Výsledky vyhledávání - "Paulo C, Vieira"

Akademický článek

ALCALOIDES ACRIDÔNICOS INIBEM CATEPSINA L E V

Autor: Emerson F. Marques, Paulo C. Vieira, Richele P. Severino

Publikováno v: Química Nova, Vol 39, Iss 1, Pp 58-62 (2016)

Cathepsins represent a class of enzymes that has the primary function of randomly degrading proteins in the lysosomes, although are also involved in different pathologies. The aim of this paper was to evaluate the capacity of acridone alkaloids isola

Externí odkaz: https://doaj.org/article/e4596ce7703e49a1bb2c8928d1c06b55

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Akademický článek

New Limonoids from Hortia oreadica and Unexpected Coumarin from H. superba Using Chromatography over Cleaning Sephadex with Sodium Hypochlorite

Autor: Vanessa G.P. Severino, Sâmya D.L. de Freitas, Patrícia A.C. Braga, Moacir Rossi Forim, M. Fátima das G.F. da Silva, João B. Fernandes, Paulo C. Vieira, Tiago Venâncio

Publikováno v: Molecules, Vol 19, Iss 8, Pp 12031-12047 (2014)

Previous investigations of H. oreadica reported the presence of a wide spectrum of complex limonoids and dihydrocinnamic acids. Our interest in the Rutaceae motivated a reinvestigation of H. oreadica, H. brasiliana and H. superba searching for other

Externí odkaz: https://doaj.org/article/3a74615b01de4f82a87eae557d92d3b7

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Biotransformation of pungent constituents from ginger (Zingiber officinale Roscoe) by Colletotrichum gloeosporioides yields oxidative ortho–ortho coupling products

Autor: Paulo C. Vieira, Roberta Marques Dias de Ávila, Leonardo Toffano, Maria Fátima das Graças Fernandes da Silva, João B. Fernandes, Lorena R.F. de Sousa

Publikováno v: Biocatalysis and Biotransformation. 40:95-106

This work investigated the biotransformation of ginger constituents (zingerone, [6]-shogaol, [6]-gingerol, and methyl-[6]-gingerol) by the pathogenic fungus Colletotrichum gloeosporioides. Experime...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d26ca086d764c7d78c61beff1509dc5
https://doi.org/10.1080/10242422.2021.1878159

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Insecticidal activity of copper (II) complexes with flavanone derivatives

Autor: Antonio Bernardo, Maria Fátima das Graças Fernandes da Silva, Gracielle Oliveira Sabbag Cunha, Moacir Rossi Forim, João B. Fernandes, Ana Carolina Volante, Andreia Pereira Matos, Paulo C. Vieira, André Lucio Franceschini Sarria

Publikováno v: Natural Product Research. 36:1342-1345

In this work, we describe the insecticidal activity against Spodoptera frugiperda of flavanone derivatives (naringin, naringenin and hesperidin) complexed to copper (II). For the assays, the compounds were incorporated into an artificial diet and off

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fa578eefb50c799744ce3f0df158eb
https://doi.org/10.1080/14786419.2020.1868465

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Inhibitory Activity and Docking Studies of Cathepsin V for Isoflavanoids from Dalbergia miscolobium Benth

Autor: Warley de Souza Borges, Laysa Lannes Pereira Ferreira Moreira, Eder Lana e Silva, Paulo C. Vieira, Rodrigo Rezende Kitagawa, Keyller Bastos Borges, Weverson Cavalcante Cardoso, Pedro Alves Bezerra Morais

Publikováno v: Revista Virtual de Química. 13:136-145

Plant extracts from Dalbergia genus have demonstrated a wide range of biological activities including analgesic, antidiabetic, anti-inflammatory and antimicrobial. In this work, the chemical study of the extracts from the leaves and branches of Dalbe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd547f5284a295d4fa86ce15c2d320ae
https://doi.org/10.21577/1984-6835.20200135

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[10]-Gingerol improves doxorubicin anticancer activity and decreases its side effects in triple negative breast cancer models

Autor: Angélica Elen Graminha, Marina Araújo Naves, Rebeka Tomasin, Liany Luna-Dulcey, Borhane Annabi, Ramon Handerson Gomes Teles, Márcia Regina Cominetti, James Almada da Silva, Paulo C. Vieira, Vinicius Duval da Silva, Ana Carolina Baptista Moreno Martin

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Although doxorubicin is widely used to treat cancer, severe side effects limit its clinical use. Combination of standard chemotherapy with natural products can increase the efficacy and attenuate the side effects of current therapies. Here we studied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dca9bc936a1d234e645bd9161b56cf7
https://doi.org/10.1007/s13402-020-00539-z

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Liquid Fungal Cocultivation as a Strategy to Access Bioactive Metabolites

Autor: Ilana Lopes Baratella da Cunha Camargo, Airton Damasceno Silva, Felipe De Paula Nogueira Cruz, Alessandra Regina Pepe Ambrozin, Taynara L. Silva, Leonardo L. G. Ferreira, Adriano D. Andricopulo, Paulo C. Vieira, Renata Krogh, Ana Flávia S. de Camargo

Publikováno v: Planta Medica, 87 (01/02). pp. 187-195.
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Fungi are a rich source of bioactive compounds. Fungal cocultivation is a method of potentiating chemical interactions and, consequently, increasing bioactive molecule production. In this study, we evaluated the bactericidal, antiprotozoal, and cathe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5fa619d1014e62613c2c5317650639
https://doi.org/10.1055/a-1200-2046

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Mycotoxins from Fusarium proliferatum: new inhibitors of papain-like cysteine proteases

Autor: Lorena R.F. de Sousa, Maria Fátima das Graças Fernandes da Silva, Paulo C. Vieira, João B. Fernandes, Taynara L. Silva, Leonardo Toffano

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Braz J Microbiol

Papain-like cysteine proteases (PLCPs) in plants are essential to prevent phytopathogen invasion. In order to search for cysteine protease inhibitors and to investigate compounds that could be associated to pineapple Fusarium disease, a chemistry inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a54bca69f55a008fe5b26087ddbb4c7
https://doi.org/10.1007/s42770-020-00256-7

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