CDC25B Inhibition by Menadione: A Potential New Therapeutical Approach

Autor: Carla de Castro Sant’ Anna, Helem Ferreira Ribeiro, Valdenira de Jesus Oliveira Kato, Rafael Maia de Sousa Brasil, Amanda Braga Bona, Danielle Feio da Costa, Isamu Komatsu Lima, Paulo Cardoso Soares, Ana Paula Araújo Guimarães, Paulo Pimentel de Assumpção, Rommel Rodriguez Burbano

Publikováno v: Anti-Cancer Agents in Medicinal Chemistry. 22:2927-2932

Abstract: Gastric cancer (GC) is the fifth most common type of tumor and the third leading cause of cancer death worldwide. The evolution of gastric carcinogenesis is still poorly understood and, for this reason, preclinical research protocols were e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7d9ba9edde2bce693a13c2be1ded534
https://doi.org/10.2174/1871520622666220418131935

New prognostic markers revealed by RNA-Seq transcriptome analysis after MYC silencing in a metastatic gastric cancer cell line

Autor: Juan A. Rey, Jersey Heitor da Silva Maués, Hygor Ferreira-Fernandes, Alcemir Rodrigues Santos, Paulo Cardoso Soares, Giovanny R. Pinto, Rommel Mario Rodriguez Burbano, Severino Cavalcante de Sousa Júnior, Luana de Oliveira Lopes, Helem Ferreira Ribeiro

Publikováno v: Oncotarget

MYC overexpression is considered a driver event in gastric cancer (GC), and is frequently correlated with poor prognosis and metastasis. In this study, we evaluated the prognostic value of genes upregulated by MYC in patients with GC. Metastatic GC c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e38928552b4932a1f1dcfec518dbdf1
https://doi.org/10.18632/oncotarget.27208

PD-L1 expression associated with Epstein-Barr virus status and patients survival in a large cohort of gastric cancer patients in northern Brazil

Autor: Jersey Heitor da Silva Maués, Rommel Mario Rodriguez Burbano, Paulo Pimentel Assumpção, Igor Brasil Costa, Paulo Cardoso Soares, Claúdia Nazaré de Souza Almeida Titan Martins, Caroline de Fátima Aquino Moreira-Nunes, Isamu Komatsu Lima, Leticia Martins Lamarão, Carolina Rosal Teixeira de Souza, Danielle Feio

Publikováno v: Repositório Digital do Instituto Evandro Chagas (Patuá)
Instituto Evandro Chagas (IEC)
instacron:IEC
Cancers, Vol 13, Iss 3107, p 3107 (2021)
Cancers
Volume 13
Issue 13

Gastric cancer (GC) is a worldwide health problem, making it one of the most common types of cancer, in fifth place of all tumor types, and the third highest cause of cancer deaths in the world. There is a subgroup of GC that consists of tumors infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da20bd91508d74d4010161f92e6448a8

HPV positive, wild type TP53, and p16 overexpression correlate with the absence of residual tumors after chemoradiotherapy in anal squamous cell carcinoma

Autor: Paulo Cardoso Soares, Paulo Pimentel Assumpção, Rommel Mario Rodriguez Burbano, Luiz Claudio Santos Thuler, Bruno Moreira Soares, Eliana Abdelhay, Samia Demachki, Gessica Valéria Rocha Ferro, Luis Felipe Ribeiro Pinto, Leticia Martins Lamarão

Publikováno v: BMC Gastroenterology, Vol 18, Iss 1, Pp 1-11 (2018)
BMC Gastroenterology

Background Anal residual tumors are consensually identified within six months of chemoradiotherapy and represent a persistent lesion that may have prognostic value for overall survival. The aim of this study was to evaluate the association of HPV and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e6cde2f973e4d9e812b4136bd6aa70
http://link.springer.com/article/10.1186/s12876-018-0758-2

Frequency of the Loss of Heterozygosity of the NF2 Gene in Sporadic Spinal Schwannomas

Autor: Fabricio Mesquita Tuji, Bárbara do Nascimento Borges, Juan A. Rey, Paulo Cardoso Soares, Rommel Mario Rodriguez Burbano, Giovanny R. Pinto, Alberto Gomes Ferreira Junior, Raimundo Miranda de Carvalho, Luiz Cláudio Lopes Chaves, Carla De Castro Sant' Anna, Eric Homero Albuquerque Paschoal

Publikováno v: Anticancer Research. 38

Background/aim Individuals with type 2 Neurofibromatosis are predisposed for the appearance of schwannomas. In the present study we analyzed the loss of heterozygosity and mutations in the NF2 gene in patients with sporadic Schwannoma without Neurofi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11626e1ce7de003218a15b92ec86f2f0
https://doi.org/10.21873/anticanres.12455