Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Paulo J C, Lin"'
Autor:
Hsuan-Yuan Wang, Leike Li, Cody S. Nelson, Richard Barfield, Sarah Valencia, Cliburn Chan, Hiromi Muramatsu, Paulo J. C. Lin, Norbert Pardi, Zhiqiang An, Drew Weissman, Sallie R. Permar
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Human cytomegalovirus (HCMV) remains the most common congenital infection and infectious complication in immunocompromised patients. The most successful HCMV vaccine to date, an HCMV glycoprotein B (gB) subunit vaccine adjuvanted with MF59,
Externí odkaz:
https://doaj.org/article/585f42ecc487449fb50c16c8c227987f
A Pvs25 mRNA vaccine induces complete and durable transmission-blocking immunity to Plasmodium vivax
Autor:
Nawapol Kunkeaw, Wang Nguitragool, Eizo Takashima, Niwat Kangwanrangsan, Hiromi Muramatsu, Mayumi Tachibana, Tomoko Ishino, Paulo J. C. Lin, Ying K. Tam, Sathit Pichyangkul, Takafumi Tsuboi, Norbert Pardi, Jetsumon Sattabongkot
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Plasmodium vivax (P. vivax) is the major malaria parasite outside of Africa and no vaccine is available against it. A vaccine that interrupts parasite transmission (transmission-blocking vaccine, TBV) is considered highly desirable to reduce
Externí odkaz:
https://doaj.org/article/6bd36135820a49e28ce8dba3dfe11f1d
Autor:
Jennifer Connors, David Joyner, Nathan J. Mege, Gina M. Cusimano, Matthew R. Bell, Jennifer Marcy, Bhavani Taramangalam, Kenneth M. Kim, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, Michele A. Kutzler, Mohamad-Gabriel Alameh, Elias K. Haddad
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
The role of empty lipid nanoparticles in eliciting dendritic cell maturation and innate immune signaling is shown to be impaired in older adults, potentially contributing to lower immune responses to SARS-CoV-2 mRNA-based vaccines.
Externí odkaz:
https://doaj.org/article/f939a91eb95f4c4fb669b5245aa1ee19
Autor:
Clifford T. H. Hayashi, Yi Cao, Leor C. Clark, Abhai K. Tripathi, Fidel Zavala, Garima Dwivedi, James Knox, Mohamad-Gabriel Alameh, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, Nirbhay Kumar
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Malaria is a deadly disease responsible for between 550,000 and 627,000 deaths annually. There is a pressing need to develop vaccines focused on malaria elimination. The complex lifecycle of Plasmodium falciparum provides opportunities not o
Externí odkaz:
https://doaj.org/article/5ee49b242f0f42e2a68eb0e937a5e7d5
Autor:
Nawapol Kunkeaw, Wang Nguitragool, Eizo Takashima, Niwat Kangwanrangsan, Hiromi Muramatsu, Mayumi Tachibana, Tomoko Ishino, Paulo J. C. Lin, Ying K. Tam, Sathit Pichyangkul, Takafumi Tsuboi, Norbert Pardi, Jetsumon Sattabongkot
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/6021f933132340f7af4cc14704f35b9e
Autor:
Brandon Carter, Pinghan Huang, Ge Liu, Yuejin Liang, Paulo J. C. Lin, Bi-Hung Peng, Lindsay G. A. McKay, Alexander Dimitrakakis, Jason Hsu, Vivian Tat, Panatda Saenkham-Huntsinger, Jinjin Chen, Clarety Kaseke, Gaurav D. Gaiha, Qiaobing Xu, Anthony Griffiths, Ying K. Tam, Chien-Te K. Tseng, David K. Gifford
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Licensed COVID-19 vaccines ameliorate viral infection by inducing production of neutralizing antibodies that bind the SARS-CoV-2 Spike protein and inhibit viral cellular entry. However, the clinical effectiveness of these vaccines is transitory as vi
Externí odkaz:
https://doaj.org/article/37d4703fe4c94f879a346594ee70e087
Autor:
Ishita N. Waghela, Katherine L. Mallory, Justin A. Taylor, Cosette G. Schneider, Tatyana Savransky, Chris J. Janse, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, Evelina Angov
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The secreted malarial protein, Cell-Traversal protein for Ookinetes and Sporozoites (CelTOS), is highly conserved among Plasmodium species, and plays a role in the invasion of mosquito midgut cells and hepatocytes in the vertebrate host. CelTOS was i
Externí odkaz:
https://doaj.org/article/288fe199656c4f45939cd999d667f874
Autor:
Sandra Nakandakari-Higa, Roham Parsa, Bernardo S. Reis, Renan V. H. de Carvalho, Luka Mesin, Hans-Heinrich Hoffmann, Juliana Bortolatto, Hiromi Muramatsu, Paulo. J. C. Lin, Angelina M. Bilate, Charles M. Rice, Norbert Pardi, Daniel Mucida, Gabriel D. Victora, Maria Cecilia C. Canesso
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Efficient mouse models to study SARS-CoV-2 infection are critical for the development and assessment of vaccines and therapeutic approaches to mitigate the current pandemic and prevent reemergence of COVID-19. While the first generation of mouse mode
Externí odkaz:
https://doaj.org/article/03a40c2ab38f4b908a732a3ff73ed920
Autor:
Clifford T. H. Hayashi, Yi Cao, Leor C. Clark, Abhai K. Tripathi, Fidel Zavala, Garima Dwivedi, James Knox, Mohamad-Gabriel Alameh, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, Nirbhay Kumar
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/567bf426669a49e5821095f8e4be4774
Autor:
Chutamath Sittplangkoon, Mohamad-Gabriel Alameh, Drew Weissman, Paulo J. C. Lin, Ying K. Tam, Eakachai Prompetchara, Tanapat Palaga
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
An mRNA with unmodified nucleosides induces type I interferons (IFN-I) through the stimulation of innate immune sensors. Whether IFN-I induced by mRNA vaccine is crucial for anti-tumor immune response remains to be elucidated. In this study, we inves
Externí odkaz:
https://doaj.org/article/d82af9ac297f4c658fd7c70b4472e301