Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pauline R. Junankar"'
Autor:
Kiaran Kirk, William A. Bubb, Pauline R. Junankar, Caroline Rae, Rongwei Teng, Pascal Mercier
Publikováno v:
NMR in Biomedicine. 22:292-302
NMR spectroscopy was used to identify and quantify compounds in extracts prepared from mature trophozoite-stage Plasmodium falciparum parasites isolated by saponin-permeabilisation of the host erythrocyte. One-dimensional (1)H NMR spectroscopy and fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1335c691c5c2efabc15c80677ea5a908
https://doi.org/10.1002/nbm.1323
https://doi.org/10.1002/nbm.1323
Publikováno v:
Cellular Physiology and Biochemistry. 14:143-154
The pathways for the efflux of K(+) from osmotically-swollen HTC rat hepatoma cells were investigated using (86)Rb(+) as a tracer for K(+). Exposure of HTC cells to a hypotonic solution ( 20 min. The second (86)Rb(+) efflux component was not inhibite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8842e590ca24e5c88955e41e2ac0b98
https://doi.org/10.1159/000078106
https://doi.org/10.1159/000078106
Autor:
Sarah H. Shafik, Kiaran Kirk, Robert L. Summers, Markus Winterberg, Adele M. Lehane, Rowena E. Martin, Rongwei Teng, Pauline R. Junankar, Donelly A. van Schalkwyk
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 34, Iss 6, p e00150 (2014)
Bioscience Reports, Vol 34, Iss 6, p e00150 (2014)
Although efforts to understand the basis for inter-strain phenotypic variation in the most virulent malaria species, Plasmodium falciparum, have benefited from advances in genomic technologies, there have to date been few metabolomic studies of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405701ba310d51e80cb9d2020e76d6c7
http://europepmc.org/articles/PMC4240024
http://europepmc.org/articles/PMC4240024
Autor:
Pauline R. Junankar, Kiaran Kirk
Publikováno v:
ResearcherID
Cells respond to osmotic swelling by releasing inorganic ions and small organic molecules (organic osmolytes). In many cell-types, osmotic swelling results in the activation of an outwardly-rectifying anion-selective current. The channel underlying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684f7f8cd71bea2d11046d3aa60d90c2
https://doi.org/10.1159/000016368
https://doi.org/10.1159/000016368
Autor:
Jorgen Mould, Suzanne M. Curtis, Gerard P. Ahern, Suzy M. Pace, Angela F. Dulhunty, Pauline R. Junankar
Publikováno v:
The Journal of Physiology. 514:313-326
1. Ryanodine receptor (RyR) Ca2+ channels in the sarcoplasmic reticulum (SR) of skeletal muscle are regulated by the 12 kDa FK506- (or rapamycin-) binding protein (FKBP12). Rapamycin can also activate RyR channels with FKBP12 removed, suggesting that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862857af0f956fa9e95061a0a1f1de5e
https://doi.org/10.1111/j.1469-7793.1999.313ae.x
https://doi.org/10.1111/j.1469-7793.1999.313ae.x
Publikováno v:
Neuroscience Letters. 225:81-84
In this report we demonstrate that the immunosuppressive drug, rapamycin, can reversibly activate the skeletal muscle ryanodine receptor calcium release channel (RyR) in terminal cisternae vesicles incorporated into planar lipid bilayers. This reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95519d703fbd9f11ce8407bf3a7fc191
https://doi.org/10.1016/s0304-3940(97)00193-6
https://doi.org/10.1016/s0304-3940(97)00193-6
Publikováno v:
Biophysical Journal. 72:146-162
FKBP12 was removed from ryanodine receptors (RyRs) by incubation of rabbit skeletal muscle terminal cisternae membranes with rapamycin. The extent of FKBP12 removal was estimated by immunostaining Western blots of terminal cisternae proteins. Single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b984c34e615ebc6f1123168f9cbf2d8c
https://doi.org/10.1016/s0006-3495(97)78654-5
https://doi.org/10.1016/s0006-3495(97)78654-5
Publikováno v:
Acta Physiologica Scandinavica. 156:375-385
This review provides a summary of current concepts about the structure and single-channel properties of ryanodine receptor calcium release channels and counter ion channels that facilitate Ca2+ release and reuptake by the sarcoplasmic reticulum. Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693bf2db2559bf4680563ab312bb3445
https://doi.org/10.1046/j.1365-201x.1996.193000.x
https://doi.org/10.1046/j.1365-201x.1996.193000.x
Publikováno v:
Biophysical Journal. 70:202-221
A comparison is made of two types of chloride-selective channel in skeletal muscle sarcoplasmic reticulum (SR) vesicles incorporated into lipid bilayers. The I/V relationships of both channels, in 250/50 mM Cl- (cis/trans), were linear between -20 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e81755f521210a5a6a15829c32cc47
https://doi.org/10.1016/s0006-3495(96)79564-4
https://doi.org/10.1016/s0006-3495(96)79564-4
Publikováno v:
Neuroscience Letters. 166:143-148
Monoclonal antibodies against ryanodine receptor (5C3) and calcium ATPase (D12) of skeletal muscle sarcoplasmic reticulum were used in an immunoelectron microscopic study of cerebellar Purkinje cells and neurons of the hypoglossal and dorsal motor nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9945bc1563dd59c5ef20ceb76e918b6b
https://doi.org/10.1016/0304-3940(94)90471-5
https://doi.org/10.1016/0304-3940(94)90471-5