Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Pauline Soulas"'
Autor:
Yannick Dieudonné, Raquel Lorenzetti, Julien Rottura, Iga Janowska, Quentin Frenger, Léa Jacquel, Olivier Vollmer, Francesco Carbone, Zhu Chengsong, Marine Luka, Sabine Depauw, Nadège Wadier, Stéphane Giorgiutti, Benoît Nespola, Agathe Herb, Reinhard Edmund Voll, Aurélien Guffroy, Vincent Poindron, Mickaël Ménager, Thierry Martin, Pauline Soulas-Sprauel, Marta Rizzi, Anne-Sophie Korganow, Vincent Gies
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Primary antiphospholipid syndrome (PAPS) is a life-threatening clotting disorder mediated by pathogenic autoantibodies. Here we dissect the origin of self-reactive B cells in human PAPS using peripheral blood and bone marrow of patients with
Externí odkaz:
https://doaj.org/article/fc44155be01749a3bb66a9101bbd5846
Autor:
Nassima Bekaddour, Nikaïa Smith, Birgit Caspar, Severine Grinberg, Stephane Giorgiutti, Vincent Rodeschini, Stephanie Dupuy, Nicolas Leboulanger, Darragh Duffy, Pauline Soulas-Sprauel, Vincent Gies, Anne-Sophie Korganow, Sébastien Nisole, Jean-Philippe Herbeuval
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSystemic lupus erythematosus (SLE) is an autoimmune disease characterized by an overactive immune response, particularly involving excessive production of type I interferons. This overproduction is driven by the phosphorylation of IRF7, a
Externí odkaz:
https://doaj.org/article/a09c3482328d4c76aaf5b31c9b67450d
Autor:
Pauline Soulas-Sprauel, Bernhard Ryffel, Corentin Richard, Romain Boidot, Elise Jacquin, Raphael Carapito, Richard A Flavell, Frederique Vegran, Tiffany Martin, Isis Benoit-Lizon, Thaiz Rivera Vargas, Aurélie Roussey, Ludivine Dal Zuffo, Andréa Melis, Daria Vinokurova, Sayyed Hamed Shahoei, Alvaro Baeza Garcia, Cassandre Pignol, Stéphane Giorgiutti, Eric R Nelson, Toby Lawrence, Lionel Apetoh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/010efbccc7be494cbe7e79e2e8c14071
Autor:
Vincent Gies, Alain Wagner, Cécile Seifert, Aurélien Guffroy, Jean-D. Fauny, Anne-M. Knapp, Jean-L. Pasquali, Thierry Martin, Hélène Dumortier, Anne-S. Korganow, Pauline Soulas-Sprauel
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The pathogenesis of autoimmune diseases has not been completely elucidated yet, and only a few specific treatments have been developed so far. In autoimmune diseases mediated by pathogenic autoantibodies, such as systemic lupus erythematosus
Externí odkaz:
https://doaj.org/article/6c77ffbdd46a4c88b289d491d3de3d79
Autor:
Thierry Martin, Pierre-Edouard Gavand, Anne-Sophie Korganow, Christelle Sordet, Rose-Marie Javier, Pauline Soulas-Sprauel, Marianne Rivière, Florence Scher, Vincent Poindron, Aurélien Guffroy
Publikováno v:
Lupus Science and Medicine, Vol 6, Iss 1 (2019)
From a 1-year survival of less than 50% before the discovery of glucocorticoids to over 90% at 10 years in most dedicated centres, the spectrum of SLE has profoundly evolved. Despite this improvement, several major challenges currently remain. The ai
Externí odkaz:
https://doaj.org/article/1eecc545cac34fe386b95ef990290530
Autor:
Léa Simoni, Virginia Delgado, Julie Ruer-Laventie, Delphine Bouis, Anne Soley, Vincent Heyer, Isabelle Robert, Vincent Gies, Thierry Martin, Anne-Sophie Korganow, Bernardo Reina San Martin, Pauline Soulas-Sprauel
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Systemic lupus erythematosus (SLE) is a severe and heterogeneous autoimmune disease with a complex genetic etiology, characterized by the production of various pathogenic autoantibodies, which participate in end-organ damages. The majority of human S
Externí odkaz:
https://doaj.org/article/0e8deb68baa443e798e35ee6f9c6348a
Autor:
Jean‐Nicolas Schickel, Jean‐Louis Pasquali, Anne Soley, Anne‐Marie Knapp, Marion Decossas, Aurélie Kern, Jean‐Daniel Fauny, Luc Marcellin, Anne‐Sophie Korganow, Thierry Martin, Pauline Soulas‐Sprauel
Publikováno v:
EMBO Molecular Medicine, Vol 4, Iss 12, Pp 1261-1275 (2012)
Abstract The mechanisms behind flares of human autoimmune diseases in general, and of systemic lupus in particular, are poorly understood. The present scenario proposes that predisposing gene defects favour clinical flares under the influence of exte
Externí odkaz:
https://doaj.org/article/79f702fee8f448459736bfe5bed5e3a0
Autor:
Jean-Claude Garaud, Jean-Nicolas Schickel, Gilles Blaison, Anne-Marie Knapp, Doulaye Dembele, Julie Ruer-Laventie, Anne-Sophie Korganow, Thierry Martin, Pauline Soulas-Sprauel, Jean-Louis Pasquali
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23900 (2011)
Systemic lupus erythematosous (SLE) is an autoimmune disease with an important clinical and biological heterogeneity. B lymphocytes appear central to the development of SLE which is characterized by the production of a large variety of autoantibodies
Externí odkaz:
https://doaj.org/article/5df10ee521d74432b3708ce21b5fdc0b
Autor:
Dieudonné, Yannick, Guffroy, Aurélien, Poindron, Vincent, Sprauel, Pauline Soulas, Martin, Thierry, Korganow, Anne-Sophie, Gies, Vincent
Publikováno v:
In Autoimmunity Reviews May 2021 20(5)
Autor:
Marion Moreews, Anne-Laure Mathieu, Kevin Pouxvielh, Quentin Reuschlé, Annabelle Drouillard, Pénélope Dessay, Marie Meignien, Jiang Zhang, Lucie Fallone, Noëmi Rousseaux, Michelle Ainouze, Amaury Rey, Ommar Omarjee, Elodie Decembre, Vanina Lenief, Sophia Djebali, Olivier Thaunat, Marlène Dreux, Laurent Genestier, Thierry Defrance, Pauline Soulas-Sprauel, Antoine Marçais, Thierry Walzer, Alexandre Belot
Publikováno v:
The Journal of Immunology. 210:1209-1221
Autosomal recessive PRKCD deficiency has previously been associated with the development of systemic lupus erythematosus in human patients, but the mechanisms underlying autoimmunity remain poorly understood. We introduced the Prkcd G510S mutation th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e28e4ca99c9a490fb4e6995e6866d49e
https://doi.org/10.4049/jimmunol.2200818
https://doi.org/10.4049/jimmunol.2200818