Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation in mouse embryonic stem cells.

Autor: Oriol Bover, Tiago Justo, Paulo N G Pereira, João Facucho-Oliveira, José M Inácio, José S Ramalho, Ibrahim J Domian, José António Belo

Publikováno v: PLoS ONE, Vol 13, Iss 10, p e0205108 (2018)

Understanding the molecular pathways regulating cardiogenesis is crucial for the early diagnosis of heart diseases and improvement of cardiovascular disease. During normal mammalian cardiac development, collagen and calcium-binding EGF domain-1 (Ccbe

Externí odkaz: https://doaj.org/article/7aab819ab4e047cba1c1000f23e5bace

Naive and Stem Cell Memory T Cell Subset Recovery Reveals Opposing Reconstitution Patterns in CD4 and CD8 T Cells in Chronic Graft vs. Host Disease

Autor: Maria V. Soares, Rita I. Azevedo, Inês A. Ferreira, Sara Bucar, Ana C. Ribeiro, Ana Vieira, Paulo N. G. Pereira, Ruy M. Ribeiro, Dario Ligeiro, Ana C. Alho, António S. Soares, Nádia Camacho, Carlos Martins, Fernanda Lourenço, Raul Moreno, Jerome Ritz, João F. Lacerda

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)

Copyright © 2019 Soares, Azevedo, Ferreira, Bucar, Ribeiro, Vieira, Pereira, Ribeiro, Ligeiro, Alho, Soares, Camacho, Martins, Lourenço, Moreno, Ritz and Lacerda. This is an open-access article distributed under the terms of the Creative Commons At

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c65f3063ad9b95acb5c63eb80c0f470
https://doi.org/10.3389/fimmu.2019.00334

Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling

Autor: Nathan Criem, Agata Stryjewska, Marina Naval Sanchez, Ljuba C. Ponomarev, Susana M. Chuva de Sousa Lopes, Mariya P. Dobreva, Danny Huylebroeck, Kirstie A. Lawson, An Zwijsen, Stein Aerts, Vanesa Abon Escalona, Paulo N. G. Pereira

Publikováno v: Development, 145(13)

Upon gastrulation, the mammalian conceptus transforms rapidly from a simple bilayer into a multilayered embryo enveloped by its extra-embryonic membranes. Impaired development of the amnion, the innermost membrane, causes major malformations. To clar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50811a6c003ad0129c85e18ec146818
https://dev.biologists.org/content/145/13/dev157222.long

Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

Autor: An Zwijsen, Annick Francis, Danny Huylebroeck, Karen Beets, Elizabeth J. Robertson, Paulo N. G. Pereira, Elke Maas, Christine L. Mummery, Iván M. Moya, Ward Sents, Lieve Umans

Publikováno v: Developmental Cell, 22(3), 501-514

Gradients of vascular endothelial growth factor (VEGF) induce single endothelial cells to become leading tip cells of emerging angiogenic sprouts. Tip cells then suppress tip-cell features in adjacent stalk cells via Dll4/Notch-mediated lateral inhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b68db55fbd17ca02b50878eebacaa3

On the origin of amniotic stem cells: of mice and men

Autor: Mariya P. Dobreva, An Zwijsen, Paulo N. G. Pereira, Jan Deprest

Publikováno v: The International Journal of Developmental Biology. 54:761-777

A common characteristic of mammals is the development of extraembryonic supporting tissues and organs that are required for embryonic implantation, survival and development in utero. The amnion is the innermost extraembryonic membrane that eventually

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c188b738dec868c0e047dd6fac3d7500
https://doi.org/10.1387/ijdb.092935md