Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Paulo Czarnewski"'
Autor:
Egle Kvedaraite, Magda Lourda, Natalia Mouratidou, Tim Düking, Avinash Padhi, Kirsten Moll, Paulo Czarnewski, Indranil Sinha, Ioanna Xagoraris, Efthymia Kokkinou, Anastasios Damdimopoulos, Whitney Weigel, Olga Hartwig, Telma E. Santos, Tea Soini, Aline Van Acker, Nelly Rahkonen, Malin Flodström Tullberg, Emma Ringqvist, Marcus Buggert, Carl Jorns, Ulrik Lindforss, Caroline Nordenvall, Christopher T. Stamper, David Unnersjö-Jess, Mira Akber, Ruta Nadisauskaite, Jessica Jansson, Niels Vandamme, Chiara Sorini, Marijke Elise Grundeken, Helena Rolandsdotter, George Rassidakis, Eduardo J. Villablanca, Maja Ideström, Stefan Eulitz, Henrik Arnell, Jenny Mjösberg, Jan-Inge Henter, Mattias Svensson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Stromal cells support epithelial cell and immune cell homeostasis and play an important role in inflammatory bowel disease (IBD) pathogenesis. Here, we quantify the stromal response to inflammation in pediatric IBD and reveal subset-specific
Externí odkaz:
https://doaj.org/article/4dc18c7a87ab47da922abb5a03ceaf68
Autor:
Meng Yu, Afandi Charles, Alberto Cagigi, Wanda Christ, Björn Österberg, Sara Falck-Jones, Lida Azizmohammadi, Eric Åhlberg, Ryan Falck-Jones, Julia Svensson, Mu Nie, Anna Warnqvist, Fredrika Hellgren, Klara Lenart, Rodrigo Arcoverde Cerveira, Sebastian Ols, Gustaf Lindgren, Ang Lin, Holden Maecker, Max Bell, Niclas Johansson, Jan Albert, Christopher Sundling, Paulo Czarnewski, Jonas Klingström, Anna Färnert, Karin Loré, Anna Smed-Sörensen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Effective humoral immune responses require well-orchestrated B and T follicular helper (Tfh) cell interactions. Whether these interactions are impaired and associated with COVID-19 disease severity is unclear. Here, longitudinal blood sample
Externí odkaz:
https://doaj.org/article/5d37811980464becbf0604481a523bb4
Autor:
Gabriella Edfeldt, Vilde Kaldhusdal, Paulo Czarnewski, Frideborg Bradley, Sofia Bergström, Julie Lajoie, Jiawu Xu, Anna Månberg, Joshua Kimani, Julius Oyugi, Peter Nilsson, Annelie Tjernlund, Keith R. Fowke, Douglas S. Kwon, Kristina Broliden
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-22 (2023)
Abstract Background The majority of studies characterizing female genital tract microbiota have focused on luminal organisms, while the presence and impact of tissue-adherent ectocervical microbiota remain incompletely understood. Studies of luminal
Externí odkaz:
https://doaj.org/article/dff8081e1741453d9de5744b71287711
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Venous thromboembolism (VTE) is a leading cause of preventable deaths in hospitals, and its incidence is not decreasing despite extensive efforts in clinical and laboratory research. Venous thrombi are primarily formed in the valve pockets of deep ve
Externí odkaz:
https://doaj.org/article/762a9bb2fa2d401fbd3dd6ef392e402e
Autor:
Frideborg Bradley, Mathias Franzén Boger, Vilde Kaldhusdal, Alexandra Åhlberg, Gabriella Edfeldt, Julie Lajoie, Sofia Bergström, Kenneth Omollo, Anastasios Damdimopoulos, Paulo Czarnewski, Anna Månberg, Julius Oyugi, Joshua Kimani, Peter Nilsson, Keith Fowke, Annelie Tjernlund, Kristina Broliden
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010494 (2022)
Depot medroxyprogesterone acetate (DMPA) is an injectable hormonal contraceptive used by millions of women worldwide. However, experimental studies have associated DMPA use with genital epithelial barrier disruption and mucosal influx of human immuno
Externí odkaz:
https://doaj.org/article/b75ef1229c0244689feca2bb38e81604
Autor:
Rosanne E. Veerman, Loes Teeuwen, Paulo Czarnewski, Gözde Güclüler Akpinar, AnnSofi Sandberg, Xiaofang Cao, Maria Pernemalm, Lukas M. Orre, Susanne Gabrielsson, Maria Eldh
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 9, Pp n/a-n/a (2021)
Abstract Extracellular vesicles (EVs) are increasingly tested as therapeutic vehicles and biomarkers, but still EV subtypes are not fully characterised. To isolate EVs with few co‐isolated entities, a combination of methods is needed. However, this
Externí odkaz:
https://doaj.org/article/288f51556f364ffeab621ae94079f212
Autor:
Paulo Czarnewski, Sara M. Parigi, Chiara Sorini, Oscar E. Diaz, Srustidhar Das, Nicola Gagliani, Eduardo J. Villablanca
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Clinical and molecular heterogeneity of ulcerative colitis presents unresolved challenges to identify predictive biomarkers of response to therapies. Here, the authors combine mouse colitis time course with patient biopsy transcriptomes, achieving un
Externí odkaz:
https://doaj.org/article/d46d311b84244bbf8766ebda31a8df22
Autor:
Leonie Brockmann, Shiwa Soukou, Babett Steglich, Paulo Czarnewski, Lilan Zhao, Sandra Wende, Tanja Bedke, Can Ergen, Carolin Manthey, Theodora Agalioti, Maria Geffken, Oliver Seiz, Sara M. Parigi, Chiara Sorini, Jens Geginat, Keishi Fujio, Thomas Jacobs, Thomas Roesch, Jacob R. Izbicki, Ansgar W. Lohse, Richard A. Flavell, Christian Krebs, Jan-Ake Gustafsson, Per Antonson, Maria Grazia Roncarolo, Eduardo J. Villablanca, Nicola Gagliani, Samuel Huber
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Tr1 cells are considered an immunosuppressive CD4 T cell population producing IL-10. Here the authors show that IL-10 is insufficient for Tr1 immunosuppression, define surface markers and transcriptional program of the immunosuppressive subset within
Externí odkaz:
https://doaj.org/article/9965d7bfb0694a05899ad6316109497d
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Toxoplasma gondii is known to cause congenital infection in humans and animals and severe disease in immunocompromised individuals; consequently development of vaccines against the parasite is highly necessary. Under stress conditions, T. gondii expr
Externí odkaz:
https://doaj.org/article/056f631755c042448da5a65186caa36f
Publikováno v:
Nutrients, Vol 9, Iss 1, p 68 (2017)
Vitamin A (VA) is amongst the most well characterized food-derived nutrients with diverse immune modulatory roles. Deficiency in dietary VA has not only been associated with immune dysfunctions in the gut, but also with several systemic immune disord
Externí odkaz:
https://doaj.org/article/4d5ad540c5804abfbcb78084e918cdee