Pegcetacoplan controls hemolysis in complement inhibitor–naive patients with paroxysmal nocturnal hemoglobinuria

Autor: Raymond Siu Ming Wong, Juan Ramon Navarro-Cabrera, Narcisa Sonia Comia, Yeow Tee Goh, Henry Idrobo, Daolada Kongkabpan, David Gómez-Almaguer, Mohammed Al-Adhami, Temitayo Ajayi, Paulo Alvarenga, Jessica Savage, Pascal Deschatelets, Cedric Francois, Federico Grossi, Teresita Dumagay

Publikováno v: Blood Advances. 7:2468-2478

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease characterized by complement-mediated hemolysis. Pegcetacoplan is the first C3-targeted therapy approved for adults with PNH (United States), adults with PNH with inadequate response or intol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1aef03eed0e45d20bd5d3611131ef8d5
https://doi.org/10.1182/bloodadvances.2022009129

UM OLHAR SOBRE A LEI DE MEDIAÇÃO (LEI Nº 13.140/2015): A RESOLUÇÃO DE CONFLITOS PELA ADMINISTRAÇÃO PÚBLICA

Autor: Pinto, Marcos Paulo Alvarenga

Publikováno v: Meritum, Law Journal of FUMEC University; V. 17, No. 1-January/April 2022
Meritum, Revista de Derecho de la Universidad FUMEC; V. 17, No. 1-Enero/Abril 2022
Meritum, Journal de droit de l'Université FUMEC; V. 17, n° 1-janvier/avril 2022
Meritum, Revista de Direito da Universidade FUMEC; V. 17, Nº 1-janeiro/abril 2022
Meritum (Belo Horizonte. Online)
Universidade FUMEC
instacron:FUMEC

The object of this paper is an descriptive and critical analysis of Chapter II of Statute no. 13.140/2015, a statute that brought to the brazilian legal system not only the principle and regulation of the institute of conflict mediation, but also the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::44e182d89ec5dde84a7b5db7eec6c87e
http://revista.fumec.br/index.php/meritum/article/view/9036

Efficacy and Safety of Pegcetacoplan Treatment in Complement-Inhibitor Naïve Patients with Paroxysmal Nocturnal Hemoglobinuria: Results from the Phase 3 Prince Study

Autor: Paulo Alvarenga, Juan Ramón Benito Navarro, Cedric G. Francois, Temitayo Ajayi, David Gómez-Almaguer, Mohammed Al-Adhami, Pascal Deschatelets, Teresita Dumagay, Narcisa Sonia Cornejo Comia, Yeow Tee Goh, Raymond S.M. Wong, Daolada Kongkabpan, Henry Idrobo, Federico Grossi

Publikováno v: Blood. 138:606-606

Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare and life-threatening disease characterized by hemolysis and thrombosis. Many patients with PNH use C5-inhibitors (i.e., eculizumab/ravulizumab) to control their symptoms. Although C5-inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec95e3df63bf78ddf8ed4228de79eaee
https://doi.org/10.1182/blood-2021-147493

Casas florestais do concelho de Paredes de Coura: património a reabilitar

Autor: Lages, Jorge Paulo Alvarenga

Publikováno v: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP

A presente dissertação aborda o enquadramento das casas e do quartel florestal (acessos, enquadramento, estado de conservação, análise tipológica e sistema construtivo) como património do Estado Novo no concelho de Paredes de Coura. A pesquisa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a4503cbb0633bd406347ebf5904f5e77
https://hdl.handle.net/10400.26/37258

The precedent system in brazilian law and the limitation of judicial discretion

Autor: Tereza Cristina Sorice Baracho Thibau, João Paulo Alvarenga Brant

Publikováno v: Repositório Institucional da UFMG
Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG

A importação parcial do sistema de precedentes norte-americano pelo novo Código de Processo Civil trouxe consequências importantes no modelo de interpretação e aplicação das normas no ordenamento jurídico brasileiro. Com base em exame legal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8484522328160b4c7881598a4157aa
https://orcid.org/0000-0002-2883-2584