflammatory disease affecting the skin and joints. The pathogenesis of this disease is associated with genetic, environmental and immunological factors, especially unbalanced T cell activation and improper keratinocyte differ
Autor:
Rosana Sousa, Viviane M. Andrade, Thomas Bair, Nicholas A. Ettinger, Luana Guimarães, Laura Andrade, Luiz H. Guimarães, Paulo R. L. Machado, Edgar M. Carvalho, Mary E. Wilson, Albert Schriefer
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Leishmania braziliensis is an intracellular parasite that resides mostly in macrophages. Both the parasite genome and the clinical disease manifestations show considerable polymorphism. Clinical syndromes caused by L. braziliensis include localized c