Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Paulo C Almeida"'
Autor:
Wagner A S Judice, Marcella A Manfredi, Gerson P Souza, Thiago M Sansevero, Paulo C Almeida, Cláudio S Shida, Tarsis F Gesteira, Luiz Juliano, Gareth D Westrop, Sanya J Sanderson, Graham H Coombs, Ivarne L S Tersariol
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80153 (2013)
Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their
Externí odkaz:
https://doaj.org/article/0147605441e94b73a97ea1a6f9f4b77a
Autor:
Gabriel L C Nunes, Alyne Simões, Fábio H Dyszy, Claudio S Shida, Maria A Juliano, Luiz Juliano, Tarsis F Gesteira, Helena B Nader, Gillian Murphy, Alain F Chaffotte, Michel E Goldberg, Ivarne L S Tersariol, Paulo C Almeida
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21525 (2011)
Heparin has been shown to regulate human neutrophil elastase (HNE) activity. We have assessed the regulatory effect of heparin on Tissue Inhibitor of Metalloproteases-1 [TIMP-1] hydrolysis by HNE employing the recombinant form of TIMP-1 and correlate
Externí odkaz:
https://doaj.org/article/afc48b67b6e64ee1ad314b993234f385
Autor:
Vitor Oliveira, Cláudio S. Shida, Leandro M. Castro, Alison Colquhoun, Stephen Hyslop, Antonio C.M. Camargo, Claudia C. Rodrigues, Emer S. Ferro, Marc J. Glucksman, James L. Roberts, Maria A. Juliano, Paulo C. Almeida, Paula A.G. Garrido, Luiz Juliano, Valerie Grum-Tokars
Publikováno v:
FEBS Journal. 272:2978-2992
The metalloendopeptidase 24.15 (EP24.15) is ubiquitously present in the extracellular environment as a secreted protein. Outside the cell, this enzyme degrades several neuropeptides containing from 5 to 17 amino acids (e.g. gonadotropin releasing hor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b3e59034abd692137f7f7e21fd296e8
https://doi.org/10.1111/j.1742-4658.2005.04692.x
https://doi.org/10.1111/j.1742-4658.2005.04692.x
Autor:
Jair R. Chagas, Euridice Carmona, Ivarne L.S. Tersariol, Adelaide Faljoni-Alario, Paulo C. Almeida, Luiz Juliano, Iseli L. Nantes, Helena B. Nader, Cca Rizzi
Publikováno v:
Journal of Biological Chemistry. 276:944-951
It has been shown that lysosomal cysteine proteinases, specially cathepsin B, has been implicated in a variety of diseases involving tissue remodeling states, such as inflammation, parasite infection, and tumor metastasis, by degradation of extracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b997d98d4eb97af8fb7ff846e6532cca
https://doi.org/10.1074/jbc.m003820200
https://doi.org/10.1074/jbc.m003820200
Autor:
Vitor Oliveira, Paulo C. Almeida, Maria A. Juliano, Emer S. Ferro, Marcelo D. Gomes, Maria E.M. Oshiro, Luiz Juliano
Publikováno v:
Journal of Cellular Biochemistry. 76:478-488
We combined fluorogenic substrates or internally quenched fluorescent peptides with specific inhibitors in the pH profile of proteolytic activity experiments in order to detect proteolytic activities in lysates of MDCK cells. Hydrolytic activities re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c9e5caf11e561052cb95fd15f3ddd5e
https://doi.org/10.1002/(sici)1097-4644(20000301)76:3<478::aid-jcb14>3.0.co
https://doi.org/10.1002/(sici)1097-4644(20000301)76:3<478::aid-jcb14>3.0.co
Autor:
Jair R. Chagas, Wagner Alves de Souza Judice, Paulo C. Almeida, Helena B. Nader, Ivarne L.S. Tersariol, Cca Rizzi, Iseli L. Nantes, Luiz Juliano
Publikováno v:
Journal of Biological Chemistry. 274:30433-30438
Papain is considered to be the archetype of cysteine proteinases. The interaction of heparin and other glycosaminoglycans with papain may be representative of many mammalian cysteine proteinase-glycosaminoglycan interactions that can regulate the fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61ce21388c6baa82d0018b4c772e7910
https://doi.org/10.1074/jbc.274.43.30433
https://doi.org/10.1074/jbc.274.43.30433
Autor:
Alyne Simões, Alain Chaffotte, Luiz Juliano, Tarsis F. Gesteira, Gabriel L. C. Nunes, Cláudio S. Shida, Maria A. Juliano, Helena B. Nader, Paulo C. Almeida, Ivarne L.S. Tersariol, Fabio Henrique Dyszy, Michel Goldberg, Gillian Murphy
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 6, p e21525 (2011)
PLoS ONE, Vol 6, Iss 6, p e21525 (2011)
Heparin has been shown to regulate human neutrophil elastase (HNE) activity. We have assessed the regulatory effect of heparin on Tissue Inhibitor of Metalloproteases-1 [TIMP-1] hydrolysis by HNE employing the recombinant form of TIMP-1 and correlate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7387180bdbb9ec23ef72c5e4cc8df59
http://europepmc.org/articles/PMC3121799
http://europepmc.org/articles/PMC3121799
Autor:
Elizabeth F, Daher, Rafael S A, Lima, Geraldo B, Silva Júnior, João Paulo C, Almeida, Francisco Júlio W S, Siqueira, Silvia Q, Santos, Stephanie W, Silva, Alexandre B, Libório
Publikováno v:
Acta bio-medica : Atenei Parmensis. 79(3)
Rhabdomyolysis is associated with infectious diseases in approximately 5% of cases and acute kidney injury occurs in 33-50% of cases. Gangrenous myositis is a deep seated infection of the subcutaneous and muscular tissues. We report the case of an 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2e4fcfc0c8c4bc68d279d750080c76c
https://pubmed.ncbi.nlm.nih.gov/19260387
https://pubmed.ncbi.nlm.nih.gov/19260387
Autor:
Ivarne L.S. Tersariol, Rodrigo L. O. R. Cunha, Jair R. Chagas, Miriam E. Urano, João V. Comasseto, Claudia Bincoletto, Paulo C. Almeida
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(3)
New organotellurium(IV) compounds with specific cysteine protease inhibitory activity were synthesized. Serine and aspartic protease activity were not affected by any of these compounds. All Te(IV) compounds tested exhibited high specific second-orde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c099ff40f4eba11a7ef983ec9ac365
https://pubmed.ncbi.nlm.nih.gov/15664852
https://pubmed.ncbi.nlm.nih.gov/15664852
Autor:
Alessandra Linardi, Andrea S. Heimann, Fabio C. Gozzo, Stephen Hyslop, José Eduardo Krieger, Cláudio S. Shida, Marcos N. Eberlin, Vanessa Rioli, Emer S. Ferro, Paulo C. Almeida
Publikováno v:
The Journal of biological chemistry. 278(10)
Endopeptidase 24.15 (EC; ep24.15), neurolysin (EC; ep24.16), and angiotensin-converting enzyme (EC; ACE) are metallopeptidases involved in neuropeptide metabolism in vertebrates. Using catalytically inactive forms of ep24.15 and ep24.16, we have iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937ab9580128b4721ad2c13a50758a3d
https://pubmed.ncbi.nlm.nih.gov/12500972
https://pubmed.ncbi.nlm.nih.gov/12500972