Toward New Therapeutics for Visceral Leishmaniasis: Efficacy and Mechanism of Action of Amides Inspired by Gibbilimbol B.

Autor: Baltazar FN; Pathophysiology Laboratory, Instituto Butantan, Av. Vital Brazil, 1500, 05503-900 São Paulo, São Paulo, Brazil., Amaral M; Pathophysiology Laboratory, Instituto Butantan, Av. Vital Brazil, 1500, 05503-900 São Paulo, São Paulo, Brazil., Romanelli MM; Pathophysiology Laboratory, Instituto Butantan, Av. Vital Brazil, 1500, 05503-900 São Paulo, São Paulo, Brazil., de Castro Levatti EV; Pathophysiology Laboratory, Instituto Butantan, Av. Vital Brazil, 1500, 05503-900 São Paulo, São Paulo, Brazil., Ramos FF; Pathophysiology Laboratory, Instituto Butantan, Av. Vital Brazil, 1500, 05503-900 São Paulo, São Paulo, Brazil.; Department of Pharmaceutical Sciences, Federal University of São Paulo, Rua São Nicolau, 210, 09913030 Diadema, São Paulo, Brazil., Paulo Melchior de Oliveira Leão L; Institute of Chemistry, Federal University of Alfenas (UNIFAL), R. Gabriel Monteiro da Silva, 700, 37130-000 Alfenas, Minas Gerais, Brazil., Chagas-Paula DA; Institute of Chemistry, Federal University of Alfenas (UNIFAL), R. Gabriel Monteiro da Silva, 700, 37130-000 Alfenas, Minas Gerais, Brazil., Soares MG; Institute of Chemistry, Federal University of Alfenas (UNIFAL), R. Gabriel Monteiro da Silva, 700, 37130-000 Alfenas, Minas Gerais, Brazil., Dias DF; Institute of Chemistry, Federal University of Alfenas (UNIFAL), R. Gabriel Monteiro da Silva, 700, 37130-000 Alfenas, Minas Gerais, Brazil., Aranha CMSQ; Department of Medicine, Federal University of São Paulo (UNIFESP), Av. Dr. Arnaldo, 455, 01246-903 São Paulo, São Paulo, Brazil., Dos Santos Fernandes JP; Department of Pharmaceutical Sciences, Federal University of São Paulo, Rua São Nicolau, 210, 09913030 Diadema, São Paulo, Brazil., Lago JHG; Centre of Natural Sciences and Humanities, Universidade Federal do ABC, Av. dos Estados, 5001, 09210-580 Santo André, São Paulo, Brazil., Tempone AG; Pathophysiology Laboratory, Instituto Butantan, Av. Vital Brazil, 1500, 05503-900 São Paulo, São Paulo, Brazil.

Publikováno v: ACS omega [ACS Omega] 2024 Oct 08; Vol. 9 (44), pp. 44385-44395. Date of Electronic Publication: 2024 Oct 08 (Print Publication: 2024).