Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Paulo F. Severino"'
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Akademický článek
Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cells expressing sialyltransferase ST3GAL1
Autor: Paulo F. Severino, Mariana Silva, Mylene Carrascal, Nadia Malagolini, Mariella Chiricolo, Giulia Venturi, Roberto Barbaro Forleo, Annalisa Astolfi, Mariangela Catera, Paula A. Videira, Fabio Dall’Olio
Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Treatment with Bacillus Calmette-Guérin (BCG) is the gold standard adjuvant immunotherapy of non-muscle invasive bladder cancer (NMIBC), although it fails in one third of the patients. NMIBC expresses two tumor-associated O-linke
Externí odkaz: https://doaj.org/article/e07213fafe4648a8806488025e38a525
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2
NOA method – three dimensions in the governance of kidney transplantation: Need-Opportunity-Accessibility, how to engage them?
Autor: Paulo F. Severino, Carlos Brás-Geraldes, Ana Luísa Papoila, Ana Franca, Vanda Rute Patrício Palmeiro, Ana Paula Fernandes, Alexandrina Dos Santos, Catarina Bolotinha
Publikováno v: MethodsX
MethodsX, Vol 8, Iss, Pp 101542-(2021)
Background Despite all efforts, the demand for organs increases. New and better strategies are still needed, critical in a crisis like pandemics. Methodology A mathematical approach that integrates need, Opportunity, and Accessibility to kidney trans
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19057474def8fecfb12b1ff4e501c3b7
http://europepmc.org/articles/PMC8563650
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3
Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cells expressing sialyltransferase ST3GAL1
Autor: Annalisa Astolfi, Mariangela Catera, Mariella Chiricolo, Paulo F. Severino, Mariana Silva, Paula A. Videira, Giulia Venturi, Roberto Barbaro Forleo, Fabio Dall'Olio, Mylène A. Carrascal, Nadia Malagolini
Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
BMC Cancer
This work was supported by: Portuguese Foundation for Science and Technology (FCT) PhD grants SFRH/BD/45120/2008 (Paulo F. Severino), SFRH/BD/81860/2011 (Mariana Silva) and SFRH/BD/100970/2014 (Mylene Carrascal), Liga Portuguesa Contra o Cancro 2011
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567ce5877a3ebe75afeb5b915bf921e7
http://hdl.handle.net/11392/2411097
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4
Expression of sialyl-Tn sugar antigen in bladder cancer cells affects response to Bacillus Calmette Guérin (BCG) and to oxidative damage
Autor: Mariangela Catera, Paulo F. Severino, Fabio Dall'Olio, Nadia Malagolini, Annalisa Astolfi, Mariana Silva, Giulia Venturi, Mariella Chiricolo, Paula A. Videira, Mylène A. Carrascal
// Paulo F. Severino 1, 3, * , Mariana Silva 1, * , Mylene Carrascal 1 , Nadia Malagolini 3 , Mariella Chiricolo 3 , Giulia Venturi 3 , Annalisa Astolfi 4 , Mariangela Catera 3 , Paula A. Videira 1, 2 and Fabio Dall’Olio 3 1 Centro de Estudos de Do
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d325dc4af9acf1d5fef2d7e92834a254
http://hdl.handle.net/11392/2411111
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5
Response of high-risk of recurrence/progression bladder tumours expressing sialyl-Tn and sialyl-6-T to BCG immunotherapy
Autor: Elisabete Fernandes, Lúcio Lara Santos, Paulo F. Severino, Luís Lima, Fabio Dall'Olio, Teresina Amaro, Ana P. M. Tavares, Celso A. Reis, Ricardo Cruz, Paula A. Videira, José Alexandre Ferreira, Mariana Silva, Andreia Miranda, Francisco Amado, Sofia A. Pereira
Publikováno v: British Journal of Cancer
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Background: High risk of recurrence/progression bladder tumours is treated with Bacillus Calmette-Gue´ rin (BCG) immunotherapy after complete resection of the tumour. Approximately 75% of these tumours express the uncommon carbohydrate antigen sialy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9c63cec04368990c598ee972b91971
http://europepmc.org/articles/PMC3798967
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6
Expression of sialyl-Tn sugar antigen in bladder cancer cells affects response to
Autor: Paulo F, Severino, Mariana, Silva, Mylene, Carrascal, Nadia, Malagolini, Mariella, Chiricolo, Giulia, Venturi, Annalisa, Astolfi, Mariangela, Catera, Paula A, Videira, Fabio, Dall'Olio
Publikováno v: Oncotarget
The sialyl-Tn (sTn) antigen is an O-linked carbohydrate chain aberrantly expressed in bladder cancer (BC), whose biosynthesis is mainly controlled by the sialyltransferase ST6GALNAC1. Treatment with Bacillus Calmette-Guérin (BCG) is the most effecti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::624af92b0ed83d72b2253a7e07f5ce7b
https://pubmed.ncbi.nlm.nih.gov/28903359
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7
Sialyl Tn-expressing bladder cancer cells induce a tolerogenic phenotype in innate and adaptive immune cells
Autor: Cláudia Pen, Hermínia Quinto, Fabio Dall'Olio, Lúcio Lara Santos, Mariana Silva, Paula A. Videira, Paulo F. Severino, M. Guadalupe Cabral, Mylène A. Carrascal, Fernando M. Calais, José Alexandre Ferreira, Dário Ligeiro
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
This work was supported by the Portuguese Foundation for Science and Technology (FCT) - PTDC/SAU-MII/67561/2006 and Premio Santander Totta - UNL (Paula A. Videira), LPCC/Pfizer2011 (Mylene A. Carrascal), SFRH/BPD/21619/2005 (M. Guadalupe Cabral), SFR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27baecbce43e4d8a8e571e306cb7d7a1
http://www.scopus.com/inward/record.url?scp=84899482681&partnerID=8YFLogxK
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8
Overexpression of tumour-associated carbohydrate antigen sialyl-Tn in advanced bladder tumours
Autor: Maria José Oliveira, Sofia A. Pereira, Fabio Dall'Olio, Paulo F. Severino, Luís Lima, Francisco Amado, Rui Vitorino, Céu Costa, Mylène A. Carrascal, Mariana Silva, José Alexandre Ferreira, Teresina Amaro, Andreia Almeida, Paula A. Videira, Celso A. Reis, Elisabete Fernandes, Lúcio Lara Santos
Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
This work was supported by Portuguese Foundation for Science and Technology (FCT) Postdoctoral grant SFRH/BPD/66288/2009 (Jose Alexandre Ferreira), PhD grant SFRH/BD/43399/2008 (Luis Lima), SFRH/BD/81860/2011 (Mariana Silva), SFRH/BD/45120/2008 (Paul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a819f9118b927a0a7900c566f55f3e45
http://www.scopus.com/inward/record.url?scp=84878107131&partnerID=8YFLogxK
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9
Synthesis and evaluation of N-acylamino acids derivatives of triazenes. Activation by tyrosinase in human melanoma cell lines
Autor: Guadalupe Cabral, Paulo F. Severino, Paula A. Videira, Ana Paula Francisco, Joana Almeida, Eduarda Mendes, M. Jesus Perry, Ana Monteiro, João D. Pereira, Rafael Nunes, Ana E. Sousa
Publikováno v: European journal of medicinal chemistry. 70
In this research work we report the synthesis of a new series of triazene prodrugs designed for Melanocyte-Directed Enzyme Prodrug Therapy (MDEPT). These compounds are derived from the N-acyltyrosine amino acid - a good enzyme substrate for the tyros
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1aa9c89017e186b239e5475892f094d
https://pubmed.ncbi.nlm.nih.gov/24125877
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10
Bladder cancer–glycosylation insights
Autor: Paulo F. Severino, Mylène A. Carrascal, Paula A. Videira, Mariana Silva, Fabio Dall'Olio, Fernando M. Calais
Bladder cancer is a common urologic cancer in Europe, with the highest recurrence rate of any malignancy. Early diagnosis and correct staging of the disease is critical, not only for planning treatment but also for selecting follow-up schedules, due
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81efc15b96f9fb4955be663c09a27da
http://hdl.handle.net/11585/128702
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